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ARGs are commonly found in the gut metagenomes of pediatric HSCT recipients prior to HSCT and are associated with recent receipt of therapeutic antibiotics. Future directions for this dataset include determining the ability of ARGs in the metagenome to predict clinical outcomes, including mortality and infections. Understanding the colonization and acquisition of ARGs could inform infection prevention strategies and empiric therapies and lead to improved infectious outcomes in these high-risk patients.
Sarah M. Heston, MD
Pediatric Infectious Diseases Fellow
Duke University
Durham, NC
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Rebecca R. Young, M.S., M.S.
Biostatistician
Duke University Medical Center
Durham, North Carolina
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Mehreen Arshad, MD
Assistant Professor
Northwestern University/Lurie Children's Hospital of Chicago
Chicago, IL
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Kirsten Jenkins, BS
Clinical Research Coordinator
Duke University Medical Center
Durham, North Carolina
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Paul L. Martin, MD, PhD
Professor of Pediatrics and Division Chief of Pediatric Blood and Marrow Transplantation
Duke University Medical Center
Durham, North Carolina
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Doyle V. Ward, PhD
Associate Professor
University of Massachusetts Medical School
Worcester, Massachusetts
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Shakti Bhattarai, MS
PhD candidate
University of Massachusetts
N.Dartmouth, Massachusetts
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Vanni Bucci, PhD
Assistant Professor
University of Massachusetts
N.Dartmouth, Massachusetts
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Patrick C. Seed, MD PhD
Professor
Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Stanley Manne Children's Research Institute
Chicago, Illinois
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Matthew S. Kelly, MD, MPH
Assistant Professor of Pediatrics
Duke University Medical Center
Durham, North Carolina
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.