Introduction: Since the Food and Drug Administration’s (FDA) approval of the da Vinci Single-Port (SP) robotic platform in 2018, a wealth of new surgical techniques have been described that capitalize on the SP platform’s proficiency in small spaces. A rarely described technique even among robotic surgeons is the anterior retroperitoneal approach. To our knowledge, this is the first description of this approach utilizing the SP platform in the literature. Our objective is to describe the technique used at our institution for the anterior retroperitoneal single port partial nephrectomy. Methods: This video abstract uses intraoperative recordings from one patient who underwent a SP partial nephrectomy at our institution. The clinical techniques are described in detail following detailed discussion with an experience robotic surgeon (SC). No pathologic or short-term outcomes were available. Results: Retroperitoneal access was successfully obtained via an anterior incision for a 3.7 cm interpolar mass. The mass was successfully treated without need for conversion to multi-port or open approaches. Total operative time was 192 minutes. Total estimated blood loss (EBL) was 20cc. The total hospital length of stay (LOS) was 8 hours. The patient was successfully discharged home with a non-narcotic pain control plan. Conclusions: The anterior retroperitoneal approach to SP robotic partial nephrectomy is safe and feasible. Theoretical advantages of this approach include increased efficiency and decreased positional injuries due to the ability to perform surgery in the supine position, less bowel manipulation, and potentially decreased opioid requirements. Further outcomes data is anticipated. SOURCE OF Funding: None