PD17: Kidney Cancer: Basic Research & Pathophysiology II

Saturday, April 29, 2023

9:30 AM – 11:30 AM CST

Location: S404A

CE: 1

Podium Session Moderator(s)

Jodi Maranchie, MD (she/her/hers)

Associate Professor
University of Pittsburgh

Presentations:

9:30 AM – 9:40 AM CST

PD17-01: The Impact of Loss and Mutation of Mitochondrial DNA on Oncometabolite Accumulation in Patient-Derived Fumarate Hydratase-Deficient Renal Tumor Cell Lines
Podium Presenter: Bhargav Arimilli, BS – National Cancer Institute
9:40 AM – 9:50 AM CST

PD17-02: Universal Loss of Complex I in Oncocytoma Is Associated with Defective Mitophagy via Altered Glutathione Metabolism
Podium Presenter: Lin Lin, MD, PHD – UCLA
9:50 AM – 10:00 AM CST

PD17-03: Redox imbalance and MAPK activation mediates pneumoperitoneum-induced kidney injury during minimally invasive surgery
Podium Presenter: Charbel Chalouhy, MD – Montefiore-Albert Einstein College of Medicine
10:00 AM – 10:10 AM CST

PD17-04: The role of cytoreductive nephrectomy with immune checkpoint inhibitor therapies in metastatic renal cell carcinoma murine model
Podium Presenter: Jee Soo Soo Park, MD,PhD
10:10 AM – 10:20 AM CST

PD17-05: Genomic features of renal cell carcinoma developed during end-stage renal disease and dialysis
Podium Presenter: Shigekatsu Maekawa, MD (he/him/his) – Department of Urology, Iwate Medical University
10:20 AM – 10:30 AM CST

PD17-06: Wilms Tumor: Insights Into the Role of Integrins Driving Cancer Stem Cells Self-Renewal vs. Differentiation
Podium Presenter: Astgik Petrosyan, PhD
10:30 AM – 10:40 AM CST

PD17-07: Combination Therapy for TKI Resistant Kidney Cancer via Blocking ERβ/circRNA-DGKD/miR-125-5p/VE-cadherin Signal Induced Vasculogenic Mimicry
Podium Presenter: Yixi Hu (he/him/his)
10:40 AM – 10:50 AM CST

PD17-08: Epigenetic and Epitranscriptomic Reprogramming in Renal Cancer by Oncometabolite L-2HG creates Metabolic Vulnerability
Podium Presenter: Garrett Joseph Brinkley, MD,PhD – University of Alabama
10:50 AM – 11:00 AM CST

PD17-09: CD70-Positive Extracellular Vesicles for Detection of Clear-Cell Renal Cell Carcinoma
Podium Presenter: Rodrigo R. Rodrigues Pessoa, MD,PhD
11:00 AM – 11:10 AM CST

PD17-10: Discovery of a Novel Monoclonal PD-L1 Antibody H1A That Promotes T-Cell Mediated Tumor Killing Activity in Renal Cell Carcinoma
Podium Presenter: Reza Nabavizadeh, MD (he/him/his) – Duke University
11:10 AM – 11:20 AM CST

PD17-11: Molecular Profiling Reveals Immunosuppressive Tumor Immune Microenvironment in Primary versus Paired Asynchronous Metastatic Clear Cell Renal Cell Carcinoma
Podium Presenter: Brittney Cotta, MD – MD Anderson Cancer Center
11:20 AM – 11:30 AM CST

PD17-12: Spatial molecular imaging in sarcomatoid renal cell carcinoma reveals crosstalk between immune cells and tumor cells
Podium Presenter: Allison May, MD