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Cincinnati Children’s, a nonprofit academic medical center established in 1883, is one of the oldest and most distinguished pediatric hospitals in the United States. In the 2022-23 U.S. News & World Report survey of best children’s hospitals, Cincinnati Children’s ranks No. 3 among all Honor Roll hospitals. With more than 622 registered beds, Cincinnati Children’s had nearly 1.5 million patient encounters and served patients from all 50 states and 51 countries, including 589 international patients, in fiscal 2021. Cincinnati Children's Heart Institute was formed in 2008 with the mission to transform pediatric heart disease through the integration of clinical care, molecular cardiovascular research, and education. In 2022-23, U.S. News & World Report ranked Cincinnati Children’s Heart Institute one of the top programs in the nation for pediatric cardiology. The Heart Institute team has pioneered many advances in pediatric cardiology, including a first-in-nation ventricular assist device in a Duchenne Muscular Dystrophy patient, numerous transcatheter (nonsurgical) intervention therapies, echocardiography of complex cardiac malformations and the evaluation of cardiac disease during exercise stress. As one of the largest pediatric cardiology programs in the nation, the world-renowned team at the Heart Institute at Cincinnati Children’s Hospital Medical Center has achieved outcomes that rival or surpass those at other top centers, for even the most challenging cases. These outcomes are driven by a bench-to- bedside approach, which allows the Heart Institute to bring research results into mainstream treatment plans for patients before they are available elsewhere.