Session: PD27: Prostate Cancer: Localized: Surgical Therapy I
PD27-10: An Intermediate-term Oncological Assessment Comparing the Retzius-Sparing Robot Assisted Radical Prostatectomy to the Standard Approach in a Randomized Control Cohort
Introduction: Retzius sparing prostatectomy is promoted with the early continence result, but criticized for higher positive surgical margin. The long-term oncological outcome is still unknown. In this study, we aimed to compare the intermediate-term oncologic outcomes of these two approaches in a patient cohort treated as part of a randomized controlled trial. Methods: A total of 120 patients were previously randomized equally to receive retzius sparing (RS-RARP) versus standard robotic assisted laparoscopic radical prostatectomy (S-RARP) between January 2015 to April 2016. Baseline, surgical, and pathological characteristics as well as oncologic outcomes were assessed. The analysis was done based on the treatment received. Results: Sixty-three patients underwent S-RARP while 57 patients underwent RS-RARP. There was no statistically significant difference in the baseline nor surgical characteristics. The median follow up was 71.24 (IQR 59.75 - 75.75). There were more pathological T3 diseases in RS-RARP. There was no significant difference in the positive margin status nor the biochemical recurrence rate among both groups. After S-RARP and RS-RARP, 6 and 10 patients had biochemical recurrence and the 5 years biochemical recurrence free survival were 91% and 85%, respectively. (p = 0.21) Conclusions: In this cohort, there was no difference in biochemical recurrence in the patients who received either technique. Further multi-institutional studies with a larger sample size and longer follow-up are required. SOURCE OF Funding: None
