Professor
Feinberg School of Medicine, Northwestern University
David J. Klumpp, PhD, Professor of Urology and Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL USA.
Dr. Klumpp graduated from the University of Iowa with a BA in Biochemistry where he gained his first exposure to bench science in the laboratory of Dr. Arthur Arnone. He then spent two years a a research technician at the University of Minnesota, working with Dr. David LaPorte to identify mechanisms of metabolic regulation in E. coli. He received his PhD in Biochemistry, Molecular Biology and Cell Biology at Northwestern University in Evanston, IL. Working with Dr. Lawrence Pinto, his dissertation research defined roles of K+ channels in retinal neuron function while supporting his studies with an NIMH Sensory Biology T32 award and subsequently an NIMH F31 NRSA award. Dr. Klumpp then conducted postdoctoral research under Dr. Laimonis Laimins at the Feinberg School of Medicine in Chicago, identifying mechanisms of epithelial differential and HPV pathogenesis and supporting his studies with an NIAID F32 NRSA award. Combining these experiences, Dr. Klumpp joined the Department of Urology in 1998, working closely with Dr. Anthony Schaeffer to study mechanisms of host-pathogen interactions in UTIs as well as mechanisms of pelvic pain relevant to interstitial cystitis/bladder pain syndrome. Dr. Klumpp's work has provided insights across the spectrum of UTI pathogenesis, from urothelial signalling to host modulation by bacteria and from adaptive immune responses to pain responses. He has also contributed to our understanding of mechanisms of pelvic pain driven by mast cells and modulated by gut microbioata. Most recently, his team seeks to define mechanisms of pelvic pain modulation by CNS microglia and harness intrinstic analgesic activities of select E. coli and modulatory activities of microbiota to bring lasting pain relief to suffers of chronic pelvic pain.
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Sunday, April 30, 2023
1:05 PM – 2:05 PM CST