With the emergence of furrow-irrigated rice, ‘row-rice’, throughout the Midsouth, efforts to improve insect pest management have focused on the role of irrigation methodology and insecticide seed treatments (ISTs). In traditional flood irrigation, ISTs primarily provide protection against the rice water weevil (RWW) (Lissorhoptrus oryzophilus Kuschel), the most damaging insect pest of immature rice. However, this insect’s lifecycle is negatively impacted when removing a flood under furrow irrigation. This raises the question of whether ISTs are justified when the primary target pest is no longer a threat. Alternatively, changing irrigation methods may alter the overall pest complex and give rise to other pests not previously considered important, such as the rice billbug (Sphenophorus pertinax). Therefore, a field trial was conducted in Crowley, Louisiana to characterize the role of ISTs in row-rice using two furrow-irrigation methods (tail-water release, end-blocking) and several ISTs, alone and in combination compared to an untreated control. Larval densities of RWW and billbug were quantified per soil core and m2, respectively. Number of whiteheads due to billbug or stem borer (Family: Crambidae) injury were quantified per m2. Rice was harvested to determine whether ISTs improve yields in row-rice. Results indicate ISTs had little impact on pests nor did they protect rice yields under either irrigation method. Alternatively, differences in whiteheads and yield between irrigation methods were significant. Early signs point to irrigation strategy receiving greater emphasis in row-rice pest management than ISTs and additional growing seasons are needed to solidify this hypothesis.