Vladislav Zarayskiy, PhD
Director of Automation and Screening
Monte Rosa Therapeutics, Massachusetts, United States
Molecular glues are a type of molecules that induces proximity of two proteins that normally wouldn't interact. Known glue molecules achieve this by changing the surface of their target proteins ("neosubstrates"). The best known molecular glues are binding neosubstrates to E3 ligases, thus, causing protein degradation.
Radosław P. Nowak, PhD – Dana-Farber Cancer Institute
Jesse J. Chen, PhD – RA Capital Management
Vladislav Zarayskiy, PhD – Monte Rosa Therapeutics