(CS-057) Novel Umbilical Cord Wound Barrier in Complicated Venous Ulcer
Co-Author(s):
Introduction: 82 year old female with a history of lower leg ulcers who presented with a large, full thickness ulcer to the anterior lower leg that failed to show 50% wound closure in four weeks with standard of care. The patient has venous insufficiency, type 2 diabetes, and presented with edema on both lower extremities. This patient has had a vascular consult with no options for treatment recommended other than compression. This patient used high compression during standard of care and will continue through treatment plan. The initial wound measurements were 6.4cm x 5.6cm x 0.1cm.
Methods: Umbilical cord allografts*, were applied to the full thickness venous leg ulcer as a wound covering, providing protection while retaining endogenous growth factors. After the umbilical cord allograft*, a contact layer was placed over the wound and edges of the contact layer was secured with adhesive strips and the wound was covered with a non adherent foam dressing. After the dressings were applied high compression multilayer wraps were used.
Results: The wound experienced complete closure after two applications in two weeks with umbilical cord allograft* and standard of care together.
Discussion: This case study in a challenging chronic wound in a patient with multiple comorbidities such as venous insufficiency, type 2 diabetes, congestive heart failure, and chronic kidney disease demonstrated a notable rate of wound closure after umbilical cord allograft* applications occurred in conjunction with standard of care. Weekly applications of umbilical cord allografts* may contribute to the increased rate of wound healing. We believe that the endogenous growth factors in umbilical cord allografts* may contribute to the increased rate of wound closure.