132 - Predictors of Quality of Life in Adolescents with Cleft Lip and Palate

Friday, May 27, 2022

10:00 AM – 10:15 AM PT

Location: Sails Pavilion

Has Audio

Presenting Author(s)

Cathrine Fong, DDS

Resident
Children's Hospital Los Angeles
University of Southern California
Los Angeles, California, United States

Co-Author(s)

AJ

Alexis Johns, PhD, ABPP

Children’s Hospital Los Angeles, Keck School of Medicine, University of Southern California
CG

Cynthia Gong, PharmD, PhD

Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California
BG

Bocheng Gu, MS

School of Pharmacy, University of Southern California
AD

Amarjit Dass, MS

University of Southern California
SY

Stephen Yen, DMD, PhD

Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA
Los Angeles, California, United States

Research Mentor(s)

SY

Stephen Yen, DMD, PhD

Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA
Los Angeles, California, United States

Program Director(s)

AA

Alexander Alcaraz, DMD

Program Director
Herman Ostrow School of Dentistry of USC, Los Angeles, CA
Los Angeles, California, United States

Purpose: This study aimed to describe the quality of life in youth with cleft lip and palate (CLP) based on medical and sociodemographic variables.

Methods: Participants with CLP completed the Youth Quality of Life – Facial Differences, which yields 5 Perceptual subscales: Positive Consequences, Coping, Negative Consequences, Negative Self-Image, and Stigma. Multiple regression analyses were run for each subscale with predictors including sex, age, cleft type, surgery number, Great Ormond Street, London and Oslo (GOSLON) Yardstick rating, household size, socioeconomic status (SES), and insurance type.

Results: Participants (N=114) were 11-22 years old (Mean=17.8, SD=2.9) with unilateral (88%) or bilateral (22%) CLP and GOSLON ratings of 3 (14%), 4 (51%), or 5 (35%). The majority were female (57%), Latinx (68%), and had public insurance (62%). Household size was 2-15 (M=4.7, SD=1.8) and SES was mostly in the lowest category (43%). All the regression models were significant (P < .05) and explained 16-26% of subscale variance. Public insurance was a significant predictor for lower Positive Consequences (β=-0.29, P=.023) and Coping (β=-0.31, P=.018). Higher Negative Consequences was predicted by having a bilateral CLP (β=0.29, P=.009). Higher Negative Self-Image was predicted by older age (β=0.24, P=.033) and having a bilateral CLP (β=0.30, P=.005). Higher Stigma was also predicted by having a bilateral CLP (β=0.46, P < .001).

Conclusions: Quality of life in youth with CLP varied based on multiple variables that can assist providers in identifying potential risk factors for lower quality of life, which included adolescents with bilateral CLP, aged 16 years or older, and with public insurance.