539 - Tooth Eruption of 5-year-old Female with Congenital Zika Syndrome

The last outbreak of Zika in the United States occurred in 2015-2016. Children born to those mothers with Zika are now in early childhood. There is little research on oral manifestations of Congenital Zika Syndrome (CZS). We present the case of a 5-year-old female with CZS seen for a routine exam. She exhibited microcephaly, arthrogryposis, ophthalmic issues and hypersalivation consistent with current literature on CZS. She had at least 10 erupted and two partially erupted permanent teeth at the time, an advanced number for her age. This is contradictory to the current literature, suggesting that children with CZS exhibit late tooth eruption. As children with CZS progress through early childhood, care should be taken to systematically document oral manifestations of syndrome in order to better characterize the disease process.