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Please note that while there are no virtual sessions at EB 2022, registrants may log in to access virtual posters March 25 to May 5, 2022.
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Poster Schedule
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Tuesday, April 5, 2022
9:00 AM – 4:00 PM
Aging and Neurodegeneration
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9:00 AM – 4:00 PM
Alcohol
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9:00 AM – 4:00 PM
Anatomy
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9:00 AM – 4:00 PM
Anatomy: Animal Models
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9:00 AM – 4:00 PM
Anatomy: Gastrointestinal
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9:00 AM – 4:00 PM
Anatomy: Musculoskeletal
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9:00 AM – 4:00 PM
Anatomy: Neural
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9:00 AM – 4:00 PM
Anatomy: Respiratory
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9:00 AM – 4:00 PM
Anatomy: Urogenital
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9:00 AM – 4:00 PM
Antibacterial targets and drug discovery II
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9:00 AM – 4:00 PM
Antibiotic resistance II
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9:00 AM – 4:00 PM
Apoptosis and cell death
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9:00 AM – 4:00 PM
APS Acute Kidney Injury Poster Session
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9:00 AM – 4:00 PM
APS Acute Responses to Exercise in Health and Disease Poster Session
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9:00 AM – 4:00 PM
APS Apoptosis, Cell Stress, and Cell Death Poster Session
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9:00 AM – 4:00 PM
APS Autonomic Adjustments to Behavioral Stress Poster Session
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9:00 AM – 4:00 PM
APS Autonomic Adjustments to Exercise Poster Session
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9:00 AM – 4:00 PM
APS Autonomic Control of Cerebral and Coronary Blood Flow Poster Session
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9:00 AM – 4:00 PM
APS Barrier Function and Repair Poster Session
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9:00 AM – 4:00 PM
APS Blood Pressure and Fluid Volume Regulation in Pregnancy Poster Session
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9:00 AM – 4:00 PM
APS Cancer: Proliferation, Metastasis, and Aberrant Cell Signaling Poster Session
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9:00 AM – 4:00 PM
APS Cardiometabolic Aging Poster Session
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9:00 AM – 4:00 PM
APS Cardiovascular Regulation in Women Across the Life Span Poster Session
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9:00 AM – 4:00 PM
APS Cell Migration and Adhesion Poster Session
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9:00 AM – 4:00 PM
APS Central Regulation of Autonomic Control: Hypothalamus Poster Session
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9:00 AM – 4:00 PM
APS CEPS Trainee Poster Session
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9:00 AM – 4:00 PM
APS Comparative and Evolutionary Physiology Poster Session
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9:00 AM – 4:00 PM
APS Comparative Digestive Physiology Poster Session
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9:00 AM – 4:00 PM
APS Comparative Metabolic Physiology, Biochemistry and Endocrinology Poster Session
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9:00 AM – 4:00 PM
APS Comparative Muscle Physiology, Locomotion and Behavior Poster Session
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9:00 AM – 4:00 PM
APS Comparative Neurobiology Poster Session
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9:00 AM – 4:00 PM
APS Comparative Osmotic, Ionic, and Acid-base Regulation Poster Session
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9:00 AM – 4:00 PM
APS Comparative, Cardiovascular and Respiratory Physiology Poster Session
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9:00 AM – 4:00 PM
APS Control of Breathing: Neurotransmission and Modulation: Neural, Glial and Inflammatory Mechanisms Poster Session
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9:00 AM – 4:00 PM
APS Disease Related Physiology: Translational Medicine Poster Session
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9:00 AM – 4:00 PM
APS Exercise and Cancer Care: From the Bench to the Clinic Poster Session
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9:00 AM – 4:00 PM
APS Exercise Metabolism Poster Session
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9:00 AM – 4:00 PM
APS Gastric and Pancreatic Physiology and Pathophysiology Poster Session
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9:00 AM – 4:00 PM
APS Gastrointestinal and Liver Physiology and Pathophysiology Poster Session
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9:00 AM – 4:00 PM
APS GI and Liver Epithelial Junctions Poster Session
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9:00 AM – 4:00 PM
APS Growth Factors, Proliferation, Differentiation and Apoptosis Poster Session
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9:00 AM – 4:00 PM
APS Gut Microbiota and Inflammation
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9:00 AM – 4:00 PM
APS Heart Failure Poster Session
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9:00 AM – 4:00 PM
APS Hot Topics in Muscle Physiology Poster Session
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9:00 AM – 4:00 PM
APS Hypoxia: Cellular Responses Poster Session
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9:00 AM – 4:00 PM
APS Immunology and Microbiology of the Gut Poster Session
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9:00 AM – 4:00 PM
APS Microbiome of the GI tract Poster Session
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9:00 AM – 4:00 PM
APS Mitochondrial Metabolism and Redox Changes Poster Session
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9:00 AM – 4:00 PM
APS Muscle Wasting, Muscle Energy Balance and Aging Poster Session
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9:00 AM – 4:00 PM
APS Nuclear Receptors in the Liver and GI Tract Poster Session
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9:00 AM – 4:00 PM
APS Prebiotics, Probiotics and Gut Function Poster Session
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9:00 AM – 4:00 PM
APS Renal translational physiology Poster Session
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9:00 AM – 4:00 PM
APS Renal Water Transport, Urea Transport, and Countercurrent Mechanisms Poster Session
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9:00 AM – 4:00 PM
APS Reproductive and Fetal Endocrinology Poster Session
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9:00 AM – 4:00 PM
APS Respiratory Dysfunction in Neurological Disease and Injury: Mechanisms and Potential Therapeutics Poster Session
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9:00 AM – 4:00 PM
APS Sex Chromosomes and Sex Hormones in Cardiovascular Disease Poster Session
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9:00 AM – 4:00 PM
APS Sex Differences in Renal Function and Disease Poster Session
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9:00 AM – 4:00 PM
APS Signaling Pathways in Endocrinology and Metabolism Poster Session
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9:00 AM – 4:00 PM
APS Skeletal Muscle Microvascular Function and Metabolism: Novel Approaches, Clinical Applications, and Innovative Therapies Poster Session
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9:00 AM – 4:00 PM
APS Skeletal Muscle, Bone and Connective Tissue Poster Session
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9:00 AM – 4:00 PM
APS Skeletal Muscle; Physiology, Pathology and Metabolism in Health and Disease
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9:00 AM – 4:00 PM
APS Smooth Muscle; Physiology, Pathology and Metabolism in Health and Disease Poster Session
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9:00 AM – 4:00 PM
APS Stem Cells, Cell Growth, Development, Differentiation, and Autophagy Poster Session
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9:00 AM – 4:00 PM
APS Sympathetic Regulation in Heart Failure Poster Session
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9:00 AM – 4:00 PM
APS Sympathetic Regulation in Hypertension Poster Session
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9:00 AM – 4:00 PM
APS Transition from Acute to Chronic Critical Illness Poster Session
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9:00 AM – 4:00 PM
APS Translational Endocrinology Poster Session
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9:00 AM – 4:00 PM
APS Understanding HFpEF Pathophysiology in Animals for Novel Therapeutic Development Poster Session
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9:00 AM – 4:00 PM
APS Young Investigator Award Poster Session
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9:00 AM – 4:00 PM
ASIP Poster Viewing - Cell Death, Tissue Injury, and Repair
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9:00 AM – 4:00 PM
ASIP Poster Viewing - Digital and Computational Pathology
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9:00 AM – 4:00 PM
ASIP Poster Viewing - Gene Regulation in Development and Disease
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9:00 AM – 4:00 PM
ASIP Poster Viewing - Inflammation and Immunopathology
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9:00 AM – 4:00 PM
ASIP Poster Viewing - Pathobiology of Lung Disease
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9:00 AM – 4:00 PM
ASIP Poster Viewing -Veterinary Pathology and Animal Models of Disease
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9:00 AM – 4:00 PM
Bacteria and parasites: from microbiome to antibiotics II
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9:00 AM – 4:00 PM
Biochemical and Mechanistic Toxicology
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9:00 AM – 4:00 PM
Biogenic Amines
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9:00 AM – 4:00 PM
Cancer Cell Signaling and Drug Response
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9:00 AM – 4:00 PM
Cancer signaling and therapeutics III
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9:00 AM – 4:00 PM
Cardiac Pharmacology
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9:00 AM – 4:00 PM
Chemical biology of natural products, nucleic acids and small molecules
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9:00 AM – 4:00 PM
Chemical biology, drug discovery and bioanalytical methods III
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9:00 AM – 4:00 PM
Chemical probes, biosensors and biomarkers II
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9:00 AM – 4:00 PM
Chromatin structure, remodeling and gene expression III
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9:00 AM – 4:00 PM
CNS Transporters and Channels
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9:00 AM – 4:00 PM
Computational biology and bioinformatics II
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9:00 AM – 4:00 PM
Diabetes, obesity and metabolic syndrome III
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9:00 AM – 4:00 PM
Drug Discovery and Development - Natural Products
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9:00 AM – 4:00 PM
Drug screening and development III
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9:00 AM – 4:00 PM
Enzyme chemistry and catalysis III
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9:00 AM – 4:00 PM
Enzyme mechanisms, kinetics and energetics III
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9:00 AM – 4:00 PM
G proteins and small GTPases II
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9:00 AM – 4:00 PM
Genomics II
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9:00 AM – 4:00 PM
Genomics, glycomics, proteomics and metabolomics I
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9:00 AM – 4:00 PM
Global Health and Other Topics
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9:00 AM – 4:00 PM
Glycan binding proteins
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9:00 AM – 4:00 PM
Glycomics
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9:00 AM – 4:00 PM
Glycosyltransferases and hydrolases
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9:00 AM – 4:00 PM
Hypertension
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9:00 AM – 4:00 PM
Imaging
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9:00 AM – 4:00 PM
Inflammation and Tissue Injury
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9:00 AM – 4:00 PM
Lipids and membranes III
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9:00 AM – 4:00 PM
Membrane proteins, lipid interactions, and lipid domains III
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9:00 AM – 4:00 PM
Metabolism and cancer III
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9:00 AM – 4:00 PM
Metabolism and nutrition II
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9:00 AM – 4:00 PM
Microbe/parasite-host interactions II
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9:00 AM – 4:00 PM
Muscle
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9:00 AM – 4:00 PM
Neurobiology
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9:00 AM – 4:00 PM
Neurobiology and neuronal signaling II
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9:00 AM – 4:00 PM
Neuroinflammation
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9:00 AM – 4:00 PM
New Concepts in the Regulation of Kidney Function, Fluid Balance and Blood Pressure Poster Session
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9:00 AM – 4:00 PM
Non-coding RNAs III
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9:00 AM – 4:00 PM
Oxidative stress and reactive oxygen II
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9:00 AM – 4:00 PM
Pharmacology Education - General I
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9:00 AM – 4:00 PM
Protein interactions and binding III
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9:00 AM – 4:00 PM
Protein kinases and phosphatases II
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9:00 AM – 4:00 PM
Protein modifications I
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9:00 AM – 4:00 PM
Protein structure and biophysics III
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9:00 AM – 4:00 PM
Protein synthesis, structure, modifications and interactions III
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9:00 AM – 4:00 PM
Protein turnover, misfolding, aggregation and degradation III
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9:00 AM – 4:00 PM
Protein-small molecule interactions II
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9:00 AM – 4:00 PM
Quantitative Systems and Drug Targeting
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9:00 AM – 4:00 PM
Receptors and Signal Transduction: General
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9:00 AM – 4:00 PM
Regulation of lipid metabolism II
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9:00 AM – 4:00 PM
Renal Pharmacology
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9:00 AM – 4:00 PM
RNA processing and editing
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9:00 AM – 4:00 PM
RNA: processing, transport, and regulatory mechanisms II
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9:00 AM – 4:00 PM
Signal transduction and cellular regulation III
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9:00 AM – 4:00 PM
Transcriptional mechanisms, regulation and RNA polymerases III
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9:00 AM – 4:00 PM
Transporters in DMD
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10:00 AM – 12:00 PM
(831.1) Revisiting Pharmacology Curricula with an Anti-racist Lens
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10:00 AM – 12:00 PM
(831.2) Re-Purposing Drugs as Countermeasures for Chemical Weapon Toxicities: Interactive Pharmacology Training
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10:00 AM – 12:00 PM
(831.3) Fostering ethical reasoning in medical pharmacology through role-playing and digital tools
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10:00 AM – 12:00 PM
(831.4) The New Faculty Myth-busters: Pharmacology Educators and Curators of Information
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10:00 AM – 12:00 PM
(831.5) A Systematic Review of Assessment Practices for Self-Directed Learning in Health Professions Education
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10:00 AM – 12:00 PM
(831.6) Perception of Pharmacology Instruction and Confidence in Independent Prescription Among Osteopathic Medical Graduating Seniors
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10:00 AM – 12:00 PM
(831.7) Addressing Race, Ethnicity, and Structural Inequality in Pharmacology Education and Assessment
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10:00 AM – 12:00 PM
(832.1) Probing the Activity of Mitragyna Speciosa (Kratom) Alkaloids at Serotonin G Protein-Coupled Receptors
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10:00 AM – 12:00 PM
(832.2) Hyperactive Striatal Dopamine Signaling Observed in Huntington’s Disease Mouse Models Prior to Motor Symptom Onset Can be Attenuated via Activation of M4 Receptors
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10:00 AM – 12:00 PM
(832.3) Selective Optogenetic Dopamine Terminal Stimulation Reveals Role of GABAergic Signaling in Individual Differences in Dopamine Release
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10:00 AM – 12:00 PM
(832.4) Role of Hypothalamic Serotonin Receptors in Controlling Food Intake Following Pharmacological Administration of Leptin
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10:00 AM – 12:00 PM
(832.5) Role of Cortical Dopamine circuits in regulating Striatal Dopamine dynamics during Reversal Learning
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10:00 AM – 12:00 PM
(832.6) Targeting 5-HT1A Receptors to Correct Neuronal Hyperexcitability in Fmr1 Knockout Mice
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10:00 AM – 12:00 PM
(832.7) Carbon Fiber Multielectrode Arrays for Multiplexing Neurotransmitter Detection in Heterogeneous Brain Regions
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10:00 AM – 12:00 PM
(832.8) Novel Dopamine D4 Receptor-Selective Antagonists For Neuropsychiatric Disorders
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10:00 AM – 12:00 PM
(833.1) Sonicated hyaluronan is a potent inhibitor of Alzheimers disease progression
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10:00 AM – 12:00 PM
(833.2) Pharmacological actions of a novel and highly selective D3 dopamine receptor agonist, ML417, in a rodent model of Parkinson’s disease
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10:00 AM – 12:00 PM
(833.3) SRI 22136, A Novel Delta Opioid Receptor (DOR) Antagonist for the Treatment of Alzheimer’s Disease
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10:00 AM – 12:00 PM
(833.4) PDE4D inhibitor: a novel weapon against mild cognitive impairment and Alzheimer’s disease?
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10:00 AM – 12:00 PM
(833.5) A Connection Between DNA Repair Protein APE1, Alpha-Synucleinopathy, and Biological Sex in Rodents and Humans
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10:00 AM – 12:00 PM
(833.6) Microtubule Stabilizers as Modifiers of Alpha-Synucleinopathy
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10:00 AM – 12:00 PM
(833.7) LRRK-2 Inhibition By PF06447475 Treatment Reduces Neuronal Damage and Immune Response After Spinal Cord Trauma
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10:00 AM – 12:00 PM
(833.8) SUN11602, a novel bFGF mimetic, exerts neuroprotective effects in Parkinsons disease
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10:00 AM – 12:00 PM
(833.9) Establishing an RNA interference (RNAi) screen for neuroprotection of dopaminergic neurons in Caenorhabditis elegans models of Parkinson’s disease
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10:00 AM – 12:00 PM
(834.1) Single Molecule Analysis Reveals Dimer Formation of the Norepinephrine Transporter at the Plasma Membrane of Live Cells
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10:00 AM – 12:00 PM
(834.2) Glutamate transporter activator LDN-212320 attenuates CFA-induced cognitive deficits and anxiety-like behavior in mice
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10:00 AM – 12:00 PM
(834.3) NMDA Receptor Neuropharmacology: NMDA Receptor-mediated Calcium Transients are Attenuated by Agmatine in Mouse Spinal Cord Dorsal Horn
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10:00 AM – 12:00 PM
(834.4) Modulation of glutamate transporters as a potential therapeutic intervention for neurological disorders
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10:00 AM – 12:00 PM
(834.5) The Regulation of Glial Glutamate Transporters after in-vitro Ischemic Stroke
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10:00 AM – 12:00 PM
(834.6) Fear Processing in Mice with PMAT Deficiency
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10:00 AM – 12:00 PM
(834.7) 3,4-methylenedioxymethamphetamine (MDMA) stimulates activation of TAAR1 and subsequent neurotransmitter transporter internalization in serotonin neurons
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10:00 AM – 12:00 PM
(834.8) MKP3 Overexpression and ERK1/2 Phosphorylation in Dopaminergic Neurons Regulate DAT Trafficking and Function
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10:00 AM – 12:00 PM
(834.9) Atorvastatin Modulates the Function and Trafficking of Dopamine Transporters
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10:00 AM – 12:00 PM
(835.1) Effects of berberine on neurological recovery after spinal cord injury in rats
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10:00 AM – 12:00 PM
(835.2) The Role of Selective Adenosine Receptor Ligands on Inflammatory Pain
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10:00 AM – 12:00 PM
(835.3) The use of choline supplementation for the prevention of chemotherapy-related cognitive impairments
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10:00 AM – 12:00 PM
(835.4) Assessing the Antinociceptive Effects and Tolerance Development of Decursinol in Nociceptive, Inflammatory, and Neuropathic Pain
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10:00 AM – 12:00 PM
(835.5) Prenatal E-Cigarette Use Disrupts Blood-Brain Barrier (BBB) Integrity and Induces Pro-Inflammatory Cytokines in Postnatal Brain
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10:00 AM – 12:00 PM
(835.6) The Effects of ß-caryophyllene on Pain-Evoked and Pain-Depressed Behaviors in Rats with Chronic Inflammatory Pain
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10:00 AM – 12:00 PM
(835.7) Defining Dopamine-Mediated Changes in NLRP1, NLRC5, NLRC4, and AIM2 Inflammasomes in Human Myeloid Cells
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10:00 AM – 12:00 PM
(835.8) Renin inhibitor attenuates lipopolysaccharide-induced anhedonia and upregulation of neuroinflammatory markers in mice
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10:00 AM – 12:00 PM
(835.9) A new therapeutic target for chronic pain: GPR171 agonism reduces chronic neuropathic and inflammatory pain
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10:00 AM – 12:00 PM
(836.1) Effects of long-term ethanol consumption on cognitive function in group-housed monkeys
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10:00 AM – 12:00 PM
(836.2) Mirtazapine seeking and withdrawal in free-choice drinking model
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10:00 AM – 12:00 PM
(836.3) Hippocampal Physiological and Behavioral Deficits Related to Alcohol-induced Disruption of Local Blood Perfusion
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10:00 AM – 12:00 PM
(836.4) Brain Serotonin Deficiency Increases Susceptibility to Stress-Induced Increases in Binge Drinking in Females, but not Males
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10:00 AM – 12:00 PM
(836.5) A history of low dose ethanol modulates ventral hippocampus activity during motivated behavior
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10:00 AM – 12:00 PM
(836.6) Distinct Mechanisms of Morphine Tolerance in Enteric Neurons and Dorsal Root Ganglia Neurons: Role of β-arrestin-2
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10:00 AM – 12:00 PM
(836.7) Development of a Nonhuman Primate Model of Resistance to Punishment of Ethanol Choice
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10:00 AM – 12:00 PM
(836.8) The Effect of Spared Nerve Injury on Ethanol Reward Seeking and Reinstatement
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10:00 AM – 12:00 PM
(836.9) Mice Exposed to Chronic low-dose Ethanol Exhibit Reduced Sensitivity to Changes in Magnitude of Reward
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10:00 AM – 12:00 PM
(837.1) Development of highly potent and selective GRK5 inhibitors
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10:00 AM – 12:00 PM
(837.2) Palmitoylation of RGS20 Affects its Cellular Function
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10:00 AM – 12:00 PM
(837.3) Understanding the Molecular Mechanism of PLCε Regulation and G Protein-Mediated Activation
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10:00 AM – 12:00 PM
(837.4) Epac1 Regulates Cellular SUMOylation by Promoting The Formation of SUMO-activating Nuclear Condensates
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10:00 AM – 12:00 PM
(837.5) Differential Roles of the α and β Catalytic Subunits of PKA in the Regulation of Formoterol-modulated Gene Expression Changes in Human Airway Epithelial Cells
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10:00 AM – 12:00 PM
(837.6) Identification of Deubiquitinases (DUBs) that modulate PAR1-mediated p38 MAPK inflammatory signaling in endothelial cells
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10:00 AM – 12:00 PM
(837.7) GPCR signaling measurement and drug profiling with an automated live-cell microscopy system
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10:00 AM – 12:00 PM
(837.8) In Vitro Pharmacological Characterization of CRN04894: The First Reported Oral, Selective Nonpeptide Melanocortin 2 Receptor Antagonist Evaluated in Phase 1 First-in-Human Clinical Trials
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10:00 AM – 12:00 PM
(837.9) Identification of the Activity-Dependent Neuroprotective Protein (ADNP) as a Novel Effector of Gαi1
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10:00 AM – 12:00 PM
(838.1) Marsupsin Isolated from Polyherbal Product ABPA Rejuvenates Insulin Resistance in L6 Skeletal Muscle Cell Line via IRS1-PI3K-AKT-GLUT4 Signaling Pathway
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10:00 AM – 12:00 PM
(838.2) Isolation and Characterization of Antimicrobials from Icelandic Aquatic Bacteria
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10:00 AM – 12:00 PM
(838.3) Mitragynine Reverses Paclitaxel Chemotherapy-Induced Peripheral Neuropathy and is Mediated via Opioid Receptor Involvement
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10:00 AM – 12:00 PM
(838.4) A Peep into The Insulin Signaling Pathway of Palmatine: In Vitro, In Vivo & Ex-Vivo
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10:00 AM – 12:00 PM
(838.5) Effects of Fungus-Derived Compound N9 on Airway Mucus Secretion: In Vitro and In Vivo Studies
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10:00 AM – 12:00 PM
(838.6) Anti-inflammatory activity of xylopic acid may be attributed to the modulation of Nrf2 and NF-kB activities
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10:00 AM – 12:00 PM
(838.7) Receptor binding profiles and behavioral effects of psilocybin analogs
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10:00 AM – 12:00 PM
(838.8) Cystine-stapled Helical Peptide from Withania somnifera Is Highly Stable and Cell-permeable
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10:00 AM – 12:00 PM
(838.9) Monensin and its analogues show anti-glioblastoma activity in an organoid model of cancer
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10:00 AM – 12:00 PM
(839.1) Estrogen Sulfotransferase is Required for the Female Mice Sensitivity to T Cell-Mediated Hepatitis in an Estrogen-Independent Manner
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10:00 AM – 12:00 PM
(839.2) Brazilian Green Propolis-Based Nanostructured System: Development, Characterization and its Role in the Modulation of Cytokines in In Vitro and In Vivo Experimental Models
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10:00 AM – 12:00 PM
(839.3) miR-106b-25 Dysregulation in Complex Regional Pain Syndrome Contributes to T Cell Dysfunction
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10:00 AM – 12:00 PM
(839.4) Induction of ALOX5 during Polarization of M1 Macrophages by Multi-walled Carbon Nanotubes
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10:00 AM – 12:00 PM
(839.5) Linoleic Acid-Derived Diol 12,13-DiHOME Modulates THP-1 Macrophage NLRP3 Inflammasome Activation
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10:00 AM – 12:00 PM
(839.6) Ablation of PDE4A Exacerbates Pseudomonas aeruginosa-Induced Acute Lung Injury in Mice
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10:00 AM – 12:00 PM
(839.7) Immune Cell Regulation by Macrophage Derived Small Extracellular Vesicles in Pain
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10:00 AM – 12:00 PM
(839.8) Dietary Zinc Deficiency Increases Bisphenol A Toxicity in Diabetic Rat: Studies on the Testicular and Epididymal Pathophysiology
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10:00 AM – 12:00 PM
(839.9) Enhanced Vascular Endothelial NLRP3 Inflammasome Activation by Plasma Exosomes from Liver-specific Acid Ceramidase Gene Knockout Mice on the High Fat Diet
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10:00 AM – 12:00 PM
(840.1) Micromolar Concentrations of Methionine Aminopeptidase Inhibitor has Little Cytotoxic Effect on Cancerous and Non-Cancerous Mammalian Cells
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10:00 AM – 12:00 PM
(840.2) Effect of cadmium on aminotransferases serum activity in European carp
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10:00 AM – 12:00 PM
(840.3) NBMI Exerts Protection Against Copper Overload in HepG2 and SH-SY5Y Cell Lines
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10:00 AM – 12:00 PM
(840.4) Metabolic Effects of Sodium Fluorocitrate and Potential Treatments on Saccharomyces Cerevisiae: Changes in Oxygen Consumption
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10:00 AM – 12:00 PM
(840.5) Effect of di-ethylhexyl phthalate (DEHP) on androgen related proteins in JEG-3 placental cells
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10:00 AM – 12:00 PM
(840.6) Assessing Contractility of 3D iPSC-derived Muscle Models for Safety and Discovery Using a Novel, High-throughput, and Label-free Instrumentation Platform
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10:00 AM – 12:00 PM
(840.7) In Vitro Evaluation Of The Antimicrobial Activity Of Monolaurin Against Borrelia burgdorferi, The Lyme Disease Spirochete
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10:00 AM – 12:00 PM
(840.8) Effect of acetaminophen treatment on endocrine pathways in placenta: Proteomics investigation in JEG-3 cell model
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10:00 AM – 12:00 PM
(841.1) P-gp and Bcrp Exert Differential Impacts on Maternal and Fetal Exposure to Tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice
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10:00 AM – 12:00 PM
(841.2) Is P-glycoprotein functionally active at the Blood-CSF Barrier?
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10:00 AM – 12:00 PM
(841.3) Infection During Pregnancy Downregulates the Expression of Amino Acid Transporters in Rat and Human Placentas
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10:00 AM – 12:00 PM
(841.4) Phenobarbital induces SLC13A5 expression through activation of PXR but not CAR in human primary hepatocytes
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10:00 AM – 12:00 PM
(841.5) Ethanol Inhibits Dopamine Uptake and Augments Rewarding Effects of Cocaine via Organic Cation Transporter 3
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10:00 AM – 12:00 PM
(841.6) An Evolutionarily Conserved Residue in ABCG2 Regulates the Transport Cycle and Inhibitor Activity
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10:00 AM – 12:00 PM
(841.7) Quantitative Expression of Drug, Phospholipid and Nucleoside Transporters in the Lung Tissues across Species
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10:00 AM – 12:00 PM
(841.8) Dynamic Changes in ABCC4 Protein-Protein Interactions during PKA Signaling: Role of the ABCC4 PDZ Motif
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10:00 AM – 12:00 PM
(841.9) Importance of Probe Substrate Selection in Assessing Interactions of Tyrosine Kinase Inhibitors with Polyspecific Organic Cation Transporters
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10:00 AM – 12:00 PM
(842.1) Triple Negative Breast Cancer (TNBC) Cells Growth is Inhibited by High Dose Ascorbic Acid
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10:00 AM – 12:00 PM
(842.2) HUNK Phosphorylates Rubicon to Support Autophagy, Promoting Tumorigenesis in HER2+ Breast Cancer
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10:00 AM – 12:00 PM
(842.3) Regulation of GPCR-induced Hippo pathway signaling by ARRDC3 in breast carcinoma
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10:00 AM – 12:00 PM
(842.4) Roles for CCN proteins in Lysophosphatidic Acid and Sphingosine 1-Phosphate Signaling in Prostate Cancer Cells
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10:00 AM – 12:00 PM
(842.5) Characterizing the Contribution of Adrenergic Signaling to Olaparib Resistance in Ovarian Cancer Cells
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10:00 AM – 12:00 PM
(842.6) Synergistic Effects of Adavosertib, WEE-1 Inhibitor in Combination with Cytarabine in the Jurkat Leukemia Cell Model
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10:00 AM – 12:00 PM
(842.7) Deactivation of STAT3 and ERK and Activation of p38 in Ovarian Cancer Cells Treated with a Small Molecule Inhibitor of PTP4A3 Phosphatase
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10:00 AM – 12:00 PM
(842.8) HUNK Regulation of Interleukin 4 in Triple Negative Breast Cancer
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10:00 AM – 12:00 PM
(842.9) Amphotericin A21 Induces Cytotoxic Effects in Breast Cancer Cell Lines
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10:00 AM – 12:00 PM
(843.1) NOS isoforms facilitate Ca2+ -cycling-dependent and -independent cardiac contractility
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10:00 AM – 12:00 PM
(843.2) Sustained Exposure to the SGLT2 Inhibitor Ertugliflozin, But Not NHE-1 Inhibition By Cariporide, Attenuates Adrenergic Stimulation of Cytosolic CA2+ Levels in Spontaneously Contracting Cardiac Myocytes
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10:00 AM – 12:00 PM
(843.3) Imaging Anaplerosis in the Failing Heart by PET
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10:00 AM – 12:00 PM
(843.4) Soluble Epoxide Hydrolase Inhibitor Prevents Homocysteine-induced Cardiac Hypertrophy via Epoxyeicosatrienoic Acid–mediated Inhibition of TRPC3 Channels
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10:00 AM – 12:00 PM
(843.5) The potential role of LCZ696 in ameliorating diabetic cardiomyopathy by inhibiting the myocardial inflammation, ER stress, and apoptosis through the RAGE/NF-κB and PERK/CHOP signaling Pathways
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10:00 AM – 12:00 PM
(843.6) Cardiomyocyte-specific Adhesion G Protein-Coupled Receptor F5 mediates cardiac homeostasis and contractility
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10:00 AM – 12:00 PM
(843.7) Pentadecapeptide BPC 157 Counteracts Hemodynamic and ECG Disturbances Induced by Sotalol in Rats
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10:00 AM – 12:00 PM
(843.8) A humanized anti-cocaine mAb blocks the cardiovascular effects of cocaine in rats
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10:00 AM – 12:00 PM
(844.1) Hypertensive Dahl Salt-Sensitive Rats Demonstrate a Reduction in Central Blood Pressure Following the Short-Term Treatment with Ivabradine and Spironolactone
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10:00 AM – 12:00 PM
(844.2) Medullary overexpression of sphingosine-1-phosphate receptor 1 transgene attenuates sodium retention and hypertension in deoxycorticosterone acetate (DOCA) salt-treated mice.
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10:00 AM – 12:00 PM
(844.3) Gut commensal Coprococcus comes diminishes the blood pressure-lowering effect of ester angiotensin-converting enzyme inhibitors
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10:00 AM – 12:00 PM
(844.4) Antihypertensive Action of Exosomes Released from the Renal Medulla after Unclipping of the Renal Artery of 2 Kidney-1 Clip Hypertension Mice
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10:00 AM – 12:00 PM
(844.5) Difelikefalin, a peripherally restricted kappa opioid receptor agonist, evokes diuresis through a central kappa opioid receptor pathway
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10:00 AM – 12:00 PM
(844.6) Modulatory effect of Luteolin on potassium dichromate-induced nephrotoxicity, cardiotoxicity and genotoxicity via Kim-1/Nrf2 signaling pathways
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10:00 AM – 12:00 PM
(844.7) Downregulation of Angiotensin Type 1 Receptor by Ferulic Acid in Rat Liver Epithelial Cells
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10:00 AM – 12:00 PM
(844.8) Deletion of RGS2 Results in Increased Blood Pressure and Depression-Like Behavior in the Presence of Elevated Ang II Levels in Female Mice
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10:00 AM – 12:00 PM
(844.9) Acute Cannabigerol Administration Lowers Blood Pressure in Mice
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10:00 AM – 12:00 PM
(845.1) Protective effects of Empagliflozin against Transforming growth factor-beta-induced fibrosis in renal proximal tubular cells
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10:00 AM – 12:00 PM
(845.2) Angiotensin (1-7) exerts antioxidant effects, inhibits mTOR signaling and protects against endoplasmic reticulum stress and apoptosis in HK2 cells
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10:00 AM – 12:00 PM
(845.3) Effects of Fumarate on Blood Pressure and Renal Hemodynamics in Normotensive Rats: Possible Contribution of Sodium Potassium Co-transporter (NKCC)
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10:00 AM – 12:00 PM
(845.4) TMED-A001 Attenuates Transforming Growth Factor β1-Induced Epithelial to Mesenchymal Transition in Human Renal Proximal Tubular Cells
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10:00 AM – 12:00 PM
(845.5) Ramipril mitigates Glycerol-induced Acute Kidney Injury in Rats via its Anti-oxidant, Anti-renin and Anti-apoptosis Effects
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10:00 AM – 12:00 PM
(845.6) Attenuation of Obesity-Induced Glomerular Inflammatory Response by Inhibition of Exosome Biogenesis and Release without Changes in NLRP3 Inflammasome Activation in Podocytes
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10:00 AM – 12:00 PM
(845.7) Mitochondrial Fission and Fusion Dynamics are Regulated by Multiple Pathways in Renal Proximal Tubule Cells Treated with High Glucose
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10:00 AM – 12:00 PM
(845.8) Knockout of fatty acid amide hydrolase (FAAH) gene attenuates cisplatin-induced nephrotoxicity in mice
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10:00 AM – 12:00 PM
(846.1) Mathematical definitions of “additive effect of two (or more) drugs” and their synergism and/or antagonism based on mass-action law (MAL) algorithms for pharmacodynamics (PD), biodynamics (BD) and bioinformatics (BI) simulations
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10:00 AM – 12:00 PM
(846.2) Generative Deep Learning of the Single Cell Dose Response of 2,3,7,8 Tetrachlorodibenzo-p-dioxin in Mouse Liver
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10:00 AM – 12:00 PM
(846.3) Genetic findings in early miscarriage analysis by Chromosomal Microarray and Whole Exome Sequencing
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10:00 AM – 12:00 PM
(846.4) Evaluation of Small Molecule Inhibitors of Pseudomonas Virulence factor LasB as Non-Traditional Immunotherapeutics
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10:00 AM – 12:00 PM
(846.5) Direct targeting of epigenetic regulator Menin inhibits neuroblastoma growth
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10:00 AM – 12:00 PM
(846.6) Resistance profile of bacteria to antibiotics in city laboratories
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10:00 AM – 12:00 PM
(846.7) Targeting ligand surface density controls both complement activation and targeting efficiency of immunoliposomes
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10:00 AM – 12:00 PM
(847.1) Do We Have a New Psoriasis Drug?
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10:00 AM – 12:00 PM
(847.2) Incidence and Prevalence of Alprazolam and Clonazepam Consumption at the Hospital Level in Ecuador
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10:00 AM – 12:00 PM
(847.3) Diesel exhaust particles alter cAMP dynamics in human bronchial epithelial cells
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10:00 AM – 12:00 PM
(847.4) Modulating Intramuscular Fat Infiltration by Small Molecules
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10:00 AM – 12:00 PM
(847.5) Small extracellular vesicles induced gene expression changes in microglia
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10:00 AM – 12:00 PM
(943.1) Characterization of Buprenorphine Antagonism at Human Mu Opioid Receptors
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10:00 AM – 12:00 PM
(943.2) Distinct Spatial Conformations and Trafficking Patterns of β-arrestin Isoforms in AT1R Signaling
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10:00 AM – 12:00 PM
(943.3) Gentiopicroside ameliorates acute inflammatory kidney injury in a mouse model induced by LPS through hampering NF-κB, AP-1 and IRF3 pathways
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10:00 AM – 12:00 PM
(943.4) Structure Insights into Biased Signaling of kappa Opioid Receptor
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10:00 AM – 12:00 PM
(943.5) Effects of the Rho Kinase Inhibitor Fasudil on Adrenergic Contractions of Rat Aorta and Mouse Spleen
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10:00 AM – 12:00 PM
(943.6) DNSP-11 reduces 6-OHDA-induced caspase 3/7 activation in an SH-SY5Y cell model: Potential Role of ERK signaling pathway?
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10:00 AM – 12:00 PM
(944.1) Del Nido Cardioplegia or Potassium Induces Nrf2 and Protects Cardiomyocytes Against Oxidative Stress
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10:00 AM – 12:00 PM
(944.2) Inhibition or deletion of Adenosine A2A receptor enhances acetylcholine-induced vascular response: role of angiotensin-II in A2AAR-/- vs. C57Bl/6 mice
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10:00 AM – 12:00 PM
(944.3) Ovariectomy-Induced Arterial Stiffening is Associated with Downregulation of Tissue Resident Macrophage Markers
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10:00 AM – 12:00 PM
(944.4) Connexin43 Overexpression Exacerbates Myocardial Ischemic Reperfusion Injury in Diabetes via Modulating Cardiac Autophagy
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10:00 AM – 12:00 PM
(945.1) Effects of prometryn on cardiac and liver cell lines and mouse tissues
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10:00 AM – 12:00 PM
(945.2) Cellular and Mitochondrial Damage by the Antiviral agent Tenofovir in Renal Epithelial Cells
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10:00 AM – 12:00 PM
(945.3) Role of Human Aldehyde Oxidase in the Generation of Reactive Oxygen Species during the Metabolism of Nicotine
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10:00 AM – 12:00 PM
(945.4) Role of Cytochrome P450s in 2,4,5-Trichlorophenol Nephrotoxicity in Isolated Kidney Cells from Male Fischer 344 Rats
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10:00 AM – 12:00 PM
(946.1) Retrospective Analysis of Use of Angiotensin Receptor Blockers and Patellar Cartilage Volume Among Patients with Knee Osteoarthritis
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10:00 AM – 12:00 PM
(946.2) Antimicrobial and cytotoxicity effect of gum Arabic-silver nanoparticles
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10:00 AM – 12:00 PM
(946.3) Citronellol exerts lung protective and anti-inflammatory effects through hampering NF-κB in lipopolysaccharide-induced acute lung injury in mice
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10:00 AM – 12:00 PM
(833.10) Regional binding of [3H]-MK801 to NMDA receptors in young and aged rat brain membranes
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10:00 AM – 12:00 PM
(833.11) Novel mitoNEET ligand NL-1 improves therapeutic outcomes in an aged rat model of cerebral ischemia/reperfusion injury
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10:00 AM – 12:00 PM
(833.12) Optimizing 6-Hydroxydopamine Concentrations for induction of a Parkinson’s Disease Like Behavior in Zebrafish
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10:00 AM – 12:00 PM
(835.10) Closed Head Traumatic Brain Injury Drives Protracted Inflammation and Remodeling of Serotonergic Architecture in the Dorsal Raphe Nucleus
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10:00 AM – 12:00 PM
(835.11) Effect of BAY-117082, a NLRP3 inflammasome inhibitor, in a mouse model of nitroglycerin (NTG)-induced migraine
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10:00 AM – 12:00 PM
(835.12) Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV
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10:00 AM – 12:00 PM
(835.13) Dopamine May Exacerbate Neuroinflammation in the Context of HIV by Driving Inflammatory Phenotypes in Macrophages
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10:00 AM – 12:00 PM
(835.14) The selective inhibitors for heat shock protein 90 beta reduce the lipopolysaccharide (LPS)-induced inflammatory response via inhibiting the activation of NF-κB and ERK MAPK in BV2 microglial cells
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10:00 AM – 12:00 PM
(837.10) Development of Transgenic Mouse Models for the Expression of Optical Biosensors of Endogenous G Protein Activity
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10:00 AM – 12:00 PM
(837.11) Persistent Inflammation Induces Desensitization of the Presynaptic Cannabinoid 1 Receptor in the Ventrolateral Periaqueductal Gray
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10:00 AM – 12:00 PM
(837.12) Identifying Novel Signaling Mechanisms Downstream of Gq-Coupled Receptors
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10:00 AM – 12:00 PM
(837.13) G protein-coupled receptor kinases regulate β-arrestin interactions with the D2 dopamine receptor in an isoform-specific manner and in the absence of direct receptor phosphorylation
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10:00 AM – 12:00 PM
(837.14) High-throughput CRISPR for Generating Therapeutic Nanobodies
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10:00 AM – 12:00 PM
(837.15) Structure-Function Relationship of the 20-HETE-GPR75 pairing: Development and characterization of agonist, partial agonists, and receptor blockers
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10:00 AM – 12:00 PM
(837.16) A Novel Curcumin Isomer, cis-trans Curcumin, Activates Adenosine Receptor Subtypes A1 And A3: Potential for Pain Therapy
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10:00 AM – 12:00 PM
(837.17) G protein-coupled receptor regulation of the alpha-arrestin ARRDC3
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10:00 AM – 12:00 PM
(837.18) Screening of Non-Purine Ligands Binding to Adenosine Receptors A1, A2A, A2B, and A3
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10:00 AM – 12:00 PM
(837.19) Gs-coupled GPCR-mediated Activation of Rapgef2- and ERK-dependent Gene Regulation and Neuritogenesis in NS-1 Cells
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10:00 AM – 12:00 PM
(837.20) Dynamic Desensitization of Gaq Signaling and Gaq-dependent GPCR Crosstalk by GRKs
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10:00 AM – 12:00 PM
(837.21) Distinct Signaling of Native PTH-related Peptide
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10:00 AM – 12:00 PM
(837.22) Determining the Requirements for Gαi:β-arrestin Complex Formation at G Protein-Coupled Receptors
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10:00 AM – 12:00 PM
(837.23) The Role of SDF-1 in Signaling Differences Between CXCR4 and Atypical ACKR3 Chemokine Receptors
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10:00 AM – 12:00 PM
(837.24) Modulation of GPCR Rhodopsin Function by Membrane Lipids and Water
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10:00 AM – 12:00 PM
(837.25) Regulation of Endothelial Cell function by Integration of Gαi and β-arrestin signaling at Atypical Chemokine Receptor 3
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10:00 AM – 12:00 PM
(838.10) Elucidating Pharmacological Activities of Volatile Chemotypes in Essential Oil of Morina longifolia
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10:00 AM – 12:00 PM
(839.10) Anti-inflammatory effects of Angiotensin-(1-7) through Renin-Angiotensin System and Arachidonic Acid Pathway
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10:00 AM – 12:00 PM
(839.11) Acat-1 Inhibition Reduces Inflammatory Response to Bleomycin-mediated Lung Injury
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10:00 AM – 12:00 PM
(839.12) Mechanisms of Nitroalkene Inhibition of TLR4 Mediated Macrophage Activation
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10:00 AM – 12:00 PM
(841.10) Impact of loss or regain of Equilibrative Nucleoside Transporter (ENT) Subtype-1 on ENT Subtype-2 pharmacology in a Novel CRISPR-Cas9 HEK293-ENT1KO Cell Model
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10:00 AM – 12:00 PM
(841.11) How does S-palmitoylation affect the Organic Anion Transporting Polypeptide 1B1 (OATP1B1)?
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10:00 AM – 12:00 PM
(841.12) Downregulation of BCRP (ABCG2) in Placenta of Rat Model of Preeclampsia
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10:00 AM – 12:00 PM
(841.13) Is Protein-Mediated Uptake Of Drugs By OATPs, Via Protein-Lipid Interaction, A Real Phenomenon Or An Artifact?
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10:00 AM – 12:00 PM
(841.14) The Function and Surface Expression of the Organic Cation Transporter 1 (OCT1) is Affected by Free Cholesterol
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10:00 AM – 12:00 PM
(841.15) Silymarin-mediated Natural Product–Drug Interactions involving Enteric Organic Anion Transporting Polypeptides
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10:00 AM – 12:00 PM
(841.16) One Assay, Two Vital Values-Estimating Intrinsic Permeability and Efflux Using MDCK-MDR1 Assay
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10:00 AM – 12:00 PM
(842.10) A β-catenin-TCF-sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer
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10:00 AM – 12:00 PM
(842.11) Functional Comparison of Human and Murine Equilibrative Nucleobase Transporter 1
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10:00 AM – 12:00 PM
(842.12) A reducible comparison of 2D vs. 3D HepG2 culture-derived sEV characteristics and cancer pathway-related miRNA content
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10:00 AM – 12:00 PM
(842.13) Lipin Expression Correlates to Differences in Phospholipid Profiles in Drug-Resistant Prostate Cancer Cells
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10:00 AM – 12:00 PM
(842.14) Characterization of An Inducible p65 Knockout Mouse Model for Studying Glioblastoma
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10:00 AM – 12:00 PM
(842.16) The role of altered calcium signaling and handling as an underlying mechanism of drug tolerance in BRAF mutant melanoma
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10:00 AM – 12:00 PM
(842.17) Sumac Induces Mitochondria-Dependent Cellular Toxicity in Human Pancreatic Cancer Cell Lines
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10:00 AM – 12:00 PM
(842.18) G9a Responds to KRAS-Mediated Replication Stress by Increased Origin Licensing
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10:00 AM – 12:00 PM
(842.19) Investigating the Anticancer Activity of Novel Norethindrone Derivatives in PC3 Prostate Cancer Cells
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10:00 AM – 12:00 PM
(842.20) Clinical involvement of Dickkopf protein-related protein 3 (DKK3) and Prolyloligopeptidase with tumor progression and metastasis onset of Glioblastoma multiforme
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10:00 AM – 12:00 PM
(842.21) Characterizing a Canine Urothelial Carcinoma Model of Acquired MEK1/2 Inhibitor Resistance
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10:00 AM – 12:00 PM
(842.22) Regulation of Glioblastoma Stem Cell Properties and Tumor Invasion by G⍺12 Signaling
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10:00 AM – 12:00 PM
(842.23) Mechanistic Elucidation of an Anti-Epileptic for the Treatment of Glioblastoma
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10:00 AM – 12:00 PM
(842.24) Specificity of Binding and Antitumor Efficacy of a Covalent Microtubule Stabilizer
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10:00 AM – 12:00 PM
(842.25) Evaluation of a Combination of an HDAC Inhibitor and a Cell Cycle Inhibitor in Pancreatic Cancer Cells
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10:00 AM – 12:00 PM
(844.10) Uncovering a sex-specific role for olfactory receptor 558 (Olfr558) in blood pressure regulation
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10:15 AM – 12:15 PM
(775.1) Anatomical Study of Abdominal Wall Muscles Innervation
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10:15 AM – 12:15 PM
(775.2) Anatomical Structures Object Library of the Human Reference Atlas
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10:15 AM – 12:15 PM
(775.3) Frequency, variation, and structure of the median artery in a cadaver sample from New Mexico
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10:15 AM – 12:15 PM
(775.4) Surgical Anatomy of the occipital condyle and its relation to hypoglossal canal
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10:15 AM – 12:15 PM
(775.5) Three-Dimensional Visualization and Measurement of the Liver and Gallbladder and Their Spatial Orientation
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10:15 AM – 12:15 PM
(775.6) Is it Possible to do Quality Science in Anatomy? Brazilian Scientists say Yes!
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10:15 AM – 12:15 PM
(775.7) A Novel En Bloc Circulatory System Dissection: A Teaching Tool for Systems-Based Medical School Curricula
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10:15 AM – 12:15 PM
(775.8) Ultrastructure of the mammary gland in lactating Saanen goats
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10:15 AM – 12:15 PM
(775.9) Supernumerary Branches of the Dorsomedial Cutaneous Nerve of the Hallux Crossing the Extensor Hallucis Longus Tendon
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10:15 AM – 12:15 PM
(776.1) Conservation of Kidney Development in the Red-eared Slider, Trachemys scripta
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10:15 AM – 12:15 PM
(776.2) Effects of Chronic Stress on Food Preference and Penile Morphology in Rats
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10:15 AM – 12:15 PM
(776.3) Development of humanized ACE2 mouse and rat models for COVID-19 research
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10:15 AM – 12:15 PM
(776.4) Histological study of a low-cost embalming technique with preservation for nearly three years at room temperature
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10:15 AM – 12:15 PM
(776.5) Pharmacological inhibition of ER stress mitigates testicular pathology in hind-limb unloaded mice
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10:15 AM – 12:15 PM
(776.6) Craniofacial morphology of a new mouse model of Down syndrome
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10:15 AM – 12:15 PM
(777.1) Spexin Co-localizes with Insulin in Pancreatic Islet Cells of Normal and Diabetic Rats
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10:15 AM – 12:15 PM
(777.2) Correlation Between Liver Weight and Dimensions to Patient Demographics
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10:15 AM – 12:15 PM
(777.3) Use of flavonoids with antioxidant potential to prevent morphophysiological intestinal damage induced by the antineoplastic fluorouracil
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10:15 AM – 12:15 PM
(777.4) Novel roles for rRNA and ribosome biogenesis associated factors in neural crest cell colonization of the gut and in the pathogenesis of Hirschsprung disease
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10:15 AM – 12:15 PM
(777.5) SPARC: The structure of vagal nociceptive nerve fibers in the mouse esophagus.
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10:15 AM – 12:15 PM
(777.6) The Flavonoid Troxerutin Prevents Tissue Damage and the Alteration of Cellularity Residing in Intestinal Mucositis by 5-Fluorouracil
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10:15 AM – 12:15 PM
(777.7) The Trunk of Henle and its Variants
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10:15 AM – 12:15 PM
(777.8) Neuroanatomical Remodeling of Colonic Interstitial Cells of Cajal after Spinal Cord Injury
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10:15 AM – 12:15 PM
(778.1) SPARC: Intersectional labeling of vagal afferent nerve subsets using Cre and FLP dependent dual reporter strain
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10:15 AM – 12:15 PM
(778.2) SPARC: Visualization of genetically-labeled vagal and spinal afferent subsets innervating the mouse lung
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10:15 AM – 12:15 PM
(778.3) Upper airways dysmorphology and obstructive sleeping apnea in Down syndrome
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10:15 AM – 12:15 PM
(778.4) MMA: The Fight Against Sleep Apnea
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10:15 AM – 12:15 PM
(779.1) Anomalous Obturator Arteries with Multiple Pelvic Branches: A Urogynecological Approach Alexandra N. Acevedo-Arroyo1, Camille L. Santiago-Negrón1, Carlos Fonseca-Salgado2, Sofía Jiménez-Dietsch1 and Jailenne I. Quiñones-Rodríguez1 1Department of Anatomy and Cell Biology, Universidad Central del Caribe School of Medicine, Bayamón, Puerto Rico 2Obstetrics and Gynecology Department, San Juan City Hospital, San Juan, Puerto Rico
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10:15 AM – 12:15 PM
(779.2) Telocytes: Newly Discovered Interstitial Cells in the Human Female Internal Reproductive Organs – Identification of a Suitable Immunohistochemical Marker and Possible Significance in the Pathogenesis of Uterine Fibroids
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10:15 AM – 12:15 PM
(779.3) Bilateral extra-renal pelvises and calyxes with additional renal blood vessel variations identified in a single prosected medical school donor body
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10:15 AM – 12:15 PM
(779.4) Effect of Social Isolation on Ovarian Follicles in Female Mice
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10:15 AM – 12:15 PM
(779.5) Immunologically active cells and infertility - Quantification of uterine Natural Killer cells in endometrial samples from patients with recurrent implantation failure
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10:15 AM – 12:15 PM
(779.6) Microscopic anatomical background of unexplained tubal infertility – three new possible causes
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10:15 AM – 12:15 PM
(780.1) A Qualitative Comparison of Manual and K-means Segmentation for Whole-slide Histology Images of Rabbit Vocal Folds
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10:15 AM – 12:15 PM
(780.2) A review of Melodic Intonation Therapy (MIT) and pilot of Dynamic Adaptive Speech Reconstruction (DASR) imaging
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10:15 AM – 12:15 PM
(780.3) Optimizing Newborn Primate Endocast Reconstruction in 3DSlicer
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10:15 AM – 12:15 PM
(780.4) Are Surface Models Obtained Using Different Methodologies Comparable?
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10:15 AM – 12:15 PM
(780.5) Digital Dissection with CT Scans Enhances Anatomy Education: First-year Medical Students’ Perception of Radiology Teaching During the Covid-19 Pandemic
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10:15 AM – 12:15 PM
(780.6) Analytical Needs for Machine Learning-based Image Analysis of Brainstem Astrocyte Cell Function
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10:15 AM – 12:15 PM
(780.7) Cadaveric Transilial Bone Biopsy: An Effective and Economic Approach to Study Bone Health
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10:15 AM – 12:15 PM
(780.8) Quantitative analysis of straight length of the external ear
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10:15 AM – 12:15 PM
(780.9) 3D-Printing Offers Dry Replication and New Insight into Unique Museum Specimens
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10:15 AM – 12:15 PM
(781.1) Psoas Minor: Major Confusion
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10:15 AM – 12:15 PM
(781.2) Palisade Endings in Extraocular Muscle Exhibit Clear Motor Features but their Exact Function is still not known
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10:15 AM – 12:15 PM
(781.3) Role of cardiomyocytes in right ventricle viscoelasticity with pulmonary hypertension development
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10:15 AM – 12:15 PM
(781.4) Distinct Effects of Mesterolone on Oxidative and Glycolytic Fibers of Avian Skeletal Muscle
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10:15 AM – 12:15 PM
(781.5) D230025D16Rik: A Novel Regulator of Muscle Cell Differentiation
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10:15 AM – 12:15 PM
(782.1) Effects of Dietary Pattern on Average Cortical Bone Density and Estimated Thickness of the Proximal Ulna
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10:15 AM – 12:15 PM
(782.2) Morphometric Aspects ot the Alba and Lunate Lineas and Correlations with the Physiological Diastasis of the Rectus Abdominis Muscles: Prospective Study
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10:15 AM – 12:15 PM
(782.3) Musculoskeletal Differences Between Amputated and Non-Amputated Lower Limbs
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10:15 AM – 12:15 PM
(782.4) A New Method for Quantifying 3D Skeletal Morphology in Living Subjects Using Low-Dose Stereo Radiographs
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10:15 AM – 12:15 PM
(782.5) Functional Modularization in the Neck Muscles of the Gerenuk (Litocranius walleri)
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10:15 AM – 12:15 PM
(782.6) Anatomical Variants of the Intercostobrachial Nerve and their Clinical Implications in Axillary Dissection
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10:15 AM – 12:15 PM
(782.7) Stretching the Face: Mimetic Muscles Have Muscle Spindles
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10:15 AM – 12:15 PM
(782.8) Teres Intermedius: An Accessory Rotator Cuff Muscle Discovered During Routine Cadaveric Dissection
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10:15 AM – 12:15 PM
(782.9) Unusual Nervous Contribution to the Formation of the Inferior Gluteal Nerve: Clinical and Surgical Outcomes
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10:15 AM – 12:15 PM
(783.1) A Fight Against Gut Dysbiosis: Dendritic-cell Derived Hepcidin and its Healing Role and Prevention of Neurologic Disease Authors: Barbara Kania, Alexis Sotelo, Darren Ty, Jonathan J. Wisco, PhD
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10:15 AM – 12:15 PM
(783.2) Gut Dysbiosis: A Review of the Effects of a High-Fat Diet on Iron Regulation and Brain-Derived Neurotrophic Factor (BDNF) Expression in the Brain-Gut Axis
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10:15 AM – 12:15 PM
(783.3) Glyphosate increases anxiety-like behavior and threat response to novel neutral stimuli
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10:15 AM – 12:15 PM
(783.4) Mixed Cerebrovascular And Alzheimer’s Type Pathology Mimicking Lewy Body Disease And Its Possible Contribution To the Increased Risk of Developing Cognitive Impairment In Elderly Patients with Bipolar Disorder/Schizophrenia
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10:15 AM – 12:15 PM
(783.5) Sleep Disruption Exacerbates Cognitive Dysfunction by Promoting Lipid-Immune Dysregulation in the Corticohippocampal System of Pentylenetetrazol-Kindled Rats
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10:15 AM – 12:15 PM
(783.6) Brain dysmorphologies associated with Alzheimer disease in Down syndrome
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10:15 AM – 12:15 PM
(783.7) Closed-head injury increased platform-mediated avoidance in rats
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10:15 AM – 12:15 PM
(783.8) Maternal sleep disordered breathing during gestation produces sexually dimorphic autism-relevant synaptic and behavioral aberrations in the offspring associated with excessive mTOR cortical signaling
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10:15 AM – 12:15 PM
(783.9) Investigating White Matter Inflammatory Cells and their Relationship with Beta-Amyloid in Alzheimers Disease
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10:15 AM – 12:15 PM
(784.1) Morphological Characteristics of Tubular Polymeric Scaffold to Improve Peripheral Nerve Regeneration
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10:15 AM – 12:15 PM
(784.2) An Exploration of the Sympathetic Component of the Recurrent Laryngeal Nerve
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10:15 AM – 12:15 PM
(784.3) The Origin of Sympathetic Postganglionic Fibers in the Cervical Region of the Vagus Nerve
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10:15 AM – 12:15 PM
(784.4) Estimates of Resolution, Sensitivity, and Parallax Are Insufficient Parameters to Model the Visual Contributions to Animal Locomotor Performance
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10:15 AM – 12:15 PM
(784.5) The Relevance of the Adamkiewicz Artery Anatomical Variations for Resection of Spinal Tumors
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10:15 AM – 12:15 PM
(784.6) An Anatomical Study of The Central Myelin Portion And Transitional Zone of The Oculomotor And Abducens Nerves
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10:15 AM – 12:15 PM
(784.7) Morphometric analysis of the tentorial notch by magnetic resonance
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10:15 AM – 12:15 PM
(849.1) What Doesnt Kill You Makes You Stronger—Even Heart Radiation?
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10:15 AM – 12:15 PM
(849.2) The Influence of Covid-19-Based mRNA Vaccines on Measures of Conduit Artery and Microvascular Endothelial Function
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10:15 AM – 12:15 PM
(849.3) Utilization of zebrafish larvae to monitor gastric motility in diabetes mellitus: targeting GLP-1 and GIP receptors
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10:15 AM – 12:15 PM
(849.4) Chronic Vagal Nerve Stimulation Rescues Sympathetic Control of the Heart following Myocardial Infarction
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10:15 AM – 12:15 PM
(849.5) Cardiac Fibroblasts Secrete Galectin-1 After Myocardial Infarction to Communicate With Macrophages
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10:15 AM – 12:15 PM
(849.6) Impairment in endothelial bioenergetics contributes to diabetes-induced vascular dysfunction
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10:15 AM – 12:15 PM
(849.7) sFlt1-Induced Preeclampsia Enhances Cardiovascular Response to Post Partum Hypertensive Stimuli via Smooth Muscle Mineralocorticoid Receptor
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10:15 AM – 12:15 PM
(849.8) Assessment of hindlimb myopathy and mitochondrial bioenergetics in a unique mouse model of access-related hand dysfunction
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10:15 AM – 12:15 PM
(849.9) Loss of Mitochondrial Dynamics Proteins Mitofusin-2 and Drp-1 in Myocardial Ischemia-Reperfusion Injury Is Prevented by Matrix Metalloproteinase-2 Preferring Inhibitors
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10:15 AM – 12:15 PM
(850.1) Effects of aging and type 2 diabetes on cardiac structure and function: Underlying mechanisms
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10:15 AM – 12:15 PM
(850.2) Overexpression of Skeletal Muscle Nrf2 Protects Against Aging-Associated Dysfunction in Skeletal Muscle and Heart
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10:15 AM – 12:15 PM
(850.3) Sex Differences and Cardiovascular Diseases in Down Syndrome
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10:15 AM – 12:15 PM
(850.4) Changes in Gut Microbiome Composition with Healthy Aging in Humans: Links to Vascular Endothelial Function
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10:15 AM – 12:15 PM
(850.5) Subcellular Recycling of CD36 as Target to Rescue Lipid Overload-induced Myocardial Contractile Dysfunction
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10:15 AM – 12:15 PM
(850.6) Individuals with Acute Spinal Cord Injury Display Impaired Biomarkers of Cardiometabolic Health
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10:15 AM – 12:15 PM
(850.7) The Effects of High Salt and Western Diets on Microcirculatory and Glycocalyx Properties in Genetically Heterogeneous Young Mice
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10:15 AM – 12:15 PM
(850.8) Microvascular Function in Skeletal Muscle of Adiponectin Knockout Mice
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10:15 AM – 12:15 PM
(850.9) Aortic Stiffness is Negatively Associated with Microvascular Glycocalyx Thickness and Microvascular Perfusion among Older Adults: Role of Carotid Pressure Pulsatility
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10:15 AM – 12:15 PM
(851.1) Changes in Cardiac and Vascular Contractile Protein in a Rat Model of Heart Failure with Preserved Ejection Fraction
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10:15 AM – 12:15 PM
(851.2) Regulation of NAD Metabolism in Diastolic Dysfunction Induced by Metabolic Stress
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10:15 AM – 12:15 PM
(851.3) Decreased Mitochondrial Unfolded Protein Response (UPRmt) in HFpEF
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10:15 AM – 12:15 PM
(851.4) Nitric Oxide Therapy Attenuates Heart Failure with Preserved Ejection Fraction
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10:15 AM – 12:15 PM
(851.5) HFpEF in CKD is Associated with Elevated TNF-α/IL-6 Inflammatory Signaling from the Kidney
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10:15 AM – 12:15 PM
(851.6) Long Non-coding RNAs Mediate Heart Failure with Preserved Ejection Fraction Associated with Thyroid Dysfunction
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10:15 AM – 12:15 PM
(851.7) Remote Hind-Limb Ischemia Mechanism of Preserved Ejection Fraction During Heart Failure
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10:15 AM – 12:15 PM
(851.8) Computational Modeling using Artificial Neural Networks Identifies Chamber-Specific Predictors of Cardiac Collagen Content in Ovariectomized and Aortic-Banded Yucatan Mini-Swine
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10:15 AM – 12:15 PM
(851.9) Chronic High-Rate Pacing Induces Heart Failure with Preserved Ejection Fraction-Like Phenotype in Obese Ossabaw Swine
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10:15 AM – 12:15 PM
(852.1) Nexinhib20 prevents myocardial ischemia-reperfusion injury by inhibiting neutrophil adhesion and β2 integrin activation
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10:15 AM – 12:15 PM
(852.2) Anti-depressant lithium compounds reliefs cardiorespiratory disturbances and improves cardiac function in experimental non-ischemic heart failure
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10:15 AM – 12:15 PM
(852.3) Scleraxis is Required for Induction of GLS1 Expression in Cardiac Myofibroblasts
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10:15 AM – 12:15 PM
(852.4) Transcriptomic Analysis of Splenic Leukocytes Reveals a Norepinephrine-Mediated Dynamic Immune Cell Deployment Mechanism in Heart Failure Rat
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10:15 AM – 12:15 PM
(852.5) Immune cells play a crucial role in the development of a cardiac dysfunction in cardiac p38 MAPKa KO mice after pressure overload
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10:15 AM – 12:15 PM
(852.6) Evaluation of Exercise-Induced Changes in Lung Water Density in Heart Failure with Preserved Ejection Fraction
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10:15 AM – 12:15 PM
(852.7) Manipulation of Left Ventricular Loading Conditions is Necessary to Identify Diastolic Dysfunction in Swine with Repetitive Pressure Overload-Induced HFpEF
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10:15 AM – 12:15 PM
(852.8) Myeloid YAP Inhibition Improves Cardiac Phenotype During Pressure Overload Stress
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10:15 AM – 12:15 PM
(852.9) The Impact of Short-Term Tetrahydrobiopterin (BH4) Supplementation on Peripheral Vascular Function in Heart Failure with Preserved Ejection Fraction (HFpEF)
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10:15 AM – 12:15 PM
(853.1) Moringa oleifera extract protects against rhabdomyolysis-induced acute kidney injury
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10:15 AM – 12:15 PM
(853.2) RIP3 translocation into Mitochondria promotes Mitofilin degradation to increase inflammation and kidney injury after renal ischemia/reperfusion
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10:15 AM – 12:15 PM
(853.3) Meprin β Modulates Cellular Proliferation Through The IL-6 Signaling Pathway In IRInduced Kidney Injury
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10:15 AM – 12:15 PM
(853.4) Meprin β mediates Osteopontin-Signaling in IR-Induced Acute Kidney Injury
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10:15 AM – 12:15 PM
(853.5) Meprin β meidates Apoptosis/Survival Through The IL-6-Mediated JAK/STAT Signaling Pathway In Ischemia/Reperfusion-Induced Kidney Injury
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10:15 AM – 12:15 PM
(853.6) Meprin β Regulates Protein Kinase A Mediated TGF-β Signaling in Ischemia Reperfusion-Induced Kidney Injury
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10:15 AM – 12:15 PM
(853.7) Renal Venous Clamping Exacerbates Outer-Medullary Red Blood Cell Congestion during Ischemia in Male and Female WKY Rats
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10:15 AM – 12:15 PM
(853.8) Delayed Reperfusion of the Renal Outer Medulla Attenuates Ischemia Reperfusion-Induced Vascular Congestion
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10:15 AM – 12:15 PM
(853.9) Does G protein-coupled Estrogen Receptor 1 Contribute to Cisplatin-induced Acute Kidney Injury?
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10:15 AM – 12:15 PM
(854.1) NaCl Intake Promotes Greater Increases in Blood Pressure Than NaHCO3 in Rats with Chronic Kidney Disease
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10:15 AM – 12:15 PM
(854.2) Optimization of Renal Delivery of an MMP2-inhibitory Peptide Delivered Using the Elastin-like Polypeptide Carrier
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10:15 AM – 12:15 PM
(854.3) Endothelin-1 via ETA receptor activation promotes renal iron deposition in murine models of iron overload
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10:15 AM – 12:15 PM
(854.4) Mechanisms in Chronic Kidney Disease and Associated Cardiovascular Remodeling Contributes to the Progression of Cognitive Impairment in Women
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10:15 AM – 12:15 PM
(854.5) Reduced Hippocampal Neuronal Activity and Impaired Cognitive Function in a Mouse Model of Chronic Kidney Disease
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10:15 AM – 12:15 PM
(854.7) Urinary Serpin-A3 is an Early Predictor of Clinical Response to Therapy in Patients with Proliferative Lupus Nephritis
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10:15 AM – 12:15 PM
(854.8) Gitelman-like syndrome caused by pathogenic variants in mitochondrial DNA
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10:15 AM – 12:15 PM
(855.1) A Mathematical Model of the Rat Kidney IV: Whole-Kidney Response to Hyperkalemia
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10:15 AM – 12:15 PM
(855.2) Lithium-associated nephrotoxicity: role of GDF15-mediated collecting duct cells proliferation
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10:15 AM – 12:15 PM
(855.3) Synergistic Contribution of Epac1-/- and Epac2-/- for Urinary Concentrating Ability
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10:15 AM – 12:15 PM
(855.4) Aldosterone Regulates Vasopressin Escape through Changes in Water and Urea Transporters
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10:15 AM – 12:15 PM
(855.5) Empagliflozin Accelerates Escape from Vasopressin in Rats
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10:15 AM – 12:15 PM
(856.1) Renal adaptations in gestational hypertension preserves K+ while minimizing Na+ retention
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10:15 AM – 12:15 PM
(856.2) Role of the JAK/STAT3 Pathway in Obesity-Induced Renal Injury in Polycystic Ovary Syndrome
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10:15 AM – 12:15 PM
(856.3) Glutathione peroxidase 4 prevents 12/15 LOX induced renal oxidative cell death and improves renal post Ischemic recovery in Male Spontaneous Hypertensive Rats (SHR)
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10:15 AM – 12:15 PM
(856.4) Obeticholic Acid Prevents Fibrosis in a Model of Tubulointerstitial Kidney Disease
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10:15 AM – 12:15 PM
(856.5) Sex Difference in Autoregulatory Responses of Juxtamedullary Afferent Arterioles Following Ischemia-Reperfusion in Rats
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10:15 AM – 12:15 PM
(856.6) Obesity Exacerbates Lipid Nephrotoxicity and Renal Injury in a Model of Ovarian Hormone Deficiency
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10:15 AM – 12:15 PM
(856.7) Sex Difference in Renal Artery Contractility in a Novel CRISPR/Cas9-Generated P2X7 Knockout Rat
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10:15 AM – 12:15 PM
(856.8) The Role of the Androgen Receptor in Sexual Dimorphisms in Acidosis-Stimulated Renal Ammonia Metabolism
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10:15 AM – 12:15 PM
(856.9) Key renal metabolic differences in healthy male and female Sprague Dawley rats
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10:15 AM – 12:15 PM
(857.1) Sexual Dimorphism in Brain Cellular Senescence During Angiotensin II-Induced Hypertension
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10:15 AM – 12:15 PM
(857.2) Impact of Maternal Obesity on Resting Muscle Sympathetic Nerve Activity during Normotensive Pregnancy
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10:15 AM – 12:15 PM
(857.3) Effect of Parity on Cardiovagal Baroreflex Sensitivity and Blood Pressure Variability in Sequential Pregnancies and Postpartum
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10:15 AM – 12:15 PM
(857.4) Impact of Gonadectomy on Sex-Selective Dysregulation of Cardiovascular Function Resulting From In Utero Exposure to Dexamethasone
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10:15 AM – 12:15 PM
(857.5) Dietary nitrate supplementation attenuates the mechanoflex in older women with early menopause: A pilot study
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10:15 AM – 12:15 PM
(857.6) Effects of Dietary Nitrate Supplements on Morning Blood Pressure Surge and Sympathetic Neural Control during Orthostasis in Post-menopausal Women
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10:15 AM – 12:15 PM
(857.7) Menopausal Hot Flashes and Renal Function
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10:15 AM – 12:15 PM
(857.8) Sleep Disturbance and Sympathetic Reactivity in Menopausal Women
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10:15 AM – 12:15 PM
(857.9) Cardiovascular Reactivity During a Fatiguing Exercise in Women: The Influence of Menopause Duration and Age
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10:15 AM – 12:15 PM
(858.1) Cardiopulmonary protection against nicotine-induced pulmonary hypertension and right ventricular remodeling in mice is not mediated by ovarian hormones
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10:15 AM – 12:15 PM
(858.2) Identification of Disease-relevant, Sex-based Proteomic Differences in iPSC-derived Vascular Smooth Muscle
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10:15 AM – 12:15 PM
(858.3) RNA-Seq Analysis Revealed Sex Differences in Pulmonary Microvascular Endothelial Cells in the Response to Hypoxia
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10:15 AM – 12:15 PM
(858.4) Loss of Female Sex Hormones Does Not Further Elevate Blood Pressure in Obese Female Mice but Preserves the Contribution of Leptin to Hypertension
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10:15 AM – 12:15 PM
(858.5) Uncovering the Effects of Estrogen in an iPSC Derived-Vascular Smooth Muscle Model of Marfan Syndrome
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10:15 AM – 12:15 PM
(858.6) In vivo arterial stiffness, but not isolated artery endothelial function, varies with the mouse estrus cycle
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10:15 AM – 12:15 PM
(858.7) Chronic Pressure Overload and Ovariectomy Alters the Regulation of Cardiac Fibrosis in a Chamber-Specific Manner in Yucatan Mini-Swine
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10:15 AM – 12:15 PM
(858.8) Individualized Estrogen Dosing in Women Undergoing Premenopausal Bilateral Oophorectomy
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10:15 AM – 12:15 PM
(858.9) Impact of Estrogen and Hormonal Birth Control on Vascular Function in Premenopausal Women with Type 1 Diabetes
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10:15 AM – 12:15 PM
(859.1) IL17 administration in the Absence of T cells Results in Hypertension, NK cell Activation, and Reduced Pup Weight at Birth, but No Changes in Blood Pressure or Weight at Maturation of Offspring
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10:15 AM – 12:15 PM
(859.2) Difference in Blood Pressure Measurements in Pregnant Women when using the Gold Standard Method versus Clinical Measurements
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10:15 AM – 12:15 PM
(859.3) The Role of B Cells in Mediating Hypertension in Preeclampsia or COVID-19 Infection During Pregnancy
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10:15 AM – 12:15 PM
(859.4) Effects of pharmacologic interventions on hypertension attenuation and growth factors in animal model
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10:15 AM – 12:15 PM
(860.1) MicroRNA-21 Genetic Ablation Exacerbates Insulin Signaling Dysregulation in Hyperandrogenemic Female Mice
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10:15 AM – 12:15 PM
(860.2) Differences in Outcomes in Obese (≥30), Morbidly Obese (≥40), and Super Morbidly Obese (≥50) Pregnancies
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10:15 AM – 12:15 PM
(860.3) Arginine Vasopressin is not elevated in Early Pregnancy Loss
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10:15 AM – 12:15 PM
(860.4) Elevated Urinary Arginine Vasopressin Concentrations during Preeclamptic Pregnancies do not Persist Postpartum
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10:15 AM – 12:15 PM
(860.5) Development and Utility of a Novel Intergenerational Health Knowledgebase
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10:15 AM – 12:15 PM
(860.6) Effects of 5-hydroxytryptophan on Glucose Tolerance and Lactation in Dairy Cows
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10:15 AM – 12:15 PM
(860.7) Maternal undernourishment stimulates fetuin-B and impairs placental development
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10:15 AM – 12:15 PM
(861.1) Linoleic Acid Induced Angiopoietin-Like Protein 4 Impairs Skeletal Muscle Differentiation
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10:15 AM – 12:15 PM
(861.2) Implication of New identified Nicotine regulated genes in diabetic cardiomyopathy
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10:15 AM – 12:15 PM
(861.3) Catestatin regulates core bioenergetic and metabolic functions of the myocardium
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10:15 AM – 12:15 PM
(861.4) Sexually Dimorphic Effects of Nociceptor LKB1 on Mitochondrial Metabolism and Mechanical Allodynia After Fasting
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10:15 AM – 12:15 PM
(861.5) Alcoholic fatty liver is blunted by rFGF21 administration in mice lacking adipose FGFR1: the role of FGF21 in PPARα-mediated regulation of adipose tissue mass
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10:15 AM – 12:15 PM
(861.6) Increased Insulin Resistance in Male Hepatic Androgen Receptor Knockout Mice Fed High Fructose Diet
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10:15 AM – 12:15 PM
(861.7) Increased Insulin Resistance in 10-month compared to 5-month Old Male Hepatic Androgen Receptor Knockout Mice
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10:15 AM – 12:15 PM
(861.8) High Fat Diet and High Fructose Diet-fed Male and Female Liv-ARKO Mice Displayed Impair Glucose-Stimulated Insulin Secretion
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10:15 AM – 12:15 PM
(861.9) NUCLEAR PARATHYROID HORMONE-RELATED PROTEIN IS NECESSARY FOR PITUITARY SOMATOTROPHS AND GROWTH HORMONE PRODUCTION Waleed J. Hashmi1, Noriko Kantake2, Shiu Yuan2,3, Ibiaghani Max Harry2,3, Nathan K. Hoggard1, Alex H.Fishbach2, Ramiro E. Toribio4, Thomas J. Rosol2,3, Department of Biomedical Sciences, Translation Biomedical Sciences Program, Ohio University, Athens, 45701, OH1, Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University2, Department of Biological Sciences, Molecular and Cellular Biology Program, Ohio University, Athens, 45701, OH3, Department of Veterinary Clinical Sciences, Ohio State University, Columbus, Ohio 432104
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10:15 AM – 12:15 PM
(862.1) Obesity exacerbates SARS-CoV-2 infection in K18-hACE2 mice
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10:15 AM – 12:15 PM
(862.2) Maternal Exercise May Improve Metabolic Outcomes in Offspring in Mice
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10:15 AM – 12:15 PM
(862.3) Social Isolation Influences Endocrine and Metabolic Parameters in Female Mice Depending on Estrous State
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10:15 AM – 12:15 PM
(862.4) Cortisol Receptor Sensitivity as a Risk Factor for Depression
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10:15 AM – 12:15 PM
(862.5) Rescue effects of insulin on the cytotoxic effects of bitter melon extract in the human breast cancer cells.
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10:15 AM – 12:15 PM
(862.6) Glucocorticoid Receptor Beta as a Contributor to Prostate Cancer Growth and Migration
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10:15 AM – 12:15 PM
(863.1) Adult mouse kidney stem cell-derived exosomes navigate nephron repair and regeneration in aged mice
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10:15 AM – 12:15 PM
(863.2) Endothelin-1 Receptor B (ETB) Deficient Rats Fed High Salt Diet Display Differential Mitochondria-Related Gene Expression in the Kidney Cortex and Outer Medulla
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10:15 AM – 12:15 PM
(863.3) Eplerenone-induced natriuresis and hyperkalemia in mice lacking aldosterone results from aldosterone-independent mineralocorticoid receptor occupancy
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10:15 AM – 12:15 PM
(863.4) New Insights into Juxtaglomerular Cells via Single-Cell RNA-Sequencing
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10:15 AM – 12:15 PM
(863.5) Role of β-Arrestin2 as a Regulator of Fluid Homeostasis and Blood Pressure
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10:15 AM – 12:15 PM
(864.1) Long-term Gut Microbiota Depletion Exacerbates Hypertension and Renal Injury in an Experimental Model of Autoimmune Disease
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10:15 AM – 12:15 PM
(864.2) Gut microbiota depletion with antibiotics enhances fructose induced salt-sensitive hypertension in normal rats
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10:15 AM – 12:15 PM
(864.3) Obstructive Sleep Apnea Induced Gut Dysbiosis Stimulates a Proinflammatory Response that Promotes Neuroinflammation and Hypertension Sriram Ayyaswamy, Bojun Zhang, Huanan Shi, Sharon Phillips, Robert Bryan and David Durgan Baylor College of Medicine, Department of Anesthesiology, Houston, Texas, United States
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10:15 AM – 12:15 PM
(864.4) Beyond the Gastrointestinal Tract: Sex-Specific Skin Microbiota Are Associated With Hypertension in Rats With Genetic Disparities
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10:15 AM – 12:15 PM
(865.1) The Pandemic Effects on the Microbiome of Infants in the Neonatal Intensive Care Unit (NICU)
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10:15 AM – 12:15 PM
(865.2) Gut Microbial and Metabolic Signatures are Altered in Adolescents with Type 1 Diabetes
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10:15 AM – 12:15 PM
(865.3) Characterizing the Real-Time Endogenous Methane Release in a Rat for 26-days: Effect of Diets, Fasting, and Ethanol Consumption Across Different Time Scales
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10:15 AM – 12:15 PM
(865.4) Microbiome: A Discrete Influencer of Running Behavior?
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10:15 AM – 12:15 PM
(865.7) Investigating the Link Between the Gut Microbiome and Epilepsy in Zebrafish
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10:15 AM – 12:15 PM
(865.8) Global metagenomics analyses demonstrate metformin-induced changes in the gut mycobiome in subjects with type 2 diabetes
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10:15 AM – 12:15 PM
(865.9) Dysbiosis in the Mouse Esophagus Caused by CaSR Deletion
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10:15 AM – 12:15 PM
(866.1) Dietary Tryptophan-Lactobacillus rhamnosus GG Interactions Modify Intestinal Differentiation and Function
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10:15 AM – 12:15 PM
(866.2) Dietary Oligosaccharides Differentially Modulate Microbiome, Enteric Glia, and Epithelial Barrier Function in the Neonatal Jejunum and Colon
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10:15 AM – 12:15 PM
(866.3) Effects of Prebiotic Fructooligosaccharides on Cytokine and Tight Junction Protein Expression in Cultured Intestinal Epithelial Cells
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10:15 AM – 12:15 PM
(867.1) Wnt signaling promotes IL-33 expression in the colonic epithelium
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10:15 AM – 12:15 PM
(867.4) Loss of Chloride Transporter DRA Triggers Interleukin-33 Secretion from Colonocytes to drive Type 2 Lamina Propria Lymphocyte Expansion
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10:15 AM – 12:15 PM
(867.5) Rotavirus infection elicits host responses and amplifies viral replication via P2Y1 purinergic signaling
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10:15 AM – 12:15 PM
(867.6) Type I interferon co-stimulation enhances γδ intraepithelial lymphocyte IFNγ production
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10:15 AM – 12:15 PM
(867.7) Klebsiella pneumoniae Cross-feeds Clostridioides difficile and Enhances Colonic Pro-inflammatory Responses
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10:15 AM – 12:15 PM
(868.1) The long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury
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10:15 AM – 12:15 PM
(868.2) Desmosome Dysregulation and MLC Phosphorylation Contribute to Loss of Barrier Integrity in DRA KO mice
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10:15 AM – 12:15 PM
(868.3) Identification and characterization of the domain that mediates actin binding and directs basal and TNF-induced myosin light chain kinase 1 (MLCK1) recruitment to the perijunctional actomyosin ring
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10:15 AM – 12:15 PM
(868.4) N6-Methyladenosine (m6A) Modifies Regenerative Transcripts in the Intestinal Epithelium
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10:15 AM – 12:15 PM
(868.5) ErbB3 Promotes Intestinal Barrier Function and Expression of the Tight Junctional Protein Pmp22
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10:15 AM – 12:15 PM
(869.1) Loss of γδ intraepithelial lymphocytes and reduced immunosurveillance of the epithelial barrier precedes the onset of Crohn’s disease-like ileitis
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10:15 AM – 12:15 PM
(869.2) High Autophagic Vesicle Content Identifies a Novel Slow-cycling Esophageal Basal Cell Population with Stem-like Properties
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10:15 AM – 12:15 PM
(869.3) Bacteria-Derived Hypoxanthine Accelerates Gastrointestinal Transit
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10:15 AM – 12:15 PM
(869.4) Dietary Indole-3-Carbinol Supplementation Restores Epithelial Abnormalities in SAMP1/YitFc Mouse Model of Ileitis
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10:15 AM – 12:15 PM
(869.5) Microbiota-induced expansion of the intraepithelial lymphocyte (IEL) compartment results in an altered bioenergetic profile and reduced IFNγ production in γδ IELs
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10:15 AM – 12:15 PM
(870.1) High resolution retrograde tracing, morphological analysis, RNA sequencing and differential expression analysis of identified vagal afferent neurons innervating the muscle or mucosa in 3 different stomach regions in the rat
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10:15 AM – 12:15 PM
(870.2) Cell type specificity on integrin α2 mediated functions in pancreatic cancer
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10:15 AM – 12:15 PM
(870.3) Activation of dorsal motor nucleus cholinergic neurons ameliorates the severity of acute pancreatitis
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10:15 AM – 12:15 PM
(871.1) Wnt Signaling Inhibition Induces Lateral Lumens in Enteroids
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10:15 AM – 12:15 PM
(871.2) Examination of the Interplay between Membrane Tension and the Tight Junction Protein, ZO-1
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10:15 AM – 12:15 PM
(871.3) Epithelial monolayer development and tight junction assembly on nanopillar arrays
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10:15 AM – 12:15 PM
(871.4) Abnormal transporter and tight junction protein expression in environmental enteric dysfunction
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10:15 AM – 12:15 PM
(872.1) Vitamin D Receptor Activation Exerts Anti-Secretory Actions In Colonic Epithelial Cells
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10:15 AM – 12:15 PM
(873.1) Detection of prohibited growth factors (GFs) in doping control: serum concentration ranges in a reference population of athletes
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10:15 AM – 12:15 PM
(874.1) IL-10 Attenuates ER-Stress Induced Apoptosis in Doxorubicin Treated Cardiomyocytes
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10:15 AM – 12:15 PM
(874.2) Probiotics Play a Role in Alleviating Bile Acid (BA)-induced Apoptosis and Oxidative Stress in Human Colonic T84 Cells
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10:15 AM – 12:15 PM
(875.1) Erythropoietin M2 macrophage Signaling Promotes Schwann Cells Clearance and Functional Recovery Following Peripheral Nerve Injury
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10:15 AM – 12:15 PM
(875.2) Enhancing Membrane Repair in Neuronal Cell Types as a Potential Therapeutic for Neurodegenerative Diseases
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10:15 AM – 12:15 PM
(875.3) Sleep Deficits, Repetitive Behaviors, and Increased Slow Gamma Power in an Ank3 Mouse Model of Epilepsy-Mood Disorder Comorbidity
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10:15 AM – 12:15 PM
(875.4) Changes in TRPV4, AQP1, and AQP4 in a Genetic Model of Hydrocephalus Treated with a TRPV4 Antagonist
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10:15 AM – 12:15 PM
(875.5) Single-Cell Sequencing in the Genetic Model of Mitochondrial Dysfunction Reveals Heterogeneity of Lung Endothelial Cells and Novel Targets in Pulmonary Hypertension
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10:15 AM – 12:15 PM
(875.6) Ephrin Ligands are Upregulated in the Saliva of SARS-CoV-2 Infected Patients
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10:15 AM – 12:15 PM
(875.7) Ruxolitinib Prevents Ventilator Induced Diaphragm Dysfunction
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10:15 AM – 12:15 PM
(875.8) Inflammatory Activation and Nitric Oxide Oxidation in Exertional Dyspnea in Southwest Asia Deployed Military Veterans
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10:15 AM – 12:15 PM
(875.9) Mitochondrial PKD Activates Mitochondrial Fission and Proliferative Signaling in Cardiac Fibroblasts
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10:15 AM – 12:15 PM
(876.1) Identification of Signaling and Functional Adaptations of Hematopoietic Stem/Progenitor Cells via Generation of a Low Oxygen Landscape
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10:15 AM – 12:15 PM
(876.2) Circulating hematopoietic stem cells (cHSC) in elite athletes: an antidoping perspective
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10:15 AM – 12:15 PM
(876.3) Calmodulin availability regulates basal autophagy
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10:15 AM – 12:15 PM
(876.4) Effect of High Glucose and Salinity on Embryological Development of Zebrafish, Brachyodanio rerio
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10:15 AM – 12:15 PM
(876.5) Mitochondrial Transfer Between Mesenchymal Stem Cells and Cardiac H9c2 Cells
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10:15 AM – 12:15 PM
(876.6) Effects on Endothelin-1 on Irisin Production By Myocytes Derived From C2C12 Cells
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10:15 AM – 12:15 PM
(877.1) Role of aerobic exercise training on tumor-infiltrated immune cells
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10:15 AM – 12:15 PM
(877.2) Pathophysiological role of NNAT in ER+ breast cancer
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10:15 AM – 12:15 PM
(877.3) May Chelated Iron Be Pro-Inflammatory?
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10:15 AM – 12:15 PM
(878.1) The Effects of Vaping on Human Esophageal Keratinocytes
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10:15 AM – 12:15 PM
(878.2) A new β2 integrin activation reporter mouse reveals localized intra- and extra-vascular neutrophil integrin activation in vivo
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10:15 AM – 12:15 PM
(878.3) Does Macrophage Stimulation by CCL5 Alter Melanoma Migratory Behavior?
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10:15 AM – 12:15 PM
(879.1) Dysregulated Mitochondrial Respiration Occurs With Aging
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10:15 AM – 12:15 PM
(879.2) Substrate-Dependent Differential Regulation of Mitochondrial Bioenergetics and ROS emission in the Heart and Kidney Cortex and Outer Medulla
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10:15 AM – 12:15 PM
(879.3) Diurnal Differences in Mitochondrial Bioenergetics is Lost in Bmal1 Knockout Rats
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10:15 AM – 12:15 PM
(879.4) Depolarized Mitochondrial Membrane Potential and Protection with Duroquinone in Isolated Perfused Lungs from Rats Exposed to Hyperoxia
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10:15 AM – 12:15 PM
(879.5) Reverse Electron Transfer is a More Dominant Source of Mitochondrial ROS Production in the Heart and Kidney Outer Medulla than in the Kidney Cortex
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10:15 AM – 12:15 PM
(879.6) Comparative analysis of mitochondrial CRC in permeabilized cells and isolated cell mitochondria
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10:15 AM – 12:15 PM
(879.7) Peroxiredoxin 6 suppresses erastin-induced ferroptosis in lung endothelial cells
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10:15 AM – 12:15 PM
(879.8) Exercise mimicry: Characterization of nutraceutical agents that may contribute to mitochondrial homeostasis in skeletal muscle
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10:15 AM – 12:15 PM
(879.9) A Reduction in Tafazzin Decreases Mitochondrial Function in C2C12 Myotubes
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10:15 AM – 12:15 PM
(880.1) The impact of maternal dietary deficiencies in folic acid and choline on offspring neuronal function after hypoxia
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10:15 AM – 12:15 PM
(880.2) Cerebral Ischemic Reperfusion Increases Autotaxin Expression Elevating Brain Endothelial Permeability
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10:15 AM – 12:15 PM
(880.3) Sleep Apnea and Kidney Disease: The Role of Hypoxia and Lysyl Oxidase
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10:15 AM – 12:15 PM
(880.4) Studies on the function of myeloid-derived Neuropilin-1 in glioma: a focus on tumor hypoxia
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10:15 AM – 12:15 PM
(881.1) The Role of Skeletal Muscle Intrinsic Clock in the Development and Progression of Cancer Cachexia
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10:15 AM – 12:15 PM
(881.2) Chemotherapy Drugs Induce Cachexia and Alter Muscle Protein Metabolism
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10:15 AM – 12:15 PM
(881.3) 4E-BP1/2 Deletion Enhances mRNA Cap-binding Complex Assembly and Protein Synthesis in Immobilized Skeletal Muscle But is Not Sufficient to Prevent Muscle Atrophy
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10:15 AM – 12:15 PM
(881.4) Impaired Proteostasis, not Protein Synthesis, Limits Recovery of Aged Skeletal Muscle After Disuse Atrophy
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10:15 AM – 12:15 PM
(881.5) Hyperphosphatemia Contributes to Skeletal Muscle Atrophy in the Absence and Presence of Chronic Kidney Disease
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10:15 AM – 12:15 PM
(881.6) Identification and Characterization TSSK6 Activating Co-chaperone (TSACC) in Skeletal Muscle
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10:15 AM – 12:15 PM
(881.7) Overexpression of Multiple E3 Ubiquitin Ligases in Gastrocnemius Muscles from Mice
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10:15 AM – 12:15 PM
(881.8) Identification and Characterization of Calcium Binding and Coiled Coil Domain 1 (Calcoco1) in Skeletal Muscle
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10:15 AM – 12:15 PM
(881.9) Schwann Cell Derived Signals Enhance AChR Clustering in C2C12 Myotubes
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10:15 AM – 12:15 PM
(882.1) Skeletal Muscle Myofibers are a Major Source of Extracellular Vesicles Ex Vivo and In Vivo
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10:15 AM – 12:15 PM
(882.2) Combined transcriptomic, proteomic and synthesis profiling reveal distinct proteostatic signatures for skeletal muscle of adult and old mice
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10:15 AM – 12:15 PM
(882.3) Ethanol Shifts Myoblast Bioenergetic Phenotype: Implications for Muscle Regeneration
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10:15 AM – 12:15 PM
(882.4) Mechanotherapy does not Enhance Recovery Following Muscle Disuse Atrophy in Female Rats
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10:15 AM – 12:15 PM
(882.5) Compromised membrane repair in muscle cells from GNE myopathy patients
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10:15 AM – 12:15 PM
(882.6) Enhanced Isolation of Single Myofibers in Flexor Digitorum Brevis Dissociation
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10:15 AM – 12:15 PM
(882.7) Identification of protein markers for skeletal muscle-derived extracellular vesicles (SkM-EVs) by quantitative proteomics reveals how SkM-EVs function in vivo
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10:15 AM – 12:15 PM
(882.8) PGE2 and WNT3a Promote Skeletal Muscle Regeneration after Barium Chloride Damage In-vitro
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10:15 AM – 12:15 PM
(883.1) Nicotine Alters cAMP Signaling in Arterial Myocytes
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10:15 AM – 12:15 PM
(883.2) The Role of Sex in the Effects of Cigarette Smoke in Vascular Smooth Muscle Cells
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10:15 AM – 12:15 PM
(883.3) Lipid phosphate phosphatase-3 dysfunction exaggerates neointimal hyperplasia following diabetic vascular injury
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10:15 AM – 12:15 PM
(883.4) Efficacy Assessment and Mechanism Exploration of Haptoglobin Phenotyping and Peptide Supplementation Strategy for Restenosis
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10:15 AM – 12:15 PM
(883.5) Protease-Activated Receptor-2 Differentially Regulates Vascular Smooth Muscle Cell Proliferation in Cyclic AMP-Dependent Protein Kinase/Phosphoinositide 3-Kinase-Dependent Manner
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10:15 AM – 12:15 PM
(883.6) The Role of FXR1 and Senescence in Vascular Biology and Intimal Hyperplasia
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10:15 AM – 12:15 PM
(884.1) Sex Differences in Skeletal Muscle Force Production, Fatiguability and Recovery in Slow and Fast Twitch Muscles
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10:15 AM – 12:15 PM
(885.1) Assessment of Skeletal Muscle Oxygenation during Exercise in Patients with Peripheral Artery Disease Using Near Infrared Spectroscopy: Impact of Skin Color and Adipose Tissue Thickness
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10:15 AM – 12:15 PM
(885.2) Spectral Analysis of Resting Near-Infrared Spectroscopy Shows Preserved Endothelial Function after Aerobic Training Exercise in Chronic Kidney Disease
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10:15 AM – 12:15 PM
(885.3) Home-Based Leg Heat Therapy Does Not Improve Vascular Function in Patients with Symptomatic Peripheral Artery Disease
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10:15 AM – 12:15 PM
(885.4) Impact of O2 Availability on Convective and Diffusive O2 Transport and Skeletal Muscle Intracellular PO2 at VO2max
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10:15 AM – 12:15 PM
(885.5) Vascular and Skeletal Muscle Remodeling: Beyond Physical Inactivity.
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10:15 AM – 12:15 PM
(885.6) Myostatin Deletion Preserves Cardio-Metabolic Function in Type 1 diabetes
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10:15 AM – 12:15 PM
(885.7) Investigation into the Role of the Skeletal Muscle BBSome in Insulin Sensitivity
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10:15 AM – 12:15 PM
(885.8) Do Racial Differences Exist in Mechanoreflex Sensitivity in Young Healthy Males?
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10:15 AM – 12:15 PM
(885.9) Intracellular PO2 Does Not Limit Skeletal Muscle Bioenergetics During Fatiguing Contractions In Vivo
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10:15 AM – 12:15 PM
(886.1) Effects of Low Level Laser Therapy on Tendinopathies: A Systematic Literature Review
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10:15 AM – 12:15 PM
(886.2) The combination of NRF1 and Nrf2 activators in myoblasts stimulate mechanisms of proteostasis without changes in mitochondrial respiration
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10:15 AM – 12:15 PM
(886.3) Characterization of CARM1 Inhibition in Skeletal Muscle
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10:15 AM – 12:15 PM
(886.4) Role of apoptosis and autophagy in masseter muscle atrophy evoked by Botulinum Toxin injection
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10:15 AM – 12:15 PM
(886.5) Diet and Exercise Restores Muscle Fiber Phenotype Following Long Term High Fat/High Sugar Diet Yet mRNA Expression Remains Unchanged
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10:15 AM – 12:15 PM
(886.6) 17α-Estradiol Mitigates the Negative Effects of High-Fat Feeding in Both Male and Female Mice
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10:15 AM – 12:15 PM
(886.7) Evaluation of A Muscle Damage Marker Titin N-fragment in Human Skin Interstitial Fluid Using Intradermal Microdialysis
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10:15 AM – 12:15 PM
(886.8) Intrinsic Mitochondrial Function Impacts the Outcomes of Metformin Treatment on Skeletal Muscle Mitochondrial Morphology in Aged Rat
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10:15 AM – 12:15 PM
(886.9) Botulinum toxin injection in masseter muscle evokes musculoskeletal impairment of the masticatory system
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10:15 AM – 12:15 PM
(887.1) Melanoma Impairs Mouse Heart Function Which Short-Term Exercise Cannot Restore
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10:15 AM – 12:15 PM
(887.2) Response of Subsarcolemmal and Intermyofibrillar Mitochondria to Exercise and Doxorubicin-Induced Cardiotoxicity
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10:15 AM – 12:15 PM
(887.3) Exercise Preconditioning Attenuates Doxorubicin-induced Diaphragm Contractile Dysfunction Independent of Phrenic Nerve-stimulated Force Production
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10:15 AM – 12:15 PM
(887.4) Exercise Alters Ceramide Metabolism in Melanoma
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10:15 AM – 12:15 PM
(887.5) Exercise Preconditioning Alters Markers of Cellular Senescence and Prevents DOX-Induced Cardiorespiratory Dysfunction
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10:15 AM – 12:15 PM
(887.6) Short-duration Aerobic Exercise Improves Chemotherapy Induced Physical Dysfunction in Mice
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10:15 AM – 12:15 PM
(887.7) Effects of Exercise on Aortic Stiffness Associated with 5-Flurouracil in Rats
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10:15 AM – 12:15 PM
(887.8) Effects of contraction and feeding on skeletal muscle protein synthesis during the initiation of cachexia
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10:15 AM – 12:15 PM
(887.9) Acute exercise in 5-Fluorouracil cardiotoxicity: Effects on cardiac function and reverse phase protein analysis
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10:15 AM – 12:15 PM
(888.1) Caffeine Augments the Lactate and Interleukin-6 Response to Moderate-Intensity Exercise in Men But Not Women
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10:15 AM – 12:15 PM
(888.2) Exaggerated Activities of P2X3 and ASIC3 Signaling Pathway in Muscle Afferent Following Himblimb Muscle Ischemia-Reperfusion
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10:15 AM – 12:15 PM
(888.3) Dysregulation of Skeletal Muscle Mitochondrial Turnover and Dynamics Occurs During Late Symptomatic Stages of Spinal Muscular Atrophy
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10:15 AM – 12:15 PM
(888.4) The Role of ATF5 in Mitochondrial Maintenance, Biogenesis and UPRmt Signaling Following Acute Exercise in Skeletal Muscle
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10:15 AM – 12:15 PM
(888.5) Comparison of Excess Post-exercise Oxygen Consumption between Continuous, Interval, and Accumulated Workout with Equalized Exercise Volume in Healthy Women
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10:15 AM – 12:15 PM
(888.6) Exercise modulates estrogen receptors in a rat animal model of endometriosis
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10:15 AM – 12:15 PM
(888.7) A Practical Application of Blood Flow Restriction Exercise
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10:15 AM – 12:15 PM
(888.8) Effects of Maximal Exercise on Central and Peripheral Arterial Stiffness in Adults with and without Intellectual and Developmental Disabilities
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10:15 AM – 12:15 PM
(888.9) Pre-fatiguing Isometric Quadriceps Exercise Impairs Contralateral Quadriceps W’ During All-out and Not Target Torque Time to Task Failure Exercise
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10:15 AM – 12:15 PM
(889.1) ALDH2 Deficiency Enhances Mechanical Overload-Induced Protein Synthesis but Not Muscle Mass
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10:15 AM – 12:15 PM
(889.2) Monitoring of hemoglobin and erythropoiesis-related mRNA in athletes and patients Dried Blood Spots
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10:15 AM – 12:15 PM
(889.3) High-Density Lipoprotein is Independently Associated with Muscle Mitochondrial Function in Healthy Humans
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10:15 AM – 12:15 PM
(889.4) Metabolic Cooperation Between Adipose Tissue and Skeletal Muscle Mediates the Prevention of NAFLD Through Aerobic Physical Exercise
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10:15 AM – 12:15 PM
(889.5) Effect of Lactate Intake on Total Fat Mass and Resting Metabolic Rate in Mice
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10:15 AM – 12:15 PM
(889.6) The Impact of Varying Caffeine-Induced Contractile Activity on Metabolic Enzyme Activity
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10:15 AM – 12:15 PM
(889.7) Does Inosine Monophosphate Formation Facilitate the Bioenergetic Response to Incremental Contractions in Human Skeletal Muscle In Vivo?
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10:15 AM – 12:15 PM
(890.1) Protein Kinase C Epsilon Contributes to the Exaggerated Mechanoreflex in Rats with Heart Failure
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10:15 AM – 12:15 PM
(890.2) Intra and inter-day reproducibility of the functional sympatholysis protocol during rhythmic handgrip exercise in healthy humans
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10:15 AM – 12:15 PM
(890.3) Pro-inflammatory Cytokine IL-1β Contributes to the Exaggerated Exercise Pressor Reflex in UC, Davis-Type 2 Diabetes Mellitus Rats
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10:15 AM – 12:15 PM
(890.4) Baroreceptor Deafferentation Impairs the Exercise Training -and Drug Treatment-Induced Adaptations in a Hypertensive Model of Menopause
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10:15 AM – 12:15 PM
(890.5) The Effect of Aerobic Exercise Training on Sympathetic Nervous Activity and Vascular Compliance in Patients with Chronic Kidney Disease
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10:15 AM – 12:15 PM
(890.6) Arterial Baroreceptor Denervation Enhances Muscle Metaboreflex Induced Increases in Effective Arterial Elastance Without Worsening Stoke Work During Dynamic Exercise in Heart Failure
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10:15 AM – 12:15 PM
(890.7) Rapid Adjustments to Autonomic Control of Cardiac Rhythm at the Onset of Exercise in Healthy Young Adults
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10:15 AM – 12:15 PM
(891.1) Site-specific regulation of emotional stress responses along the rostrocaudal axis of the insular cortex in rats
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10:15 AM – 12:15 PM
(891.2) Muscle Sympathetic Nerve Reactivity to Trier Social Stress Test
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10:15 AM – 12:15 PM
(891.3) A Potential Link Between Negative Affective Responsivity to Daily Stress and Blood Pressure Reactivity to Acute Stress in College-Aged Adults
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10:15 AM – 12:15 PM
(891.4) Neurocognitive Capabilities and Physiological Responses to Cognitive Stress as well as General Health and Fitness Measurements in Competitive Gamers versus Non-Gamers
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10:15 AM – 12:15 PM
(891.5) The Stress Hormone ACTH Causes a Prolonged Reduction in Heart Rate Variability
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10:15 AM – 12:15 PM
(892.1) Activation of satellite glia in stellate ganglia from chronic heart failure rats
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10:15 AM – 12:15 PM
(892.2) Skeletal Muscle Oxygen Delivery and Utilization during Exercise in Heart Failure with Preserved Ejection Fraction: Role of Sympathetic (α-adrenergic) Vasoconstriction
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10:15 AM – 12:15 PM
(892.3) Catecholaminergic RVLM C1 neurons mediates heart failure decompensation and mortality during salt loading
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10:15 AM – 12:15 PM
(892.4) Factors Influencing Muscle Sympathetic Nerve Activity in Human Heart Failure
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10:15 AM – 12:15 PM
(893.1) Renal Sympathetic Nerve Activity Responses to Hypoxia and Hypercapnia in Rats Exposed to Chronic Intermittent Hypoxia
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10:15 AM – 12:15 PM
(893.2) Contribution of Adenosine A2A Receptors in the Rostral Ventrolateral Medulla to Acupuncture Modulation of Hypertension
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10:15 AM – 12:15 PM
(893.3) Uncovering Anti-Arrhythmic Potential of Stellate Ganglion Purinergic Receptors
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10:15 AM – 12:15 PM
(893.4) ACE2 Ubiquitination in the Paraventricular Nucleus of the Hypothalamus Contributes to Angiotensin-II-Induced Hypertension in Mice
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10:15 AM – 12:15 PM
(893.5) Hypothalamic Corticotrophin Releasing Hormone Signal Contributes to Elevated Sympathetic Outflow in primary hypertension
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10:15 AM – 12:15 PM
(893.6) Deletion of the Transient Receptor Vanilloid-1 (TRPV1) Channel in Rats Attenuates 2-Kidney-1-Clip Hypertension
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10:15 AM – 12:15 PM
(893.7) SK Channel Dysfunction in the Hypothalamic Paraventricular Nucleus Contributes to Sympathoexcitation in Dahl Salt-Sensitive Rats
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10:15 AM – 12:15 PM
(893.8) Mental Stress Pressor Response and Post-Stress Aortic Wave Reflection
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10:15 AM – 12:15 PM
(895.1) Hypoxemia Augments the Local Metabolic Error Signal and Improves Coronary Pressure-Flow Autoregulation
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10:15 AM – 12:15 PM
(895.2) Age-related impairment in dynamic cerebrovascular compliance responses to standing despite preserved cerebrovascular resistance responses
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10:15 AM – 12:15 PM
(896.1) Inverse Neurovascular Coupling Contributes to Vasopressin Neuronal Activation in Response to Systemic Homeostatic Challenge
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10:15 AM – 12:15 PM
(896.2) Effects of K252a and K252b on CIH induced Changes in mEPSCs from PVN-projecting MnPO
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10:15 AM – 12:15 PM
(896.3) Changes in PVN Neurons after Low-Frequency Acute Optogenetic Stimulation
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10:15 AM – 12:15 PM
(897.1) Opioid-Induced Respiratory Depression (OIRD) in C57BL/6J (B6) Mice is Mitigated by Prefrontal Cortex Neostigmine Administration
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10:15 AM – 12:15 PM
(897.2) Accumulation of pathological Ataxin-7 in the medulla leads to hypoglossal (XII) motor unit pathology
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10:15 AM – 12:15 PM
(897.3) Respiratory Functional and Neuroanatomical Changes in 6-OHDA Model of Parkinson’s Disease Require Tumor Necrosis Factor Alpha Receptor 1
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10:15 AM – 12:15 PM
(897.4) Role of central irisin in the cardiorespiratory and metabolic control of adult rats
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10:15 AM – 12:15 PM
(897.5) Maternal opioids decrease mu-opioid receptor expression in the neonatal preBötzinger Complex
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10:15 AM – 12:15 PM
(897.6) A Neuromodulatory System that Links Opioid-Induced Sedation and Respiratory Depression
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10:15 AM – 12:15 PM
(897.7) Dissecting breathing control dysregulation in neonatal sepsis
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10:15 AM – 12:15 PM
(898.1) Vitamin D Supplementation Partially Rescues Breathing Deficits in Mecp2 Hemizygous Null Mice, a Model of Rett Syndrome
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10:15 AM – 12:15 PM
(898.2) Restoration of tidal volume after spinal cord injury by hyperbaric oxygen therapy requires both pressure and 100% oxygen
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10:15 AM – 12:15 PM
(898.3) Diaphragm EMG activity during hyperbaric oxygen exposure in spinal injured rats
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10:15 AM – 12:15 PM
(898.4) Weekly Acute Intermittent Hypoxia as a Strategy to Restore Spontaneous Micturition Patterns in Awake Rats with Moderate Contusion SCI: Therapeutic Efficacy and Time Course
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10:15 AM – 12:15 PM
(898.5) Weekly Acute Intermittent Hypoxia Elicits Sustained Beneficial Improvements in Reflex Bladder Function in Rats with Moderate Contusion SCI
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10:15 AM – 12:15 PM
(898.6) Single Nuclear RNA Sequencing Reveals Activation of Neuroinflammation Within the Pre-Bötzinger Complex Following Repeated Seizures
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10:15 AM – 12:15 PM
(898.7) nTS Glutamate Signaling in the Chemoreflex Axis of an Alzheimers Disease Rat Model
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10:15 AM – 12:15 PM
(898.8) Abnormal hypoxic and hypercapnic ventilatory responses in 5XFAD Alzheimer’s disease mice
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10:15 AM – 12:15 PM
(898.9) Mild-to-Moderate Chronic Hypercapnia Impairs Adaptation of Acute CO2/H+ Chemosensitivity but Not Steady-State Ventilation
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10:15 AM – 12:15 PM
(899.1) Pulmonary Endothelial Tau Aggregation After Infection
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10:15 AM – 12:15 PM
(900.2) Plate-Based Respirometry to Assess Zebrafish Embryo Bioenergetics in situ in Changing Environmental Conditions
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10:15 AM – 12:15 PM
(900.3) Insights into the Evolution of Non-shivering Thermogenesis from UCP1 of the Naked Mole Rat (Heterocephalus glaber)
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10:15 AM – 12:15 PM
(900.4) Prolactin Directs Branchial and Intestinal Gene Expression of Solute Transporters and Aquaporins in Mummichog (Fundulus heteroclitus)
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10:15 AM – 12:15 PM
(900.5) Rapid Hypoxia-Induced Upregulation of Glutathione-Related Genes May Protect Elephant Seal Endothelial Cells Against Oxidative Stress
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10:15 AM – 12:15 PM
(900.6) Direct reprogramming of dermal fibroblasts derived from Northern elephant seals into muscle cells
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10:15 AM – 12:15 PM
(901.1) Decreasing tracheal system volume during intermolt development in grasshoppers
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10:15 AM – 12:15 PM
(901.2) Gravidity Impacts Respiratory Function, Tracheal Volume, and Jump Performance in Grasshoppers
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10:15 AM – 12:15 PM
(901.3) Hypoxia Inducible Factor is partially involved in mitochondrial and metabolic responses to hypoxia in rats DEMAREST Maud 1, MARCOUILLER François 1, SOLIZ Jorge 1, JOSEPH Vincent 1 1 Institut universitaire de cardiologie et de pneumologie, Université Laval, Québec.
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10:15 AM – 12:15 PM
(901.4) Central nervous system 5-HT plays a role in ventilatory and arousal responses to hypoxia and hypercapnia in spinal cord injured mice
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10:15 AM – 12:15 PM
(901.5) Resveratrol Reduces Arterial Stiffness and Improves Functional Capacity in Patients with COPD
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10:15 AM – 12:15 PM
(901.6) Weddell seals (Leptonychotes weddellii) respond less to inflammatory stimuli to evade ischemic-reperfusion injury
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10:15 AM – 12:15 PM
(901.7) Pharmacologic Microglial Depletion Disrupts Breathing and Body Temperature Regulation During Torpor in 13-lined Ground Squirrels
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10:15 AM – 12:15 PM
(901.8) The Role of Glutamatergic Signaling in Central Noradrenergic Neurons in Respiratory Control
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10:15 AM – 12:15 PM
(901.9) Examining Vascular Function and Oxidative Stress in Young Individuals with Generalized Anxiety Disorder
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10:15 AM – 12:15 PM
(902.1) Research Handling Effects on Stress Hormones, Blood Parameters, and Heart Rate in Juvenile Northern Elephant Seals (Mirounga angustirostris)
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10:15 AM – 12:15 PM
(902.2) Determining the Dominant Glucocorticoid in the Mexican Axolotl
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10:15 AM – 12:15 PM
(902.3) A Test of Altitude-Related Variation in Aerobic Metabolism of Andean Birds
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10:15 AM – 12:15 PM
(902.4) Thermoregulatory dysfunction in post-weaning congenic corpulent rats
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10:15 AM – 12:15 PM
(902.5) Effect of Black Fly Larva Diet Supplement on Goldfish (Carassius auratus) Reproduction in an Aquaponics System
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10:15 AM – 12:15 PM
(902.6) The Effects of Pyrene on Complex I and Complex II-mediated Respiration in Isolated Skeletal Muscle Mitochondria in the Leopard frog, Rana pipiens
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10:15 AM – 12:15 PM
(903.1) Buoyancy and Hydrostatic Balance in The West Indian Coelacanth Latimeria chalumnae
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10:15 AM – 12:15 PM
(903.2) A New Method for Characterizing Muscle Shortening Deactivation
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10:15 AM – 12:15 PM
(903.3) Hypoxia Decreases Jump Rate and Increases Lactate Production in Late-Stage Grasshoppers
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10:15 AM – 12:15 PM
(903.4) Fine-regulation of myosin relaxed states in vertebrate muscle
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10:15 AM – 12:15 PM
(903.5) In Arctic ground squirrels, diet and torpor alter skeletal muscle relaxation kinetics but not force development
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10:15 AM – 12:15 PM
(903.6) Examining the Plasticity of the Dive Response in Relation to Dive Behavior of Northern Elephant Seals
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10:15 AM – 12:15 PM
(903.7) Mouse Strain Differences in Female Mice Fed a Short-Term Western Diet
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10:15 AM – 12:15 PM
(904.1) Resemblance in Physiological Systems during Phylogeny and Ontogeny
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10:15 AM – 12:15 PM
(904.2) Endocrine and osmotic responses to tidally-changing salinities in Mozambique tilapia, Oreochromis mossambicus
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10:15 AM – 12:15 PM
(904.3) Multiple Freeze-thaw Cycles in Cope’s Gray Treefrog Dryophytes chrysoscelis Reveal Novel Physiological, Biochemical, and Morphological Insights into Vertebrate Freeze Tolerance
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10:15 AM – 12:15 PM
(905.1) Uncovering the neural circuits that drive food odor detection in drosophila
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10:15 AM – 12:15 PM
(905.2) Expression of rhodopsin and opsin in late-stage epigean and hypogean salamander embryos
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10:15 AM – 12:15 PM
(905.3) Improved Hypoxia Tolerance Involves Altered NMDA Receptor Function To Oppose Hyperexcitable Network Output in Bullfrogs
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10:15 AM – 12:15 PM
(905.4) Morphological Description of Olfactory Organ Changes after Acute Nitrite Exposure in Xiphophorus couchianus
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10:15 AM – 12:15 PM
(906.1) Macronutrient Signals for Adaptive Modulation of Intestinal Digestive Enzymes in Two Omnivorous Galliforms
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10:15 AM – 12:15 PM
(907.1) Sperm Competition and Its Effects on the Evolution of Prostatic Acid Phosphatase in Hominids
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10:15 AM – 12:15 PM
(907.2) Sexually Dimorphic Responses to Growth Hormone and Luteinizing Hormone within the Somatotropic and Reproductive Axes of Tilapia
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10:15 AM – 12:15 PM
(907.3) Comparison of Prostate-Specific Transglutaminase Function in the Great Apes
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10:15 AM – 12:15 PM
(907.4) Quantifying Thermal Patterns Across Canine Body and Limbs
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10:15 AM – 12:15 PM
(907.5) Functional Analysis of KLK3/PSA Protease Activity in Primates
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10:15 AM – 12:15 PM
(907.6) Long-term Anesthesia in the Mexican Axolotl Salamander
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10:15 AM – 12:15 PM
(907.7) Calcium Assimilation for Regenerative Purposes in Axolotls
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10:15 AM – 12:15 PM
(907.8) Effects of Aging on Performance and Oxidative Damage
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10:15 AM – 12:15 PM
(924.1) Systematic Review and Meta-analysis of the Anatomical Variants in Renal Vascularization and their Clinical Implication using Anatomical Quality Assurance (AQUA) checklist
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10:15 AM – 12:15 PM
(924.2) Surgical Skills in General Surgery Residency Program: Current Trends and Future Directions
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10:15 AM – 12:15 PM
(924.3) Evaluation of the Number of Goblet Cells in Crypt of Colonic Mucosa Submitted to Experimental Gastric Restriction
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10:15 AM – 12:15 PM
(924.4) Anatomical Study of the Innervation of the Tibialis Anterior Muscle and its Correlation with Miofascial Trigger Points: Preliminary Results
Favorite
10:15 AM – 12:15 PM
(924.5) Anatomical Study of the Innervation of the Fibularis Longus (FL) Muscle and its Correlation with Miofascial Trigger Points: Preliminary Results
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10:15 AM – 12:15 PM
(924.6) Anatomical Substract of the Temporal Muscle Myofascial Trigger Points in Fresh Cadavers
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10:15 AM – 12:15 PM
(924.7) Innervation of Gluteus Medius Muscle and its Relationship with Myofascial Pain
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10:15 AM – 12:15 PM
(924.8) A Cadaveric Analysis of Morphological Variations of Pectoral Girdle Muscles: Axillary Arch and Coexisting Pectoralis Muscle Variations
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10:15 AM – 12:15 PM
(924.9) An Atypical Origin of the Saphenous Nerve and a Variation of the Right Iliacus Muscle: A Case Report
Favorite
10:15 AM – 12:15 PM
(925.1) The vital landmarks of human body (Marma) according to TCAM and its application in Physical medicine and Rehabilitation
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10:15 AM – 12:15 PM
(925.2) A Pilot Anatomy-based Teacher Training Curriculum for Medical Students
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10:15 AM – 12:15 PM
(925.3) Faculty retirements’ impacts on the anatomy educator shortage
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10:15 AM – 12:15 PM
(925.4) Use of Retrieval Practice Data as a Learning Analytics Tool
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10:15 AM – 12:15 PM
(925.5) The Effect of Clinical Anatomy Integration on Medical Student Academic Performance and Learning Approach
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10:15 AM – 12:15 PM
(925.6) Activity Monitoring During the Instruction of Gross Anatomy
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10:15 AM – 12:15 PM
(925.7) Current Status of Graduate Anatomy Education in The State of Ohio
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10:15 AM – 12:15 PM
(925.8) Integrating Clinical Education into the Anatomy Curriculum; The Advantages of Soft Preservation Techniques
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10:15 AM – 12:15 PM
(925.9) Teaching Color-Deficient Medical and Dental Students in Histology: Developing Best Practices and Strategies for Student Success
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10:15 AM – 12:15 PM
(926.1) Defining the Hierarchy of Heterogeneity of Digits in the Expression of Fingerprint White Line Count: Forensic Perspective
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10:15 AM – 12:15 PM
(926.2) Comorbidity of Anemia and Otitis Media in Skeletal Remains
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10:15 AM – 12:15 PM
(926.3) Modified Biocultural Stress Model
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10:15 AM – 12:15 PM
(927.1) Efficacy of Extracorporeal Shockwave Therapy on Knee Osteoarthritis Related Pain and Activities of Daily Living: A Systematic Literature Review
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10:15 AM – 12:15 PM
(927.2) Gross Anatomy of Bifid Xiphoid Process
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10:15 AM – 12:15 PM
(927.3) GRK2, a novel regulator of skeletal development
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10:15 AM – 12:15 PM
(927.4) pQCT Analysis of Cortical Bone in Rats Exposed to High Levels of Cortisol in-utero
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10:15 AM – 12:15 PM
(928.1) AJAP1 Gene Silencing Alters Protein Expression in Epithelial Cells
Favorite
10:15 AM – 12:15 PM
(929.1) Angico Gum suppresses inflammatory responses and maintains tissue integrity through the NO and COX-2 pathway in intestinal mucositis induced by 5-fluorouracil
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10:15 AM – 12:15 PM
(929.2) Epigallocatechin Gallate (EGCG) Mitigates The Effect of Camptothecin-Induced Oxidative Stress on Bone Cancer-like cells (UMR 106-01 BSP) by Inhibiting Apoptosis
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10:15 AM – 12:15 PM
(929.3) Synthesis of A Tetrahydrocannabinol (THC) Analog For Analyzing Cellular Proliferation in Concert With Epigallocatechin Gallate (EGCG) on A Bone-like Cancer Cell Line (UMR 106-01 BSP)
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10:15 AM – 12:15 PM
(929.4) Chronic Obstructive Pulmonary Diseased Human Lung Fibroblasts Secrete Increased Matrix Metalloproteases -12 and -8
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10:15 AM – 12:15 PM
(930.1) The Role of Connexin-43 in Cranial Neural Crest Cell Differentiation
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10:15 AM – 12:15 PM
(930.2) Effect of Zinc in Submandibular Salivary Gland Branching Morphogenesis
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10:15 AM – 12:15 PM
(930.3) Investigating Cell Fate Specification upon Nkx2-1 Loss
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10:15 AM – 12:15 PM
(930.4) Downstream Branches of the Fibroblast Growth Factor Signaling Pathway Act Interdependently to Shape the Face
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10:15 AM – 12:15 PM
(931.1) Anatomical Mechanism for Protecting the Airway in Whales Involves Interlocking the Larynx
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10:15 AM – 12:15 PM
(931.2) The Evolution of Language-Related Long Association Pathways: A Comparative Study Between Humans and Rhesus Macaques
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10:15 AM – 12:15 PM
(932.1) Osteological Correlates of Fascicle Length and Gape in Carnivora
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10:15 AM – 12:15 PM
(932.2) North American River Otters Exhibit Direction Asymmetry in Limb Bone Shape
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10:15 AM – 12:15 PM
(933.1) Highest Resolution MicroCT Scan of the Human Brainstem Reveals Putative Anatomical Basis for Infrequency of Medial Medullary Syndrome
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10:15 AM – 12:15 PM
(933.2) Effectiveness of X-ray in Detecting the Fabella Sesamoid Bone
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10:15 AM – 12:15 PM
(934.1) Levator Palpebrae Superioris: Development, Structure, Variation, and Clinical Implications
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10:15 AM – 12:15 PM
(934.2) TGFβ Induces Changes in Mitochondrial Homeostasis in Skeletal Muscle of Mice with Bone Metastases
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10:15 AM – 12:15 PM
(934.3) Outcome of short-term physiotherapy intervention program on early stage of multiple sclerosis - A case report
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10:15 AM – 12:15 PM
(935.1) Cerebral Vascular Density and Its Possible Correlation with Alzheimer Disease Progression in Elderly Individuals with Rheumatoid Arthritis
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10:15 AM – 12:15 PM
(935.2) Klotho Expression in Aging and Disease
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10:15 AM – 12:15 PM
(935.3) Neurons in the Caudate Nucleus of the Camel and Human: A Comparative Study
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10:15 AM – 12:15 PM
(935.4) Effects of tooth loss on anxiety-like behaviors in Heterocephalus glaber
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10:15 AM – 12:15 PM
(935.5) Quantification of Chlamydia pneumoniae and amyloid plaques within the limbic pathway related to late-onset dementia/Alzheimer’s
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10:15 AM – 12:15 PM
(935.6) Developing a diceCT brain atlas: Comparison of diceCT neuroanatomy and brain histology in a rat model
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10:15 AM – 12:15 PM
(935.7) Expression of Micrornas Mir-126, Mir-133b and Mir-221 Associated With Apoptosis in Rats Submitted to Focal Cerebral Ischemia and Physical Exercise
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10:15 AM – 12:15 PM
(936.1) Structural Heteropolysaccharide Adhesion to the Corneal Glycocalyx
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10:15 AM – 12:15 PM
(936.2) Absence of Gli1 Decreases PDGFRβ Expression Following Ductal Ligation Injury
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10:15 AM – 12:15 PM
(947.1) 3D cardiac calcium imaging of zebrafish revealed doxorubicin-induced cardiotoxicity
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10:15 AM – 12:15 PM
(947.2) Correlation of the pulse rate in horses at the start with the results of endurance ride
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10:15 AM – 12:15 PM
(947.3) Chronic Unpredictable Stress impairs Relaxation Responses to Acetylcholine in Resistance Arteries from Mice
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10:15 AM – 12:15 PM
(947.4) Cardiovascular Fitness Improves Cardiac Interoceptive Accuracy
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10:15 AM – 12:15 PM
(947.5) Pilot Study on the Influence of Race and Sex on beat-to-beat Blood Pressure Variability in Healthy Young Adults
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10:15 AM – 12:15 PM
(947.6) Functional Balance among Middle-aged Adults is a Risk Factor for Cardiovascular Disease
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10:15 AM – 12:15 PM
(947.7) A Critical Role for Pannexin 1 in Heart Failure Induced by Acute and Chronic Isoproterenol Administration
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10:15 AM – 12:15 PM
(947.8) Role of Rho-associated kinase (ROCK) in the different speed of relaxation between pulmonary arteries and mesentery arteries of rats
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10:15 AM – 12:15 PM
(947.9) Perceived Pain is Associated with Cardiovascular Responsiveness During Metaboreflex Activation in Apparently Healthy Young Males and Females
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10:15 AM – 12:15 PM
(948.1) Mitochondrial TOM70 in Hyperoxia-induced Acute Lung Injury
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10:15 AM – 12:15 PM
(948.2) Glucose homeostasis is impaired in Guanylyl Cyclase/Natriuretic Peptide Receptor-A Gene-Knockout and Gene-Duplication Mutant Mice
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10:15 AM – 12:15 PM
(948.3) Head and Neck Cancer-derived Small Extracellular Vesicles Activate TRPV1+ neurons to Mediate Cancer Pain
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10:15 AM – 12:15 PM
(948.4) Astrocyte-to-neuron reprogramming for spinal cord repair
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10:15 AM – 12:15 PM
(948.5) Downregulation of ANO1 activity in PC-9 cells modulated by a new novel candidate TMEMinh001
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10:15 AM – 12:15 PM
(948.6) Bi-directional pH dependency of CALHM1 ion channel
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10:15 AM – 12:15 PM
(948.7) HIF1α and NFκB Regulate Mineralocorticoid Receptor Gene Expression in Aging Human Vascular Smooth Muscle Cells
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10:15 AM – 12:15 PM
(948.8) Exploring additional sleep roles for the PERIOD homolog LIN-42 using the auxin-inducible degradation system in Caenorhabditis elegans
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10:15 AM – 12:15 PM
(948.9) Characterizing the Mechanism of a Conserved G-Protein Coupled Receptor in Caenorhabditis elegans
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10:15 AM – 12:15 PM
(949.1) 1,3-Butanediol Mitigates High-Salt Diet Induced Cognitive Impairment in Aging Mice
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10:15 AM – 12:15 PM
(949.2) Impact of Patterned Feeding of a Palatable Diet on Chronic Alcohol Drinking and Anxiety-Like Behavior in Alcohol-Preferring Rats
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10:15 AM – 12:15 PM
(949.3) Menopause Diminishes Female Protection against Vascular Contributions to Cognitive Impairment and Dementia
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10:15 AM – 12:15 PM
(949.4) Domestic crickets (Acheta domesticus) as an animal model to study Parkinsons disease
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10:15 AM – 12:15 PM
(949.5) Orexin A enhances neuronal synchronization in adult rat hypothalamic culture: A model to study hypothalamic function
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10:15 AM – 12:15 PM
(949.6) Triggering eye movements in mice to understand stable visual perception
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10:15 AM – 12:15 PM
(950.1) Physiological Basis of Adaptation of Yakut Horses to Subarctic Climate
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10:15 AM – 12:15 PM
(950.2) Interspecific Variation in Oxygen-Binding Properties of Scorpion Hemocyanin
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10:15 AM – 12:15 PM
(950.3) Leucocytes are Mass-Invariant in Reptiles Unlike in Endotherms
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10:15 AM – 12:15 PM
(950.4) Tracking the ancestral functions of erythropoietin: neuroprotection amp; mitochondria
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10:15 AM – 12:15 PM
(950.5) Scaling of Antibacterial Immune Defenses in Mammals
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10:15 AM – 12:15 PM
(950.6) Contributions of the rostral vs. middle conchae in temporal countercurrent exchange in the domestic chicken
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10:15 AM – 12:15 PM
(950.7) Comparison of the behavior of hybrids and domestic lambs in the early postnatal period
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10:15 AM – 12:15 PM
(951.1) A microengineered biomimetic model of the placental barrier to study environmental exposures during pregnancy
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10:15 AM – 12:15 PM
(951.2) Chlorine inhalation toxicology-on-a-chip
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10:15 AM – 12:15 PM
(951.3) Kinetics of Plant-derived Heteropolysaccharide Bioabsorption Characterized by Fluorescence-based Microfluidics System
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10:15 AM – 12:15 PM
(951.4) Automated Evaluation of Respiratory Signals to Provide Insight Into Respiratory Drive
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10:15 AM – 12:15 PM
(951.5) A Non-Invasive Method to Estimate Pulmonary Oxygen Transfer Rate
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10:15 AM – 12:15 PM
(952.1) ATP10A has a protective and sex-specific role in lipid metabolism
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10:15 AM – 12:15 PM
(952.2) Characterizing the Therapeutic Potential of the Adropin-GPR19 Signaling Pathway in MAFLD
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10:15 AM – 12:15 PM
(952.3) An Underlying Mechanism by which Hepatic Steatosis Drives the Development of Hypertension
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10:15 AM – 12:15 PM
(952.4) Impact of aerobic fitness status, menstrual cycle phase, and oral contraceptive use on exercise metabolic flexibility
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10:15 AM – 12:15 PM
(952.5) HuR Mediates Thermogenic Metabolism in Brown Adipose Tissue Through Control of Sarco-Endoplasmic Calcium Cycling
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10:15 AM – 12:15 PM
(952.6) Glucose mediates upregulation of Cck expression independent of cAMP signaling
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10:15 AM – 12:15 PM
(952.7) In Vivo Effects of AICAR and Prodrug 39 (P39) on Anabolic Pathways Following Refeeding in Skeletal Muscle
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10:15 AM – 12:15 PM
(952.8) Mitochondrial Uncoupling Decreases Sarcopenic Obesity By Activation of Skeletal Muscle Mitochondrial Quality Control and Attenuated ER Stress
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10:15 AM – 12:15 PM
(952.9) BMI: A Screening Tool Analysis
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10:15 AM – 12:15 PM
(953.1) Voluntary drinking prevents dehydration when following occupational heat stress recommendations
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10:15 AM – 12:15 PM
(953.2) High-intensity, low-volume inspiratory muscle strength training blunts the cardiovascular response to constant load respiratory testing
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10:15 AM – 12:15 PM
(953.3) Assessment of Metabolic Response During High-Intensity Interval Exercise and Resting Vascular and Mitochondrial Function in Recreational CrossFit Participants
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10:15 AM – 12:15 PM
(953.4) Effects of High Frequency Resistance Training on RNA Expression Related to Inflammation: A Case Report
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10:15 AM – 12:15 PM
(953.5) The Effects of Morning vs. Evening Mindfulness Meditation on Sleep, Anxiety, and Decentering: A Pilot Analysis
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10:15 AM – 12:15 PM
(953.6) BPA and BPS increase oxidative stress inducing a decrease in physical fitness and dyslipidemia in young adults
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10:15 AM – 12:15 PM
(953.7) Exercise Responsiveness in Obese Adults
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10:15 AM – 12:15 PM
(953.8) Impact of Intermittent Hypoxia Exposure on Erythropoietin Levels in Older Individuals
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10:15 AM – 12:15 PM
(953.9) Cytokine and Chemokine Release from Immortalised Human Myotubes in Culture: Effect of Contractions and Comparison with Isolated Intact Mature Adult Murine Muscle Fibres
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10:15 AM – 12:15 PM
(954.1) Internalization of Angiotensin-(1-12) in Adult Retinal Pigment Epithelial-19 Cells
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10:15 AM – 12:15 PM
(954.2) Sphingomyelin-enriched extracellular vesicles from hypertensive diabetic mice regulate calcium mobilization and amiloride-sensitive transepithelial current in mouse cortical collecting duct cells
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10:15 AM – 12:15 PM
(955.1) Antibiotics and High-Fat-Diet Induced Gut Inflammation and Impaired Gut Permeability are Improved by Dietary Blueberries Possibly Through NFκB Signaling
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10:15 AM – 12:15 PM
(955.2) The Lasting Effects of COVID-19 on The Progression of Non-Alcoholic Fatty Liver Disease
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10:15 AM – 12:15 PM
(955.3) Characterizing the Luminal Microenvironment of Human Organoids for Studies of Gastric pH Regulation
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10:15 AM – 12:15 PM
(955.4) Human Colonoids Enable the Study of Host-Specific Infectivity and Proteomic Responses to Campylobacter jejuni Infection
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10:15 AM – 12:15 PM
(955.5) Inhalation Exposure to Airborne PM2.5 Induces Integrated Organelle Stress Response in the Liver
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10:15 AM – 12:15 PM
(956.1) What does the Historical Record Say about the Chances of Surviving an Escape from a Disabled Submarine?
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10:15 AM – 12:15 PM
(957.1) Daily E-cigarette Vapor Exposure Does Not Modify Response to 10% Normobaric Hypoxia in Long-Evans Rats
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10:15 AM – 12:15 PM
(957.2) Changes in brain interstitial pH induced by hypoxia versus asphyxia in normothermic or hypothermic newborn pigs: implications for the preclinical study of neonatal hypoxic-ischemic encephalopathy
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10:15 AM – 12:15 PM
(957.3) Genetic and molecular basis of Adaptive and Mal-adaptive excessive erythropoietic responses in the Andean region
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10:15 AM – 12:15 PM
(957.4) Low Serum Erythropoietin Levels are Associated with Fatal COVID-19 Cases at 4,150 meters above sea level
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10:15 AM – 12:15 PM
(957.5) Complex II-linked mitochondrial respiration is upregulated during postnatal development in high-altitude grown mice
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10:15 AM – 12:15 PM
(957.6) Using Caffeine to Enhance the Therapeutic Effects of Respiratory Training After Cervical Spinal Cord Injury
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10:15 AM – 12:15 PM
(957.7) Disease Associated Microglia Is Identified As A Major Contributor To Neuroinflammation Associated To Chronic Hypoxia Induced-Pulmonary Hypertension
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10:15 AM – 12:15 PM
(957.8) Upregulation of endothelial hypoxia-inducible factor-2 alpha in animals with pulmonary hypertension
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10:15 AM – 12:15 PM
(958.1) Age-related changes in the control mechanisms for vasomotion in the microcirculation
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10:15 AM – 12:15 PM
(958.2) New In Vitro Model to Study Multicellular and Flow Control of Blood-Brain Barrier
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10:15 AM – 12:15 PM
(958.3) Mesenteric Artery Reactivity in Young APOE3 and APOE4 Mice
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10:15 AM – 12:15 PM
(958.4) The Effect of Pregnancy Status on Rat Main Uterine Artery and Radial Uterine Artery Structure and Function
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10:15 AM – 12:15 PM
(958.5) A Novel Non-Linear Approach to Characterizing Astrocytic Neurovascular Coupling with Optogenetics and Computational Modeling
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10:15 AM – 12:15 PM
(958.6) Aging Alters Integrin-mediated Vascular Smooth Muscle Function in Soleus Feed Arteries
Favorite
10:15 AM – 12:15 PM
(958.7) Effect of Oral Contraceptive Phase on Mechanisms of Cutaneous Microvascular Function
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10:15 AM – 12:15 PM
(958.8) Impaired Endothelial Function and Enhanced Contractility of Microarterioles from Persons Living with Human Immunodeficiency Virus (HIV+) is Mediated by Inflamed Perivascular Adipose Tissue
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10:15 AM – 12:15 PM
(959.1) Transcriptomic Analysis of Peripheral Artery Disease Patient Derived Myotubes Reveals Broad Gene Expression Changes and Alternative Splicing
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10:15 AM – 12:15 PM
(959.2) Exploring the Combined Effect of High-Fat High-Sugar Diets and Volumetric Muscle Injury on Skeletal Muscle Metabolic and Contractile Function in Mice
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10:15 AM – 12:15 PM
(959.3) Contrasting Effects of Age on Muscle Contractility in Male and Female Rats
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10:15 AM – 12:15 PM
(959.4) Impact of Obesity on Exercise-Induced Skeletal Muscle Exosomes
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10:15 AM – 12:15 PM
(959.5) Divergent Anabolic Deficits and Pro-inflammatory Effectors of Muscle Wasting in Xenograft and Metastatic Tumor Models of Colorectal Cancer
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10:15 AM – 12:15 PM
(959.6) Use of the Lipolysis Inhibitor Acipimox Fails to Modulate Chronic Muscle Protein Synthesis Rates or Attenuate the Loss of Muscle Mass in a Rodent Model of Severe Burns
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10:15 AM – 12:15 PM
(959.7) The Effect of Damaging Electric Muscle Contraction on Mitochondrial Health and Function
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10:15 AM – 12:15 PM
(959.8) The Effect of Leucine and Doxorubicin Treatment on Skeletal Muscle Mitochondrial Function
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10:15 AM – 12:15 PM
(959.9) Anterior Cruciate Ligament Reconstruction Upregulates Vitamin D Activating Pathways within the Quadriceps
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10:15 AM – 12:15 PM
(960.1) Reduced perception of pain via baroreceptor unloading in patients with chronic back pain
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10:15 AM – 12:15 PM
(960.2) Neuronal Nitric Oxide Synthase expression in brain from male spontaneously hypertensive rats. Implication in the control of cardiovascular function
Favorite
10:15 AM – 12:15 PM
(960.3) Infusion of C20 ceramide induces depressive-like behavior, increases microglia but not astrocyte expression
Favorite
10:15 AM – 12:15 PM
(960.4) Diverse Morphology of Sympathetic Neuron Subpopulations in the Stellate Ganglia
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10:15 AM – 12:15 PM
(960.5) Glutamatergic Activity in the Nucleus of the Solitary Tract contributes to the Circadian Regulation of Blood Pressure
Favorite
10:15 AM – 12:15 PM
(960.6) Voltage Stimulation of the Anterior Ethmoidal Nerve in Rats Produces a Cardiorespiratory Response Similar to the Diving Response
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10:15 AM – 12:15 PM
(960.7) Characterization of Electrodes to Record Neural Signals in the Periphery
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10:15 AM – 12:15 PM
(960.8) Spontaneous Cardiovagal Baroreflex Sensitivity in Females with Multiple Sclerosis
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10:15 AM – 12:15 PM
(960.9) Analysis of Cortical Hemodynamic Responses in the Prefrontal Lobe during Chopsticks Usage
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10:15 AM – 12:15 PM
(961.1) A 24-Hour Fast Increases Liver Cytotoxic T Cell Populations in Genetically Obese Mice: A Preliminary Study
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10:15 AM – 12:15 PM
(961.2) Perinatal supplementation of egg yolk plus docosahexaenoic acid alters the functional organization of the brain in offspring
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10:15 AM – 12:15 PM
(961.3) Novel Energy Drink Improves Cognitive Function and Gaming Performance in Young Adult Gamers: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
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10:15 AM – 12:15 PM
(961.4) Safety Profile of Short-Term Creatine Nitrate and Caffeine Co-Ingested in Resistance Trained Participants
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10:15 AM – 12:15 PM
(961.5) Effects of Creatine Nitrate and Caffeine Alone and Co-ingested on Anaerobic and Muscular Endurance Performance
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10:15 AM – 12:15 PM
(961.6) Inhibition of vitamin C transport impairs neuronal differentiation of hiPSCs
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10:15 AM – 12:15 PM
(961.7) A Bifidogenic Prebiotic Supplement Beneficially Alters Gut Microbial Composition, Activity, and Plasma Metabolites in Healthy Individuals Consuming Low Fiber Diets
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10:15 AM – 12:15 PM
(961.8) Effects of Individual Circulating FFAs on Plasma Oxylipin Levels: Implications for FFA Epoxide-diol Ratios as Indices of Soluble Epoxide Hydrolase Activity
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10:15 AM – 12:15 PM
(961.9) Development of a Dietary and Life-style algorithm for Prophylactic-Remission of IBS: A Case Study
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10:15 AM – 12:15 PM
(962.1) Contribution of the Microbiome to Western Diet-Induced Gene Expression Changes in the Intestine and Vasculature
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10:15 AM – 12:15 PM
(962.2) Investigation of Effects of Hyperglycaemia on the Lung Microbiome in Diabetic Mice
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10:15 AM – 12:15 PM
(963.1) Localization and Functional Characterization of the Cannabinoid Receptor Type 1 (CB1R) in the Kidney
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10:15 AM – 12:15 PM
(963.2) Social Stress Upregulates Histamine H3 Receptor mRNA in Murine Urinary Bladder Smooth Muscle
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10:15 AM – 12:15 PM
(963.3) Increase in Salt Concentration in the Culture Media Enhances Protein Expression of Tumor Necrosis Factor-Alpha Receptor Type 1 in Cultured Renal Cortical Collecting Duct Cells But Not in Proximal Tubular Cells
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10:15 AM – 12:15 PM
(963.4) Myristoylated Protein Kinase C Beta II Inhibitor Attenuates Renal Injury in Mice Subjected to Severe Bilateral Ischemia-Reperfusion
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10:15 AM – 12:15 PM
(963.5) Pharmacological Inhibition of NAPDH Oxidase NOX2 Improves Bladder Dysfunction in Murine Cyclophosphamide-Induced Cystitis
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10:15 AM – 12:15 PM
(963.6) Compound 48/80 increases bladder wall compliance independent of mast cells.
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10:15 AM – 12:15 PM
(963.7) The Influence of Acute High Dose MitoQ on Urinary Kidney Injury Markers in Healthy Adults
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10:15 AM – 12:15 PM
(963.8) The Renin-Angiotensin System after Pig Kidney Transplantation in Baboons
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10:15 AM – 12:15 PM
(963.9) Primary cilia control kidney inflammation and scarring in response to obstruction
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10:15 AM – 12:15 PM
(964.1) Neonatal opioid withdrawal syndrome disrupts the ventral swallow pattern generator in germline-GCaMP6F mouse
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10:15 AM – 12:15 PM
(964.2) Neurokinin 1 and 2 Receptors Differently Modulate PEG2- and Citric Acid-Induced Cough and Ventilatory Responses
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10:15 AM – 12:15 PM
(964.3) Effect of prolonged lipopolysaccharide exposure on lung function and health
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10:15 AM – 12:15 PM
(964.4) Drp1-dependent Regulation of RelA/p65 Is Critical for Endothelial Cell Inflammation
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10:15 AM – 12:15 PM
(964.5) Cellular Senescence as Fibrogenic Mechanism in Smoking Lung
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10:15 AM – 12:15 PM
(964.6) A Strategy to Enhance Confidence in Respiratory Chemoreflex Characterization by Modified Rebreathing
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10:15 AM – 12:15 PM
(964.7) Reproducibility of Respiratory Chemoreflex Characterization by Modified Rebreathing
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10:15 AM – 12:15 PM
(964.8) Erythropoietin Produces a Dual Effect on Carotid Body Chemoreception in Male Rats
Favorite
10:15 AM – 12:15 PM
(964.9) Engineering Spinal Interneurons for Repair of the Injured Cervical Spinal Cord
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10:15 AM – 12:15 PM
(965.1) Administration of Estradiol in Young Adulthood in the Male Sprague Dawley Rat to Mimic Female Physiological Levels is Associated with a Reduction in Body Weight, Lean Mass and Testicular Size
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10:15 AM – 12:15 PM
(965.2) Hypertensive Female Mice Are Protected from Impaired Parenchymal Arteriolar TRPV4-Mediated Dilation and Reactive Astrogliosis
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10:15 AM – 12:15 PM
(965.3) The physiology of polar bear mating (Ursus maritimus)
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10:15 AM – 12:15 PM
(965.4) Gender Differences in Perceived Stress and Biological Stress Markers are Associated with Changes in Resting Heart Rate
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10:15 AM – 12:15 PM
(966.1) How Useful Was That Critical Reflection? Technology Enhanced Learning in Physiology Skill Lab
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10:15 AM – 12:15 PM
(966.2) Teaching Coinciding Remote and In Person Systems Physiology Courses: Lessons Learned
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10:15 AM – 12:15 PM
(967.1) Role of Cardiosphere-Derived Cell Extracellular Vesicles (CDC-EVs) in Modulating CCR2 Mediated Pro-inflammatory Signaling following Cardiac Injury
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10:15 AM – 12:15 PM
(967.2) Seizure Susceptibility Increases After Early-Life Seizures in Zebrafish
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10:15 AM – 12:15 PM
(967.3) Detecting Alterations in Fractal Fibrin Patterns using Light Microscopy
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10:15 AM – 12:15 PM
(968.1) Early life stress drives sustained reductions in circulating butyrate and propionate short-chain fatty acids in pre-pubertal and adult mice
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10:15 AM – 12:15 PM
(968.2) Fluid Balance is Unlikely Modified by the Menstrual Cycle when Ad Libitum Drinking is Permitted During Physical Work in the Heat
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10:15 AM – 12:15 PM
(968.3) Endothelial cell-specific inducible G2APOL1 risk variant induces hypertension and hypertensive kidney disease in uni-nephrectomy and high-salt mice model
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10:15 AM – 12:15 PM
(968.4) Progesterone prolongs time to delivery and attenuates blood pressure possibly by improving inflammation and endothelial function in response to preeclampsia
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10:15 AM – 12:15 PM
(968.5) Bile Duct Ligation Differently Effects Plasma Osmolality but not Blood Pressure in Male vs Female Rats
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10:15 AM – 12:15 PM
(968.6) Dynamic Compartmentalisation of Intracellular Sodium in Collecting Duct Cells
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10:15 AM – 12:15 PM
(968.7) Chronic Circadian Disruption Contributes to Excess Aldosterone Production and Loss of Diurnal Electrolyte Excretion
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10:15 AM – 12:15 PM
(968.8) Endothelin-1 receptor antagonists reduce HbA1c in obese patients with pulmonary hypertension
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10:15 AM – 12:15 PM
(775.10) A cadaveric study on the origins of the uterine artery
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10:15 AM – 12:15 PM
(775.11) Biomechanical consequences of alveolar cleft defect
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10:15 AM – 12:15 PM
(775.12) Localization of The Infraorbital Foramen with Reference to Facial Bony Landmarks: The Predictive Method And Its Accuracy
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10:15 AM – 12:15 PM
(782.10) Surgical Implications in Multiple Variants in the Axillary Artery
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10:15 AM – 12:15 PM
(782.11) Massage application to increase the spread of local anesthesia in sciatic nerve blocks: A cadaveric study
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10:15 AM – 12:15 PM
(782.12) Effect of Alternative Therapeutic Exercise on the Older Adults – A Pilot Study
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10:15 AM – 12:15 PM
(782.13) Rare Forearm Muscle Variations Seen in Two Cadaveric Dissections
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10:15 AM – 12:15 PM
(782.14) Mapping the Saphenous Nerve from Surgical Landmarks: An Anatomic Guide for Adductor Canal Blocks
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10:15 AM – 12:15 PM
(782.15) The Pronator Quadratus Muscle – its Morphology and Functions
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10:15 AM – 12:15 PM
(782.16) Anatomical Variations of the Lumbrical Muscles of the Hand, Regarding Origin, Insertion, Innervation and its Clinical Significance: A Cadaveric Study
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10:15 AM – 12:15 PM
(783.10) Vitamin K2 (MK-7) modulated Nrf2/NLRP3/caspase-1 axis to protect against age-related structural and cognitive deterioration in naturally aged rats
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10:15 AM – 12:15 PM
(783.11) Cadaveric Study of Anatomical Variations in the Limbic System
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10:15 AM – 12:15 PM
(783.12) Evaluating the Association of Sleep & Physical activity with Prolonged Concussion Symptoms
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10:15 AM – 12:15 PM
(783.13) The Gut-Brain Connection: The Inflammatory Role of IL-6 Caused by a Western Diet Authors: Alexis Sotelo1, Barbara Kania1, Darren Ty1, Jonathan J. Wisco, Ph.D.1
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10:15 AM – 12:15 PM
(783.14) Cervical Spinal Cord Injury Induces Distinct Changes in Gut Microbiome Composition Over Time in Rats
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10:15 AM – 12:15 PM
(783.15) The Effect of Atrazine on Fear Behaviors in Rats lt;/p"gt;
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10:15 AM – 12:15 PM
(849.10) Smooth Muscle TRPV4 Channels Signaling Nanodomains in Blood Pressure Regulation
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10:15 AM – 12:15 PM
(849.11) Endothelial signalling operates on a small-world network to control vascular function
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10:15 AM – 12:15 PM
(849.12) Kininase I Inhibition Prevents Angiotensin II-Induced Hypertension and Target Organ Damage
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10:15 AM – 12:15 PM
(849.13) Enriched Housing Rehabilitation for Stroke Recovery in Spontaneously Hypertensive Rats
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10:15 AM – 12:15 PM
(849.14) Age- and sex-specific differences in activation of the cardiac adrenergic cascade
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10:15 AM – 12:15 PM
(849.15) Faster skin wound healing predicts survival after myocardial infarction
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10:15 AM – 12:15 PM
(849.16) Exercise Training Shifts Dependency from NADPH Oxidase 2 to NADPH Oxidase 4 in Endothelium-Dependent Dilation in Coronary Arterioles Distal to Chronic Occlusion
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10:15 AM – 12:15 PM
(849.17) Rho-related BTB Domain-containing Protein 1 Reverses Established Arterial Stiffness in Angiotensin II-treated Mice
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10:15 AM – 12:15 PM
(849.18) Soluble Protein Oligomers Induce Endoplasmic Reticulum Stress and Exacerbated Vasodilation via Nitric Oxide Release in Resistance Arteries from Male and Female Mice
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10:15 AM – 12:15 PM
(849.19) Prior Angiotensin Converting Enzyme Inhibition Differentially Alters Angiotensin II-Induced Oxidative Stress in Male and Female Hypertensive Rats
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10:15 AM – 12:15 PM
(849.20) Impact of the Birth Transition on Striated Muscle Function in Normal Development
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10:15 AM – 12:15 PM
(849.21) Activating P2Y1 receptors improves function in arteries with repressed autophagy
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10:15 AM – 12:15 PM
(849.22) Long-term neuroprosthetic hemotherapy treats autonomic dysreflexia after spinal cord injury
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10:15 AM – 12:15 PM
(849.23) Evidence of Sex Differences in the Endothelin Pathway in Diabetes
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10:15 AM – 12:15 PM
(849.24) Sex Differences in Hydrogen Peroxide-Induced K+ Channel Activation in Arterioles of Ischemic Myocardium after Exercise Training
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10:15 AM – 12:15 PM
(849.25) Aging results in endothelial cell telomere uncapping that induces senescence and physiological dysfunction
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10:15 AM – 12:15 PM
(849.26) CSN5-mediated nuclear exclusion of p27 in vascular smooth muscle cells contributes to the exacerbation of neointimal hyperplasia by CSN8 hypomorphism
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10:15 AM – 12:15 PM
(849.27) Ser14-Rpn6/PSMD11 Phosphorylation Mediates the Activation of 26S Proteasomes by cAMP and Protects against Cardiac Proteotoxic Stress in Mice
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10:15 AM – 12:15 PM
(849.28) Endothelial Pannexin1-purinergic signaling pulmonary hypertension
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10:15 AM – 12:15 PM
(849.29) Mechanisms Determining VO2peak During Single Leg Knee-Extension Exercise in Heart Failure with Preserved Ejection Fraction Patients: Peripheral vs. Central Phenotypes
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10:15 AM – 12:15 PM
(849.30) Neddylation is critical for cardiomyocyte maturation by promoting perinatal metabolic transition
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10:15 AM – 12:15 PM
(849.31) Endothelial Pannexin 3 – B Cell Lymphoma-6 Interactions Protect Against Oxidative Stress
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10:15 AM – 12:15 PM
(849.32) Myoendothelial junction heterogeneity enables phosphatidylserine regulation of Kir2.1-mediated vasodilation
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10:15 AM – 12:15 PM
(849.33) Mechanism of Blood-Heart-Barrier Leakage: Implications for COVID-19 induced Cardiovascular Injury
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10:15 AM – 12:15 PM
(849.34) Endothelial Cell Sprouting in Coronary Collateral Growth
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10:15 AM – 12:15 PM
(849.35) OTUB1: A Key Player in the Adaptive Cardiac Hypertrophy
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10:15 AM – 12:15 PM
(849.36) Dietary Blueberries Improve Vascular Inflammation and Alter the Composition of the Gut Microbiome in Aged Mice
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10:15 AM – 12:15 PM
(849.37) Ablation of Endothelial mTOR is Benign in Young Mice and Reverses Age-Related Arterial and Metabolic Impairments in Old Mice
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10:15 AM – 12:15 PM
(849.38) PDZ-Binding Kinase Drives Pulmonary Artery Smooth Muscle Proliferation and Vascular Remodeling in Pulmonary Arterial Hypertension
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10:15 AM – 12:15 PM
(849.39) Aging and G Protein-Coupled Estrogen Receptor Exacerbates Carotid Artery Structural Remodeling
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10:15 AM – 12:15 PM
(850.10) Exercise training improves cerebral endothelial function in juvenile and mature Ossabaw miniature-pigs
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10:15 AM – 12:15 PM
(850.11) Histone H3K27 Demethylase KDM6A Regulates Cardiac Aging via Induction of HoxC4 mediated ER Stress
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10:15 AM – 12:15 PM
(850.12) Consumption of a High-fiber Diet Improves Systolic Blood Pressure and Vascular Endothelial Function and May Reduce Oxidative Stress in Middle-aged to Older Adults
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10:15 AM – 12:15 PM
(850.13) Early-Life Thymectomy Results in T-Cell Aging and Arterial Dysfunction in Middle-Aged Mice
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10:15 AM – 12:15 PM
(850.14) Maternal Hypertension and Offspring Cardiometabolic Disease Risk is Attenuated after Weight Loss in Obese Preeclamptic-like BPH/5 Female Mice
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10:15 AM – 12:15 PM
(851.10) Arrested Neutrophils in Capillaries is a Novel Mechanism of Myocardial Hypoperfusion in Heart Failure with Preserved Ejection Fraction
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10:15 AM – 12:15 PM
(851.11) Is HFpEF Caused by Coronary Microvascular Disease?
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10:15 AM – 12:15 PM
(852.10) Contribution of ASICs to Cardiac Remodeling and Dysautonomia Associated with Heart Failure
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10:15 AM – 12:15 PM
(852.11) Characterization of the spontaneous right ventricular hypertrophy and evolution to heart failure in Wistar Kyoto rat strain
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10:15 AM – 12:15 PM
(852.12) Renal inflammatory signaling alters cardiomyocyte kinetics and lead to HFpEF in CKD: A mechanistic proof of concept study
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10:15 AM – 12:15 PM
(852.13) Role of inflammation and ER stress in HFpEF pathogenesis
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10:15 AM – 12:15 PM
(852.14) Differences in Immune Cell Mitochondrial Function in Black and White Patients with Heart Failure with Preserved Ejection Fraction
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10:15 AM – 12:15 PM
(852.15) Cardiac AMPK is not required for cardioprotection by metformin in pulmonary hypertension induced right heart failure
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10:15 AM – 12:15 PM
(852.16) A novel and important role of UFM1-binding protein 1 (UFBP1) in the regulation of ER and cardiac homeostasis
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10:15 AM – 12:15 PM
(852.17) Delivery of TAPI-1 via Neutrophil Membrane Fusogenic Liposomal Nanoparticles Can Effectively Ameliorate Cardiac Dysfunction in Heart Failure
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10:15 AM – 12:15 PM
(852.18) Elimination of AKT in Cardiomyocytes Causes Complex Reorganization of Signal Transduction leading to AMPK Inhibition and Fatal Cardiac Atrophy
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10:15 AM – 12:15 PM
(852.19) Using Model-Based Analysis and Physiology-Informed Machine Learning to Refine the Stratification of Phenotypes in Heart Failure
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10:15 AM – 12:15 PM
(853.10) Postinjury Inhibition of Endothelin-1 Dependent Renal Vasoregulation Mitigates Rhabdomyolysis-Induced Acute Kidney Injury
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10:15 AM – 12:15 PM
(853.11) The Role of Tamm-Horsfall Protein in the Pathogenesis of Crystalline Nephropathy
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10:15 AM – 12:15 PM
(853.12) Different Murine Models of Kidney Injury Reveal a Common Pattern of Dysregulation within the Polyamine System in Favour of its Catabolic Pathways
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10:15 AM – 12:15 PM
(853.13) The Molecular Chaperone, GRP170, Protects Against Acute Kidney Injury and ER Stress in Mice
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10:15 AM – 12:15 PM
(853.14) Angiotensin AT2 Receptor Activation during Ischemic Injury Protects against High Salt-Induced Hypertension and Proteinuria in the Long-term: Role of IL-17A Cells
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10:15 AM – 12:15 PM
(853.15) Fatty acid amide hydrolase (FAAH) inhibition mitigates TGF-β1-induced fibrogenesis via the anandamide-COX-2-dependent pathway
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10:15 AM – 12:15 PM
(853.16) Serial Intravital 2-photon Imaging Deciphers in Vivo Renal Myofibroblast Dynamics at the Fork of Acute Kidney Injury-induced Tubular Repair and Nephron Loss
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10:15 AM – 12:15 PM
(853.17) Myostatin Deletion Protects Against Renal Dysfunction During a High Salt Diet
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10:15 AM – 12:15 PM
(853.18) Inhibition of Na-H exchanger 3 ameliorates lower limb ischemia/reperfusion-induced acute kidney injury through preservation of mitochondrial biogenesis in mice
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10:15 AM – 12:15 PM
(853.19) Effects of flow and polycystin-1 dysfunction on ATP release in the inner medullary collecting duct of the kidney
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10:15 AM – 12:15 PM
(856.10) Renal-derived human sPRR increases blood pressure in female but not male mice
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10:15 AM – 12:15 PM
(856.11) Renal TLR7 expression is associated with renal injury in female mouse model of systemic lupus erythematosus
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10:15 AM – 12:15 PM
(856.12) Exploring Sex Differences in Renal Sodium Transporters with Four Core Genotype (FCG) Model
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10:15 AM – 12:15 PM
(856.13) Angiotensin Ii-induced Hypertension and Glomerular and Tubulointerstitial Injury in Mutant Mice With Kidney Proximal Tubule-selective Deletion of Mitochondrial Nad+-dependent Deacetylase Sirtuin 3: Focus on Sex Differences
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10:15 AM – 12:15 PM
(856.14) Sexual dimorphisms in renal mitochondrial bioenergetics
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10:15 AM – 12:15 PM
(856.15) Modulation of Estrogen Receptor Signaling Sensitizes Female Mice to the Development of Diabetes
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10:15 AM – 12:15 PM
(856.16) G Protein-coupled Estrogen Receptor 1 and Pregnancy Confer Protection against Renal Injury in Aged Female Mice
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10:15 AM – 12:15 PM
(858.10) Young Healthy Men and Women Have Similar Arterial Stiffness at Rest and Post-Acute Inflammation
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10:15 AM – 12:15 PM
(858.11) Hypogonadal Hypertension In Male Sprague-Dawley Rats Is Reversed By Testosterone and its Genomically Inactive Metabolite 5β-Dihydrotestosterone
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10:15 AM – 12:15 PM
(858.12) Sexually dimorphic role of smooth muscle cell estrogen receptor alpha in aging-associated arterial stiffness
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10:15 AM – 12:15 PM
(865.10) Changes in Oral Microbial Diversity in a Piglet Model of Traumatic Brain Injury
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10:15 AM – 12:15 PM
(865.11) Characterizing the Capacity of Acinetobacter calcoaceticus to Grow in Intestinal Conditions and Modulate the Gut Epithelium
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10:15 AM – 12:15 PM
(875.10) Caffeine Induces Spontaneous Ventricular Tachyarrhythmias and Bidirectional Ventricular Tachycardia: Increased Vulnerability with Aging
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10:15 AM – 12:15 PM
(875.11) Estrogen Receptor-a in the Subfornical Organ Controls Glucose Homeostasis During Obesity in Males
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10:15 AM – 12:15 PM
(875.12) Characterizing the Effects of High Fat and High Carbohydrate Diets on Feeding Behavior and Energy Expenditure in Mice
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10:15 AM – 12:15 PM
(875.13) Artificial Synchronization of Sex Steroid Hormones Normalizes Kisspeptin Expression and Placentation in the Preeclamptic-Like BPH/5 Mouse
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10:15 AM – 12:15 PM
(875.14) Kisspeptin and Sex Steroid Hormone Receptors Are Upregulated at the Maternal-Fetal Interface of the Preeclamptic-like BPH/5 Mouse
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10:15 AM – 12:15 PM
(875.15) Myeloid Sulf Deletion and Immune Dysfunction in Multiple Sulfatase Deficiency
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10:15 AM – 12:15 PM
(875.16) Polycystin 1 ciliary localization is regulated by its aGPCR activity.
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10:15 AM – 12:15 PM
(875.17) Select Amino Acid Formulation Influenced Anion Secretion Induced by Th2 Cytokines in Human Bronchial Epithelial Cells (HBECs)
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10:15 AM – 12:15 PM
(875.18) Select Amino Acids Increase Anion Secretion in Human Bronchial Epithelial Cells (HBEC) with F508del and Nonsense Mutations: Alternative Approach to Restoring Airway Anion Secretion in Cystic Fibrosis
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10:15 AM – 12:15 PM
(881.10) Role of TFE3 in Mitochondrial Adaptations to Skeletal Muscle Disuse
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10:15 AM – 12:15 PM
(881.11) Mitochondria from Skeletal Muscle Cells Derived from Old Donors Show Reduced Energy Production and Respiratory Capacity
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10:15 AM – 12:15 PM
(885.10) Acute Heat Exposure Improves Microvascular Function in Skeletal Muscle of Aged Humans
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10:15 AM – 12:15 PM
(885.11) A NIRS-derived Skeletal Muscle Oxygen Consumption Method Accurately Reflects the Gold Standard Direct Fick Method during Single-leg Knee Extension Exercise
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10:15 AM – 12:15 PM
(886.10) Myonuclei Can Replicate DNA
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10:15 AM – 12:15 PM
(886.11) The Metabolomic Pathways of the Senescence-Associated Secretory Phenotype in C2C12 Myoblasts
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10:15 AM – 12:15 PM
(886.12) Agreement Between MRI, Ultrasound, and Histology in Detecting Size Changes of the Vastus Lateralis Following Resistance Training
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10:15 AM – 12:15 PM
(886.13) Extracellular Matrix Content and Remodeling Does Not Differ Between Higher-Responders and Lower-Responders to Resistance Training
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10:15 AM – 12:15 PM
(886.14) Skeletal Muscle LINE-1 Gene Regulation and Inflammatory Response to Chronic, Voluntary Endurance Training in Rodents
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10:15 AM – 12:15 PM
(886.15) Altered Activation of Inflammatory Signaling with Diet-induced Insulin Resistance in the Dystrophic Diaphragm
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10:15 AM – 12:15 PM
(886.16) Cumulative effects of H+ and Pi on peak power of skeletal muscle fibers from young and older adults
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10:15 AM – 12:15 PM
(886.17) Global DNA Methylation Status in Relation to Resistance Training with High vs Low Loads to Failure
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10:15 AM – 12:15 PM
(886.18) Effects of different types of resistance exercise failure training on the methylation status of genes that drive skeletal muscle hypertrophy
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10:15 AM – 12:15 PM
(886.19) Enhanced Senescent Cell Burden in the Quadriceps, Articular Cartilage and Periarticular Bone Accompanies Atrophy and Osteoarthritis Following ACL Injury in Mice
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10:15 AM – 12:15 PM
(886.20) Gene Expression in Response to High Frequency, Low Magnitude Loading on the Anterior Cruciate Ligament
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10:15 AM – 12:15 PM
(888.10) Severe Diaphragm Fiber Weakness And Normal Response To Intraoperative Phrenic Stimulation In An ECMO-Dependent Adult Receiving Lung Transplant
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10:15 AM – 12:15 PM
(888.11) Cardiorespiratory and Metabolic Kinetics During Recovery After an Incremental Test in Young Physically Active Smokers
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10:15 AM – 12:15 PM
(888.12) Dapagliflozin Attenuates Sympathetic and Pressor Responses to Stress in Young Prehypertensive Spontaneously Hypertensive Rats
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10:15 AM – 12:15 PM
(888.13) Limb Hemodynamic Responses to a Single Bout of Inspiratory Muscle Strength Training
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10:15 AM – 12:15 PM
(888.14) High Sodium Intake Differentially Impacts Brachial Artery Flow Mediated Dilation When Evaluated with Reactive Versus Active Hyperemia
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10:15 AM – 12:15 PM
(888.15) Blood Pressure and Arterial Stiffness after a Maximal Aerobic Exercise in Young Adult Binge Drinkers and Moderate Drinkers
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10:15 AM – 12:15 PM
(888.16) Central hemodynamic response during submaximal and exhaustive exercise in humans with high affinity hemoglobin and compensatory polycythemia
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10:15 AM – 12:15 PM
(888.17) The Effects of Exercise on the Sport Concussion Assessment Tool 3 (SCAT3)
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10:15 AM – 12:15 PM
(888.18) Cerebrovascular Dynamics During Light Exercise
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10:15 AM – 12:15 PM
(888.19) Individuals with a Previous Symptomatic COVID-19 Infection Have Altered Blood Pressure and Heart Rate Variability During Acute Exercise
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10:15 AM – 12:15 PM
(888.20) Associations Between Heart Rate and Skeletal Muscle Oxygen Saturation (SmO₂) in Upper and Lower Extremities During Self-Paced Walking
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10:15 AM – 12:15 PM
(888.21) Do Adolescents With Insulin Resistance Demonstrate Impaired Heart Rate Recovery From Exercise?
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10:15 AM – 12:15 PM
(888.22) Rapid Onset Vasodilation: Impact of Cardiorespiratory Fitness
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10:15 AM – 12:15 PM
(898.10) Basal and Hypoxic Respiratory Behaviors in Aged 6-OHDA-Induced SN Lesion PD Rat Model: Effects of the 5-HT1A Receptor Agonist Buspirone
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10:15 AM – 12:15 PM
(898.11) Neuromuscular Pathology of Extrinsic Tongue Muscles in the Pink1-/- Rat Model of Parkinson Disease
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10:15 AM – 12:15 PM
(898.12) Upper Airway Dysfunction and Discoordination are Reversed by Isometric Tongue Exercise in a Novel Rodent Model of Hypoglossal Motor Neuron Loss
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10:15 AM – 12:15 PM
(898.13) Accessory Muscle Support of Breathing in Young Dystrophin-deficient mdx Mice
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10:15 AM – 12:15 PM
(898.14) Chemogenetic Activation of Hypoglossal Motoneurons in Neuromuscular Disease
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10:15 AM – 12:15 PM
(898.15) Prolonged diaphragm activation using closed loop optogenetic stimulation
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10:15 AM – 12:15 PM
(898.16) Hypoglossal Motoneuron (XII MN) Survival Over the Lifespan in Pompe Disease
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10:15 AM – 12:15 PM
(898.17) The Pattern of Ampakine and Hypoxia Exposure Determines Phrenic Motor Facilitation
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10:15 AM – 12:15 PM
(901.10) Aging Selectively Reduces Mitochondrial Volume Density and Respiratory Capacity in Type IIx/IIb Diaphragm Muscle Fibers
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10:15 AM – 12:15 PM
(901.11) Effect of Aquatic Exercise Training on Left Ventricular Afterload in in Middle-aged and Older Normotensives: Evaluation by Polar coordinate description
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10:15 AM – 12:15 PM
(901.12) Spontaneous Intrinsic Hepatic Vascular Oscillations
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10:15 AM – 12:15 PM
(924.10) Expression profile of miR-148a and miR-155 associated with apoptosis mechanism in pancreatic cancer
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10:15 AM – 12:15 PM
(924.11) The role of physical exercise in apoptosis in an experimental cerebral ischemia model
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10:15 AM – 12:15 PM
(924.12) Improving the Percutaneous Approach for the Management of Trigeminal Neuralgia
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10:15 AM – 12:15 PM
(924.13) Evaluation of Obturator Nerve Fascicular Topography Using Landmark Morphometrics - a Pilot Study
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10:15 AM – 12:15 PM
(924.14) The impact of hydro-dissection method in fascial plane delineation of dorsum of human hand
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10:15 AM – 12:15 PM
(925.10) Using Donor and Family Statements to Promote Humanism in the Anatomy Lab
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10:15 AM – 12:15 PM
(925.11) Missing Anatomy Background: Microlearning Can Help
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10:15 AM – 12:15 PM
(925.12) Student Use and Response to In-House Cadaveric Dissection Videos
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10:15 AM – 12:15 PM
(925.13) Impact of team-based virtual microscopy on student learning in histology
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10:15 AM – 12:15 PM
(925.14) Anatomy Education-Paradigm Shift from Passive to Active Learning-Effects on Student Engagement, Comprehension and Retention A Review of Literature from 2012 to 2022
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10:15 AM – 12:15 PM
(925.15) Exploring Virtual Reality (VR) as an Anatomy Teaching Supplement
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10:15 AM – 12:15 PM
(925.16) Assessment of Virtual 3D Anatomy and Prosected Cadaver Use for Anatomy Laboratory Sessions Through Regional Dissection
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10:15 AM – 12:15 PM
(925.17) Does the Use of Pre-made Digital Flashcards Aid in Medical Students Learning of Anatomy
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10:15 AM – 12:15 PM
(925.18) Case Study: Superficial Ulnar Artery and its Clinical Significance
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10:15 AM – 12:15 PM
(925.19) Amalgamation of Arts, Anatomy and Passion in Creating an Anatomy Atlas for Active Learning
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10:15 AM – 12:15 PM
(925.20) Scroll Away! Understanding the Utility of Multi-Planar Anatomical Images in Instructional Cases for Medical Students
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10:15 AM – 12:15 PM
(925.21) Anatomy-Focused Exercise Videos to Combine Studying with Wellness
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10:15 AM – 12:15 PM
(947.10) GAL3 Excretion Regulates Smooth Muscle Cell Survival and Proliferation
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10:15 AM – 12:15 PM
(947.11) Targeted Nanoparticles to Mitigate Radiation-Induced Blood-Brain Barrier Disruption and Cognitive Impairment
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10:15 AM – 12:15 PM
(947.12) High Intensity Exercise Improves Cardiorespiratory Capacity in a Mouse Model of Hypertrophic Cardiomyopathy
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10:15 AM – 12:15 PM
(947.13) Effect of Acute Isometric Handgrip Exercise on Vascular Function in Children with Congenital Heart Disease
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10:15 AM – 12:15 PM
(947.14) Biophysical Properties of Endothelial Mechanotransduction Mediated by Glycocalyx
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10:15 AM – 12:15 PM
(947.15) Heart rate variability during different phases of menstrual cycle
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10:15 AM – 12:15 PM
(947.16) Adipose tissue expression of HuR modulates cardiac pathology via adipose tissue-derived extracellular vesicles
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10:15 AM – 12:15 PM
(947.17) Influence of Cognitive Challenges During Exercise on Post-Exercise Cerebrovascular Function
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10:15 AM – 12:15 PM
(947.18) Neuronal Nitric Oxide Synthase and Neural growth factor interaction in the development of ventricular hypertrophy toward heart failure in the spontaneously hypertensive rats
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10:15 AM – 12:15 PM
(947.19) The Antiarrhythmic Effect of Inhibition of the Mitochondrial Calcium Uniporter under Catecholamine Overload is Partly Dependent on Mitochondrial Function Preservation
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10:15 AM – 12:15 PM
(947.20) Promoting Mitochondrial Biogenesis Protects against Doxorubicin-Induced Cardiomyocyte Injury
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10:15 AM – 12:15 PM
(947.21) Development of a Specific 5-HT7 Receptor Antibody: Is This Even Possible?
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10:15 AM – 12:15 PM
(947.22) More evident roles of nNOS for the regulation of Ca2+-sensitivity and SERCA activity in the right than the left ventricular cardiomyocytes of rats
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10:15 AM – 12:15 PM
(947.23) The role of IR-induced swelling in OPA1-MICOS interaction in cardiac mitochondria
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10:15 AM – 12:15 PM
(947.24) The effects of dietary nitrate supplementation in post-menopausal women: Does timing matter?
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10:15 AM – 12:15 PM
(947.25) Reduced Vasoreactivity in Older Compared to Young Adults Following Handgrip Exercise and Cold Pressor Test
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10:15 AM – 12:15 PM
(947.26) Free Day, but Not Work Day, Sleep Duration Is Inversely Associated With Aortic Stiffness in Apparently Healthy Young Adults
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10:15 AM – 12:15 PM
(947.27) Nighttime Blood Pressure Dipping is Attenuated in Young and Apparently Healthy Black Adults Compared to White Adults
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10:15 AM – 12:15 PM
(947.28) Electronic Cigarette Exposure Induces Vascular Endothelial Dysfunction with NADPH Oxidase Activation and eNOS Uncoupling
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10:15 AM – 12:15 PM
(947.29) Chronic Unpredictable Stress Impairs the Reactivity of the Pudendal Artery and Corpus Cavernosum in Male Mice
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10:15 AM – 12:15 PM
(947.30) High-Frequency 4D Ultrasound Evaluation of Temporal Changes in Endocardial Surface Strain after Myocardial Infarction
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10:15 AM – 12:15 PM
(947.31) The Impact of Muscular Strength On Cardiovascular Disease Risk Factors
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10:15 AM – 12:15 PM
(947.32) Loss of eNOS in Endothelial Cells Promotes Proliferation
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10:15 AM – 12:15 PM
(947.33) Latent Mixture Modeling to Identify Homogeneous Subgroups Predictive of Cerebrovascular Reactivity
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10:15 AM – 12:15 PM
(948.10) Exploring the role of redundant RFamide neuropeptide pathways during sleep in Caenorhabditis elegans
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10:15 AM – 12:15 PM
(948.11) Nitric Oxide Inhibits TRPV4-mediated Hemichannel Opening in Porcine Nonpigmented Ciliary Epithelium
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10:15 AM – 12:15 PM
(948.12) Silencing of NILCO by Small Interfering RNA Effects MDR1 in Colon Cancer Cells
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10:15 AM – 12:15 PM
(948.13) A Stressful Question - How Does 3 5 cyclic adenosine monophosphate Signaling Affect Oxygen Metabolism Within Malignant Hyperthermia Susceptible (MHS) B-lymphocytes?
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10:15 AM – 12:15 PM
(948.14) Evidence for a Highly Cytokine-Sensitive Network of Iron-Associated Genes in Islets
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10:15 AM – 12:15 PM
(948.15) Syncytialization of BeWo trophoblasts induces changes in angiogenic signaling and response to hypoxia
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10:15 AM – 12:15 PM
(948.16) Time Course of Fat Accumulation in Various Organs of Young OLETF Rats
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10:15 AM – 12:15 PM
(948.17) Measuring AMPK Activity in Vivo Using a Genetically-Encoded Biosensor
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10:15 AM – 12:15 PM
(948.18) Distribution and Allelic Frequency of the Enamelin Gene Variant rs7671281 Associated to Amelogenesis Imperfecta and High-risk Caries in Puerto Rico
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10:15 AM – 12:15 PM
(948.19) Role of HCN Currents in Epileptiform Activity in Subicular Neurons
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10:15 AM – 12:15 PM
(953.10) Sex Differences in the Severe- and Extreme-Intensity Power-Duration Relationships
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10:15 AM – 12:15 PM
(953.11) Identifying Critical DO2 with Compensatory Reserve during Simulated Hemorrhage in Humans
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10:15 AM – 12:15 PM
(953.12) Hydration, Ad Libitum Consumption, and Performance are Similar Between a Milk Permeate Solution, a Traditional Sports Drink, and Water Following Overnight Fluid Restriction in Recreationally Active Adults
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10:15 AM – 12:15 PM
(953.13) Acute wheel-running increases markers of stress and aversion-related signaling in the basolateral amygdala of male rats
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10:15 AM – 12:15 PM
(953.14) The Influence of Self-Reported and Actigraphy-Derived Sleep Quality on Cardiometabolic Health in a Diverse Cohort of Healthy Adults
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10:15 AM – 12:15 PM
(953.15) The Relationship Between Central and Peripheral Chemoreflex Sensitivities and V̇E-V̇CO2 Slope Below and Above the Respiratory Compensation Point of Incremental Exercise
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10:15 AM – 12:15 PM
(953.16) Tattoos Effect Local Sweat Excretion Rate of Epidermal Growth Factor During Outdoor Group Fitness Exercise
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10:15 AM – 12:15 PM
(953.17) Moderate hypoxia decreases selective attention performance as assessed via a domain-specific gamified assessment
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10:15 AM – 12:15 PM
(953.18) The Impact of Removal of Exercise for 3 Days on Glycemic Control in Older Active Adults
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10:15 AM – 12:15 PM
(953.19) Objectively Measured Vigorous-Intensity Physical Activity is Related to Endothelial Function in Midlife and Older Men but not in Estrogen-Deficient Postmenopausal Women
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10:15 AM – 12:15 PM
(953.20) Dynamic Cerebral Autoregulation is Intact in Chronic Kidney Disease
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10:15 AM – 12:15 PM
(953.21) Exercise Preconditioning Preserves Cardiac Function and Enhances Cardiac Recovery Following Dobutamine Stimulation in Doxorubicin-Treated Rat Hearts
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10:15 AM – 12:15 PM
(953.22) Sex Differences in the Relationship between Exercise and the Brain
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10:15 AM – 12:15 PM
(953.23) The Influence of Ovariectomy on Performance and Thermoregulation During Exertional Heat Stroke in Mice
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10:15 AM – 12:15 PM
(953.24) A gamified assessment does not identify alterations in cross-domain cognitive performance with acute moderate hypoxia
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10:15 AM – 12:15 PM
(953.25) Is there a relationship between in-season injury risk and Y balance or vertical jump in elite youth soccer players?
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10:15 AM – 12:15 PM
(953.26) A Single Glucocorticoid Injection Accelerate Erythropoiesis but Does Not Improve Performance
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10:15 AM – 12:15 PM
(953.27) Exercise Increases Mitochondrial Biogenesis in Single-Housed Adolescent Female Rats Treated with Cocaine
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10:15 AM – 12:15 PM
(959.10) The Role of Mitophagy in Quadriceps Atrophy after Non-Invasive Anterior Cruciate Ligament Injury
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10:15 AM – 12:15 PM
(959.11) The LP07 and LLC pre-clinical models of lung cancer present divergent anabolic deficits and expression of pro-inflammatory effectors of muscle wasting
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10:15 AM – 12:15 PM
(959.12) Chronic AICAR treatment enhances anabolic signaling in sarcopenic skeletal muscle
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10:15 AM – 12:15 PM
(959.13) Autophagy Impairment and Sarcopenia in Type-Identified Muscle Fibers of Aging Extensor Digitorum Longus Muscle
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10:15 AM – 12:15 PM
(959.14) Assessing High- and Low-intensity Physical Rehabilitation Approaches to Address Skeletal Muscle Dysfunction Following Volumetric Muscle Loss
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10:15 AM – 12:15 PM
(959.15) Positive Association between NIRS-derived measures of Microvascular Reactivity and Mitochondrial Capacity in the Quadriceps and Hamstrings
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10:15 AM – 12:15 PM
(959.16) The Whole-Body and Muscle Specific Metabolic Costs of Repair Following Volumetric Muscle Loss Injury: The Role of Limited Physical Activity and Adjunctive Oxidative Modulation
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10:15 AM – 12:15 PM
(959.17) Oxytocin, Prostaglandin F2α, and Prostaglandin E2 Induced Contractions in Isolated Uterine Smooth Muscle Strips from Non-pregnant, Late Pregnant, and Postpartum Rats
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10:15 AM – 12:15 PM
(959.18) Myofibers sarcolemma mechanical properties are affected by the isolation method
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10:15 AM – 12:15 PM
(961.10) Pharmacokinetics of a 40mg Sublingual Dose of Delta-Tocotrienol Powder
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10:15 AM – 12:15 PM
(961.11) Creatine Nitrate and Caffeine Alone and Co-ingested on Cognition, Readiness to Perform, and Sleep Quality
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10:15 AM – 12:15 PM
(961.12) Pharmacokinetics of a 80mg Sublingual Dose of Delta-Tocotrienol Powder
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10:15 AM – 12:15 PM
(963.10) Augmented Urinary Excretion of Angiotensinogen Precedes Albuminuria in Human Young Adults with Overweight and Mice with High Fat Diet-Induced Type 2 Diabetes.
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10:15 AM – 12:15 PM
(963.11) Loss of Renal Mass Exacerbates Renal Damage in a Mouse Model of High-Renin Hypertension
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10:15 AM – 12:15 PM
(963.12) Increased HDAC1 Expression Increases Mitochondrial Dysfunction in Endothelial Cells
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10:15 AM – 12:15 PM
(964.10) Influence of cotinine on breathing related motor output
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10:15 AM – 12:15 PM
(964.11) Locomotor Training Enhances Respiratory Plasticity in a Pre-clinical Model of Cervical Spinal Cord Injury
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10:15 AM – 12:15 PM
(964.12) Chronic Exposure to Electronic Cigarettes Induces Lung Oxidative Stress, Inflammation, Fibrosis, and Impaired DNA Repair
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10:15 AM – 12:15 PM
(964.13) GAA Deficiency Disrupts Distal Airway Cells in Pompe Disease
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10:15 AM – 12:15 PM
(964.14) Anatomical Basis of Interactions Between Locomotor and Respiratory Systems
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10:15 AM – 12:15 PM
(964.15) Oxygen therapy limiting peripheral oxygen saturation to 89-93% is associated with a better survival prognosis for critically ill COVID-19 patients at high altitudes
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10:15 AM – 12:15 PM
(964.16) Studying Quantitative Relationships Between the Indicators of Physical Development at Birth and the Functional State of the External Respiratory System
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11:45 AM – 12:45 PM
(825.1) Monitoring of vitamin-mineral metabolism’ indicators in cows of different period of lactation
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11:45 AM – 12:45 PM
(825.2) The influence of using plant-mineral bolus in early fresh period on the efficiency of the first inseminations of dairy cows
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11:45 AM – 12:45 PM
(825.3) The influence of vitamin-mineral supplementation with prolonged action on cows and on the calcium and phosphorus metabolism in calves
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11:45 AM – 12:45 PM
(825.4) The influence of vitamin-mineral supplementation with prolonged action on cows and on the protein metabolism in calves
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11:45 AM – 12:45 PM
(825.5) Trichinosis of Marine Mammals in the Territory of Chukotka
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11:45 AM – 12:45 PM
(825.6) The Effect of the Klim Feed Additive on Cortisol Levels in Cows During Stress
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11:45 AM – 12:45 PM
(825.7) State and prospect of application immunocorrection therapy in castration of piglets and 5-month-old boars in pig breeding farm
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11:45 AM – 12:45 PM
(825.8) Results of using probiotic based on Enterococcus Faecium L-3 strain for enteritis of calves
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11:45 AM – 12:45 PM
(825.9) NT-proBNP as a diagnostic marker of dilated cardiomyopathy in dogs
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11:45 AM – 12:45 PM
(826.1) Metabolic trade-off and adipose tissue role in Neonatal Sepsis
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11:45 AM – 12:45 PM
(826.2) A High-Through Put Pro-inflammatory screening of natural products using mouse RAW 264.7 macrophages indicate a more significant number of pro-inflammatory natural herbal products than anti-inflammatory
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11:45 AM – 12:45 PM
(826.3) VEGFR2 signals with VE-cadherin and PECAM to facilitate leukocyte transendothelial migration
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11:45 AM – 12:45 PM
(826.4) Immune-modulating Effects of Low Carbohydrate Ketogenic Foods in Healthy Canines
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11:45 AM – 12:45 PM
(826.5) Role of IL-5/IL-5RA Axis in Eosinophilic Allergic Response in Canines with Dermatological Problems
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11:45 AM – 12:45 PM
(826.6) Altered gut microbiome structure and its association with inflammation markers in patients with Crohn’s disease in comparison to healthy siblings
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11:45 AM – 12:45 PM
(826.7) Thrombo-inflammatory Biomarkers in Patients with End-Stage Renal Disease
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11:45 AM – 12:45 PM
(826.8) C1q/gC1qR-Mediated Activation of Extrinsic Coagulation
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11:45 AM – 12:45 PM
(826.9) Junction adhesion molecule-A is involved in asthma through JNK and ERK pathway
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11:45 AM – 12:45 PM
(827.1) Mechanical Tension-induced Vascular and Alveolar Morphogenesis during Lung Regeneration
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11:45 AM – 12:45 PM
(827.2) Alteration in MUC2 and OCLN Protein Expression in Lung Epithelial Cells After E-Cigarette Chemical Exposure
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11:45 AM – 12:45 PM
(827.3) Dedicator of cytokinesis 2 (DOCK2) mediates chronic high-fat and high-fructose diet induced lung injury
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11:45 AM – 12:45 PM
(827.4) RAGE Signaling and Models of COPD Pathogenesis
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11:45 AM – 12:45 PM
(827.5) Cardiac and pulmonary expression of renin, prorenin, mast cells and macrophages in a rat model of fat embolism syndrome
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11:45 AM – 12:45 PM
(827.6) Endothelial Senescence Mediates Hypoxia-induced Vascular Remodeling in the Lung through TWIST1 Signaling
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11:45 AM – 12:45 PM
(827.8) L-Citrulline Attenuates Effects of Serotonin Signalling During Proliferation of Pulmonary Artery Smooth Muscle Cells in Pulmonary Hypertension
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11:45 AM – 12:45 PM
(827.9) The CHST11-CP-metal ionic axis contributes to NSCLC immune escape and metastasis
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11:45 AM – 12:45 PM
(828.1) Understanding the Tissue-Specific Transcriptional Effects of Mitochondrial Introgression in Drosophila
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11:45 AM – 12:45 PM
(828.2) P-glycoprotein deficiency results in intestinal developmental delay in C. elegans
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11:45 AM – 12:45 PM
(828.3) Embryonic Over-Expression Of RAGE In Mouse Lung Modulates Thyroid Transcription Factor (TTF)-1 And Surfactant Expression
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11:45 AM – 12:45 PM
(828.4) Different human placental epigenetics changes in pregnancies affected with preeclampsia and intrauterine growth restriction
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11:45 AM – 12:45 PM
(828.5) Identification of a direct role of CPSF6 and a key cis-acting motif in promoting TRIM9 proximal polyA site usage
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11:45 AM – 12:45 PM
(828.6) Epigenome-wide association study of bronchopulmonary dysplasia (BPD) in preterm infants: Results from the Discovery-BPD program
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11:45 AM – 12:45 PM
(829.1) HMGB1 is necessary for the Receptors for Advanced Glycation End-products (RAGE) inhibition of DNA Double Strand Breaks in trophoblast cells
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11:45 AM – 12:45 PM
(829.2) Decreased Placental mTOR Signaling And Increased Placental Apoptosis Are Associated With Secondhand Smoke (SHS)-Induced Intrauterine Growth Restriction (IUGR) In Mice
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11:45 AM – 12:45 PM
(829.3) In Vivo Evaluation of Validated Targets from High Throughput Screening Models for Sulfur Mustard Ocular Injury
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11:45 AM – 12:45 PM
(829.4) Hair-Bearing Human Skin Organoids from Pluripotent Stem Cells: A Novel Source of Advanced Skin Substitutes for Wound Repair
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11:45 AM – 12:45 PM
(829.5) The Impact of Early Life Exposure to Glyphosate
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11:45 AM – 12:45 PM
(829.6) Extracellular Vesicles from iPSC derived Muscle Progenitor Cells Rejuvenate the Dysfunctional Muscle Stem Cells during Aging
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11:45 AM – 12:45 PM
(830.1) Leveraging AI Transfer Learning for Rapid and Accurate Identification and Quantification of Cellular Biomarkers in Microscopy Images
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11:45 AM – 12:45 PM
(830.3) Does CADM1 Immunohistochemistry Distinguish Mycosis Fungoides from its Closest Mimickers?
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11:45 AM – 12:45 PM
(938.1) Stimulation of Neutrophils in Whole Blood Enhances the Pro-inflammatory Activity of Neutrophil-Derived Microvesicles
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11:45 AM – 12:45 PM
(939.1) Characterization of Pulmonary Fibroblast Response to Aspergillosis fumigatus Exposure and Clinical Implications on the Development of Invasive Aspergillosis
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11:45 AM – 12:45 PM
(941.1) Salivary Microbiota is Associated with Cannabis Use in Adolescents
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11:45 AM – 12:45 PM
(941.2) Syndecan-4 functionalized elastomeric biomaterial promotes in situ endovascular tissue repair and regeneration
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11:45 AM – 12:45 PM
(941.3) Worms With Armor: Tegumental Adaptations of Stomach Fluke, Dinurus sp. (Trematoda: Hemiuridae)—Ultrastructural Characteristics
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11:45 AM – 12:45 PM
(942.1) A Transcriptional Regulation Bioinformatics Pipeline to Predict Co-Regulated Genes in Vascular Smooth Muscle Cell Phenotypic Transitions During Atherosclerosis
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11:45 AM – 12:45 PM
(942.2) Deep Learning-Based Identification of Microglial Cellular Populations in Glioblastoma Patients
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11:45 AM – 12:45 PM
(825.10) Evaluation of the cellular and extracellular fluid of the body of calves using bio impedancemetry
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11:45 AM – 12:45 PM
(825.11) Evaluation of echocardiography indicators of cows and calves with myocardial dystrophy
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11:45 AM – 12:45 PM
(825.12) Pharmacological evaluation of a complex drug against anthrax and parasitosis of Rangifer tarandus
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11:45 AM – 12:45 PM
(825.13) Experience in the application of remote anesthesia in Callorhinus ursinus
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11:45 AM – 12:45 PM
(825.14) Comparative Assessment of the Content of Immunoglobulins in the Blood Serum of Calves Obtained From Healthy Cows and Cows with Genital Mycoplasmosis
Favorite
11:45 AM – 12:45 PM
(825.15) Blood levels and productivity of lambs according to breed
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11:45 AM – 12:45 PM
(825.16) Study of metabolic processes in cows with hyperbilirubinemia in the postpartum period
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11:45 AM – 12:45 PM
(825.17) Results of Screening of Goats in Diagnosing of Ketosis
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11:45 AM – 12:45 PM
(825.18) Evaluation of intraperitoneal administration of glucose solution using in the treatment of ketosis in dairy cows
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11:45 AM – 12:45 PM
(826.10) Role of GBP5 in NLRP3 inflammasome mediated intestinal inflammation in Crohn’s disease
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11:45 AM – 12:45 PM
(826.11) Monocytes transition to monocyte-macrophages within the inflamed vasculature via CCR2 on monocytes and endothelial TNFR2
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11:45 AM – 12:45 PM
(826.12) Selection of culture media for chicken PGC long-term cultivation
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11:45 AM – 12:45 PM
(826.13) Pro-Inflammatory Profiling Of RAGE Targeted Mice Following Short-Term Tobacco Exposure
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11:45 AM – 12:45 PM
(826.14) Sex differences in behavior and immune response revealed by a NSAID nanotherapeutic treatment during peripheral neuroinflammation
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11:45 AM – 12:45 PM
(826.15) Misfolding Propensity of SAA1 Fragments: Special Focus on the Signal Peptide Region
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11:45 AM – 12:45 PM
(826.16) Sex-related differences in how hyperactive platelets exacerbate the cytokine storm in the peritoneal cavity during intra-abdominal sepsis
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11:45 AM – 12:45 PM
(827.10) The receptor for advanced glycation endproducts promotes allergen driven neutrophil dominant airway inflammation via NLRP3 inflammasome activation
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12:30 PM – 1:45 PM
(785.1) Crotalus atrox Induced Cellular Injury Triggers an Oxidative Stress Gene Response in HEK-293T Cells
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12:30 PM – 1:45 PM
(785.2) The Effects of Site Specific Histone Modifications on Nucleosomal DNA Accessibility
Favorite
12:30 PM – 1:45 PM
(785.3) H3K9me3 binding analysis of the isolated PHD and TTD domains of UHRF2
Favorite
12:30 PM – 1:45 PM
(785.4) Differential Roles of SWI/SNF Complexes in Metal Regulation
Favorite
12:30 PM – 1:45 PM
(785.5) Transcriptional regulation via strand displacement DNA repair in G-quadruplexes
Favorite
12:30 PM – 1:45 PM
(785.6) Centromere Innovations with a Mouse Species
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12:30 PM – 1:45 PM
(785.7) UL25 Deletion in hCMV and Impacts on Viral Replication Cycles
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12:30 PM – 1:45 PM
(785.8) In Vivo Crosslinking and Mass Spectral Analysis of the Yeast Nucleosomal Protein Interactome
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12:30 PM – 1:45 PM
(785.9) Role of Histone Chaperone APLF in Mammalian Embryo Development
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12:30 PM – 1:45 PM
(786.1) Impaired Transcription Elongation by RNA Polymerase I Results in Defective Ribosomal RNA Processing
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12:30 PM – 1:45 PM
(786.2) Comparative Study of Quantitative TSS Maps among Yeast Strains Demonstrates Key Genetic Sites Required for TSS Selection
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12:30 PM – 1:45 PM
(786.3) HMGN2 regulates transcription factor activity through chromatin modifications and protein interactions, developmentally modulated by microRNA-23
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12:30 PM – 1:45 PM
(786.4) Structural characterization of the cone-rod homeobox protein binding to DNA
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12:30 PM – 1:45 PM
(786.5) Mediator Subunit MED1 Differentially Modulates Mutant Thyroid Hormone Receptor Intracellular Localization and Intranuclear Mobility
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12:30 PM – 1:45 PM
(786.6) Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis
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12:30 PM – 1:45 PM
(786.7) The Codependent Expression of the Essential Mammalian RNA Polymerase I PAF49/PAF53 Heterodimer
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12:30 PM – 1:45 PM
(786.8) Protein-DNA Interactomes of NKX2-5 and TBX5 Mutants Identified in Congenital Heart Defects
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12:30 PM – 1:45 PM
(786.9) A Mass Action Model for Heat Shock Induced Enhancer Transcription
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12:30 PM – 1:45 PM
(787.1) Detecting RNA dynamics in live mammalian cells with fluorescence lifetime-based sensors
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12:30 PM – 1:45 PM
(787.2) Effect of miRNA: MRE Complementarity for SBP-1 Gene Silencing in a Caenorhabditis Elegans Apoptosis Model
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12:30 PM – 1:45 PM
(787.3) Imaging mRNAs with corrected RNA stability
Favorite
12:30 PM – 1:45 PM
(787.4) Divalent cation driven liquid-liquid phase separation of disordered acidic proteins
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12:30 PM – 1:45 PM
(787.5) Gene Therapy for Brain Tumors: Identification of New Therapeutic Targets Based on RNA Structure
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12:30 PM – 1:45 PM
(787.6) Investigating the Role of Base-Triples in the HTLV-1 pro-pol Frameshift Site Pseudoknot
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12:30 PM – 1:45 PM
(787.7) Determining How Stem-loop Structure Thermodynamic Stability Influences Frameshift Efficiency at the HTLV-1 gag-pro Frameshift Site
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12:30 PM – 1:45 PM
(787.8) The small RNA universe of Capitella teleta
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12:30 PM – 1:45 PM
(788.1) MicroRNA Profiling in West Nile Virus Carrying Mosquito, Culex tarsalis
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12:30 PM – 1:45 PM
(788.2) Coring vs scrolls: Inclusion of the muscularis layer on tissue scrolls of the urinary bladder leads to inaccurate miRNA expression
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12:30 PM – 1:45 PM
(788.3) Discovery of novel human long-noncoding RNAs (lncRNAs) associated with inflammation
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12:30 PM – 1:45 PM
(788.4) Long noncoding RNAs in regulation of inflammation, immune response, and glucose metabolism
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12:30 PM – 1:45 PM
(788.5) Identification of Small Regulatory RNA Transcripts in Extracellular Vesicles from Lactic Acid Bacteria
Favorite
12:30 PM – 1:45 PM
(789.1) An Evaluation of the Stability of Splicing Protein Dib1 Through Circular Dichroism Spectroscopy
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12:30 PM – 1:45 PM
(789.2) Strategies for Identifying Important Residues in the tRNA Modification Protein Trm732
Favorite
12:30 PM – 1:45 PM
(789.3) Study of Trm7 Interactions With Binding Partners Trm732 and Trm734 for 2’-O-Methylation of the tRNA Anticodon Loop in Yeast
Favorite
12:30 PM – 1:45 PM
(789.4) Mapping Spatio-temporal ADAR Editing Landscapes in Neurodevelopment
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12:30 PM – 1:45 PM
(789.5) The Effects of Tail Truncations of Pre-Messenger RNA Splicing Protein Dib1
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12:30 PM – 1:45 PM
(789.6) Retinitis Pigmentosa Alleles, in PRPF31 and PRPF6, Effects on Pre-Messenger RNA Splicing
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12:30 PM – 1:45 PM
(789.7) RNA Therapeutics for Brain Tumors: Targeting Pre-mRNA Splicing Motifs to Generate Therapeutic Gene Isoforms
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12:30 PM – 1:45 PM
(789.8) Uncovering Pre-messenger RNA Splicing Mechanisms in Retinitis Pigmentosa
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12:30 PM – 1:45 PM
(789.9) Tissue and Sex-Specific Changes in RNA Editing During Induced Acute Inflammation
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12:30 PM – 1:45 PM
(790.1) SDS-induced amyloid fibrillation of acidic fibroblast growth factor
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12:30 PM – 1:45 PM
(790.2) Identification of Signaling Pathways and Phase Separating Domains that Drive Cajal Body Formation
Favorite
12:30 PM – 1:45 PM
(790.3) Optimizing the cODC degron for Protein Control in Nematode Worms
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12:30 PM – 1:45 PM
(790.4) Using De Novo Designed Protein Switches in C. elegans
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12:30 PM – 1:45 PM
(790.5) TMPRSS11a as a new target in aging
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12:30 PM – 1:45 PM
(790.6) Zebrafish as a Model for Evaluating Coilin-Mediated microRNA Biogenesis
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12:30 PM – 1:45 PM
(790.7) Coilin Modulates Nuclear Organization by Promoting Protein SUMOylation
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12:30 PM – 1:45 PM
(790.8) Dynamic Interaction Network Involving the Conserved Intrinsically Disordered Regions in Human eIF5
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12:30 PM – 1:45 PM
(790.9) Reading the message: Connections between the epigenetic landscape bromodomain activity
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12:30 PM – 1:45 PM
(791.1) in vitro reconstitution of RhoGEF positioning reveals that centralspindlin transports and retains RhoGEF at the plus-end tips of microtubules
Favorite
12:30 PM – 1:45 PM
(791.2) Interface investigation the protein interaction interface between malate dehydrogenase and citrate synthase
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12:30 PM – 1:45 PM
(791.3) Increased fatty acids in Type 1 Diabetes disrupts C-peptide’s transport and downstream effect
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12:30 PM – 1:45 PM
(791.4) Specificity Determinants of Lysine Deacetylases
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12:30 PM – 1:45 PM
(791.5) Investigations of BRAF Regulation through Auto-Inhibition and HRAS Interaction
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12:30 PM – 1:45 PM
(791.6) Functional Inferences Derived from Defining the Interactome of H3K9me2 Writers and Readers
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12:30 PM – 1:45 PM
(791.7) A Tale of Two Scavenger Receptors: Structure-Function Relationships of Purified SR-B1 and CD36
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12:30 PM – 1:45 PM
(791.8) Blood Storage Solutions Effecting Advanced Glycated End Products (AGEs) N-CEL and N-CML on Red Blood Cell Membranes
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12:30 PM – 1:45 PM
(791.9) Multiple pathways for Fig4 contributions to cellular homeostasis in yeast
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12:30 PM – 1:45 PM
(792.1) High Throughput Screening of Protein Arginine N-Methyltransferases – Filter Binding and Phosphor Screening (FBAPS) assay
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12:30 PM – 1:45 PM
(792.2) Proline reduces half-life of homocysteine thiolactone
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12:30 PM – 1:45 PM
(792.3) Quantitative proteomics profiling of lysine 2-hydroxyisobutyrylation in right atrial appendage from rheumatic heart valve disease patients
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12:30 PM – 1:45 PM
(792.4) SIRT1-mediated Lysine Crotonylation is Involved in the Regulation of CaMKII Activity in Myocardium
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12:30 PM – 1:45 PM
(792.5) Investigating Phosphorylation of the Cardiac Potassium Channel hERG using MALDI-TOF Mass Spectrometry
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12:30 PM – 1:45 PM
(792.6) Characterization of Post-translational Modifications of Mitochondrial RNA Polymerase and Mitochondrial Ribosomal Protein L12
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12:30 PM – 1:45 PM
(792.7) SUMO 2 the rescue: how SUMO2 regulates the mitochondria via Drp1 modification
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12:30 PM – 1:45 PM
(792.8) SUMO Regulation of Bir1 in Mitotic Progression
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12:30 PM – 1:45 PM
(792.9) Skeletal muscle alpha actin (ACTA1) acetylation negatively regulates muscle function in response to obesity
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12:30 PM – 1:45 PM
(793.1) Insights into Site-1 Protease Recognition of a Sigma Regulator Involved in Cell Surface Signaling During Pseudomonas capeferrum Pseudobactin BN7/8 Import
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12:30 PM – 1:45 PM
(793.2) Functional analysis of the nitrogenase protective protein CowN
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12:30 PM – 1:45 PM
(793.3) Viperin Catalyzes the Conversion of Cytidine Triphosphate (CTP) to 3′-deoxy-3′,4′-didehydro-CTP by Radical S-adenosylmethionine
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12:30 PM – 1:45 PM
(793.4) The Effect of Potassium on the Structural Flexibility of β-amylase2
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12:30 PM – 1:45 PM
(793.5) Hydrogen-Deuterium Exchange Identifies the Structural Basis of Phase Separation of the Chromosome Passenger Complex
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12:30 PM – 1:45 PM
(793.6) Cryo-EM Structural Determination of Met18, a Scaffold Protein for Iron-Sulfur Protein Maturation
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12:30 PM – 1:45 PM
(793.7) Non-Competitive Inhibition by a Substrate Mimetic of Human 5-Lipoxygenase
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12:30 PM – 1:45 PM
(793.8) Extent of Internal Hydration influence the Activation of GPCR Rhodopsin
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12:30 PM – 1:45 PM
(793.9) Conformations of p90 Ribosomal S6 Kinase (RSK) Activation
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12:30 PM – 1:45 PM
(794.2) Disruption of ATG9A-dependent basal autophagy causes an accumulation of ubiquitin-rich condensates which act as a platform for inflammatory signaling
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12:30 PM – 1:45 PM
(794.3) ATG9A-mediated turnover of p62 condensates requires ubiquitin and occurs independently of the LC3-lipidation machinery
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12:30 PM – 1:45 PM
(794.4) Proteomics, phylogenetics, and co-expression analyses indicate novel interactions in the plastid CLP chaperone-protease system
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12:30 PM – 1:45 PM
(794.5) The strength of WWOX binding with protein partners correlates with cancer suppression and potentially with inhibition of Alzheimers disease progression
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12:30 PM – 1:45 PM
(794.6) Functional Dynamics of Hsp70/CHIP/E2-Ub Complex in Ubiquitination of Substrate Proteins
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12:30 PM – 1:45 PM
(794.7) Development of a gel filtration protocol that eliminates precipitation during refolding of chemically denatured proteins
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12:30 PM – 1:45 PM
(795.1) Kinetic Characterization of a Crystallized Putative Hydroxybutyrate Dehydrogenase from the Opportunistic Pathogen Burkholderia cenocepacia
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12:30 PM – 1:45 PM
(795.2) Computational Study on the Electrostatic Interactions between Uracil-DNA Glycosylase (UDG) and DNA
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12:30 PM – 1:45 PM
(795.3) Evolution of substrate specificity in a maize anthranilate methyltransferase
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12:30 PM – 1:45 PM
(795.4) Toward Understanding the Role of an Active Site Network in LThDP Stabilization on DXPS
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12:30 PM – 1:45 PM
(795.5) Sleuthing for the Enzymatic Activity of an Essential Trypanosoma brucei Haloacid Dehalogenase
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12:30 PM – 1:45 PM
(795.6) The Influence of Identified Key Residues on Catalytic Activity and Substrate Specificity of Taurocyamine Kinases from Arenicola brasiliensis, An Enzyme in the Phosphagen Kinases Family
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12:30 PM – 1:45 PM
(795.7) Shikimate Kinase; Searching for Potential Novel Anti-Tubercular Agents
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12:30 PM – 1:45 PM
(795.8) Biochemical Characterization of Glucan Phosphatases from Cereal Crops
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12:30 PM – 1:45 PM
(795.9) Biochemical Characterization of Starch Excess4 from Storage Crops
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12:30 PM – 1:45 PM
(796.1) Design and Synthesis of Bi-aryl Methylated Lactam Derivatives to Inhibit the BRD7 Bromodomain Function in Prostate Cancer
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12:30 PM – 1:45 PM
(796.2) Determining Antibiotic and Anti-cancer Potential of Small Compounds
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12:30 PM – 1:45 PM
(796.3) Synthesis of Novel Tubulin Inhibitor Candidates as Potential Anti-Cancer Agents
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12:30 PM – 1:45 PM
(796.4) Acidity and nucleophilic reactivity of persulfides
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12:30 PM – 1:45 PM
(796.5) Development of a Novel ELISA for Sensitive Quantitation of Glycogen and Polyglucosan Bodies
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12:30 PM – 1:45 PM
(796.6) Evaluating Anticancer Activity of Isomeric Analogues of the 3,4-Diarylfuranone, PY-407-C
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12:30 PM – 1:45 PM
(796.7) A Computational Biology Approach to pH Selective Reactions in the Extracellular Fluid of Cancer Cells Based in the Gibbs Free Energy Minimization Approach
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12:30 PM – 1:45 PM
(796.8) Scanning-Free functional Fluorescence Microscopy Imaging Toward Spatial Mapping of Biomolecular Information in Live Cell
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12:30 PM – 1:45 PM
(796.9) Molecular Signalling Cascade Time in Sympathetic Stimulation of Angiotensin Renin Axis and Its Correlation With Ultra Low Frequency (ULF) of Heart Rate Variability (HRV)
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12:30 PM – 1:45 PM
(797.1) Methylene Blue – A Potential Therapeutic Treatment for Sodium Fluoroacetate Poisoning
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12:30 PM – 1:45 PM
(797.2) Development of a Liver-Targeted Drug Delivery Platform for Soluble Epoxide Hydrolase Inhibitors
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12:30 PM – 1:45 PM
(797.3) Blocking the entry of HIV into host cells through co-receptor inhibition
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12:30 PM – 1:45 PM
(797.4) Repurposing and Designing Anti-Giardial Drugs Targeting Lipids and Membranes
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12:30 PM – 1:45 PM
(797.5) A Method for Automated Pharmacophore Model Generation Using Multiple Copy Simultaneous Search
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12:30 PM – 1:45 PM
(797.6) In Silico Investigation of Gastroprotective Compounds from n-Butanol Fraction of Costus igneus on Antiulcer Druggable Targets
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12:30 PM – 1:45 PM
(797.7) Developing a COVID-19 Yeast Oral Vaccine for Low Income Countries
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12:30 PM – 1:45 PM
(797.8) Anti-hypertensive effect of BPM4 on spontaneously hypertensive rats that antagonizes Dopamine βeta hydroxylase
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12:30 PM – 1:45 PM
(798.1) Identification of Potential Cellular Responses Triggered by Stereoisomeric DNA Interstrand Crosslinks Produced by Mitomycins in MCF-7 Cells
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12:30 PM – 1:45 PM
(798.2) Potential Signaling Regulations of Stereisomeric DNA Interstrand Crosslinks Produced by Mitomycins in K562 Cells
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12:30 PM – 1:45 PM
(798.3) Anthraquinone derivatives inhibit telomerase activity by interaction with G quadruplex DNA and acts as a promising anticancerous agent
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12:30 PM – 1:45 PM
(798.4) Effect of Over-the-Counter Tooth Whitening Consumer Products of Release of Collagen and Protein from Teeth
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12:30 PM – 1:45 PM
(798.5) Identification and Stratification of Cultured Microorganisms from Wind Cave
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12:30 PM – 1:45 PM
(798.6) To each their own: Disparate abilities of Nrf2 activators to protect against various electrophilic and oxidative insults
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12:30 PM – 1:45 PM
(798.7) Identification of Genes Essential for Sulfamate and Fluorine Incorporation During Nucleocidin Biosynthesis
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12:30 PM – 1:45 PM
(798.8) Evaluation of the protein cross-link breaking effect of selected medicinal plants used in the management of diabetes mellitus
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12:30 PM – 1:45 PM
(798.9) Non-nutritive sweeteners competitively inhibit P-glycoprotein in liver
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12:30 PM – 1:45 PM
(799.1) Revealing human carboxylesterase 1 (CES1) sequence-dependent activity variations using fluorescent chemical tools
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12:30 PM – 1:45 PM
(799.2) Microprobe-based technology for antigen-specific purification of exosomes for OMICS analysis
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12:30 PM – 1:45 PM
(799.3) Novel Chemical Probes targeting the Polyamine Regulatory Circuit
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12:30 PM – 1:45 PM
(799.4) Electrochemical DNA Biosensor to Detect Glycopeptidolipids of Nontuberculous Mycobacteria
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12:30 PM – 1:45 PM
(799.5) An Electrochemical Biosensor for Detection of P.69 Pertactin Associated with B. pertussis
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12:30 PM – 1:45 PM
(799.6) Development of an Electrochemical, DNA-Based Biosensor to the Cancer Biomarker ENOX2
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12:30 PM – 1:45 PM
(800.1) Aromatic C-F Interactions Influence Binding Mode of Inhibitors in HDAC6
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12:30 PM – 1:45 PM
(800.2) Repurposing SARS-CoV-2 Main Protease Inhibitors for HIV-1 Protease Inhibition
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12:30 PM – 1:45 PM
(800.3) Ligand-specific mechanisms of allosteric regulation in FXR
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12:30 PM – 1:45 PM
(800.4) Discovery of the first tight-binding reversible antagonists of Hedgehog protein autoprocessing
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12:30 PM – 1:45 PM
(800.5) Screening of Machine Learning Predicted Inhibitors of Mur-E Ligase
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12:30 PM – 1:45 PM
(800.6) A Novel Zinc Binding Group for HDAC6 Inhibition
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12:30 PM – 1:45 PM
(800.7) Small Molecule Modulation of the Atypical Kinase/ATPase COQ8A
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12:30 PM – 1:45 PM
(800.8) Interactions of TUG-UBL1 and Insulin-Implications for Glucose Uptake
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12:30 PM – 1:45 PM
(801.1) Spatial Whole Transcriptome Profiling of the Tumor Microenvironment in Prostate Carcinomas
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12:30 PM – 1:45 PM
(801.3) A Meta-transcriptomic Analysis of Complicated Diverticulitis Tissue: The Role of Xenobiotics in the Gut
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12:30 PM – 1:45 PM
(801.4) Multi-omics Sample Preparation Workflow for Proteins and DNA Using the Reversible Protein Tag ProMTag
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12:30 PM – 1:45 PM
(801.5) Mass Spectrometry Based Subcellular Coenzyme Analysis
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12:30 PM – 1:45 PM
(801.6) Developing a Prenatal Acute Exposure and Medical Countermeasure Evaluation Model for Organophosphate Compounds in a Genetically Modified Mouse
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12:30 PM – 1:45 PM
(801.7) Cellular Molecular of Osteopontin in the Pathogenesis of Psoriasis
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12:30 PM – 1:45 PM
(801.8) Multi-omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma
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12:30 PM – 1:45 PM
(801.9) Sequencing ACE2 in Bos Taurus: A Comparison of Bovine and Human ACE 2’s interaction with SARS-CoV-2
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12:30 PM – 1:45 PM
(802.1) Testing a multi-factorial model of the role of Rhipicephalus sanguineus in the spread of Rocky Mountain Spotted Fever in the Arizona region
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12:30 PM – 1:45 PM
(802.2) RNA-Seq and Recurrence Risk Testing for Breast Cancer: Implications for Patient Education
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12:30 PM – 1:45 PM
(802.3) Genomic Study of Dopamine Receptor Ligand Binding Sites of the Bivalve Crassostrea virginica
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12:30 PM – 1:45 PM
(802.4) Genomic Study of Histamine Receptor Ligand Binding Sites of the Bivalve Mollusc Crassostrea virginica
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12:30 PM – 1:45 PM
(802.5) Towards the discovery of virulence and survival factors in Fusobacterium using host-mimicking DNA methylation to transcend genetic barriers
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12:30 PM – 1:45 PM
(802.6) Genomic Study of GABA Receptor Ligand Binding Sites of the Bivalve Mollusc Crassostrea virginica
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12:30 PM – 1:45 PM
(802.7) Gene-to-gene damaging variant rate analysis uncovers novel Alzheimer’s disease-associated genes
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12:30 PM – 1:45 PM
(802.8) Genetic polymorphisms and their influence on pancreatic adenocarcinoma progression
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12:30 PM – 1:45 PM
(802.9) Conservation of the trbl Gene Across Drosophila Species: How Does Structure Support Function?
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12:30 PM – 1:45 PM
(803.1) Find out if your protein is O-GlcNAc modified: The O-GlcNAc database
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12:30 PM – 1:45 PM
(803.2) Comprehensive Glycomic Profiling of Breast Cancer Patients
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12:30 PM – 1:45 PM
(804.1) Comparative phylogenetic analysis of the Pyruvyltransferase family
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12:30 PM – 1:45 PM
(804.2) Computational and Mechanistic Study of the Therapeutic Potential of Compound Formononetin in Preventing Mast Cell Activation and IgE Production in Food Anaphylaxis
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12:30 PM – 1:45 PM
(804.3) M-Band Wavelet-Based Imputation of scRNA-seq Matrix and Multi-view Clustering of Cells
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12:30 PM – 1:45 PM
(804.4) MANGO: pipeline for identifying genomic translocations with key biological significance in inflammatory breast cancer
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12:30 PM – 1:45 PM
(804.5) Wavelet Based Machine Learning Approaches Towards Precision Medicine in Diabetes Mellitus
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12:30 PM – 1:45 PM
(804.6) In Vitro Transcription Factor Binding Site Predictions Using Support Vector Machine Classification
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12:30 PM – 1:45 PM
(804.7) Cypin binds to fully polymerized microtubules and tubulin heterodimers via distinct domains
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12:30 PM – 1:45 PM
(804.8) Bioinformatics Analysis of ABCA4 Variants in Terms of Pathogenicity Prediction
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12:30 PM – 1:45 PM
(805.1) Glucose-1-phosphate regulates orphan nuclear receptor NR4A1 and apoptosis
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12:30 PM – 1:45 PM
(805.2) Cephalic Ganglia Transcriptomics of the American Cockroach (Periplaneta americana) Yield Insights into Signaling Infrastructure and Metabolism of the Central Nervous System
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12:30 PM – 1:45 PM
(805.3) Single-Cell RNA-Seq Profiling Identifies L1 Cell Adhesion Molecule (L1cam) as a Mediator in Colonic Tuft Cells - Innate Lymphoid Cell (ILCs) Signaling in the Hnrnp I Knockout Mice
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12:30 PM – 1:45 PM
(805.4) NHE1 as a Target to Block Lung Fibrosis Progression
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12:30 PM – 1:45 PM
(805.5) Polarized Macrophages As Potential Anti-Endometrioid agent
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12:30 PM – 1:45 PM
(805.6) Potential Involvement of NHE1 in COVID-19 Related Pulmonary Damage
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12:30 PM – 1:45 PM
(805.7) Untangling Frizzled functions
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12:30 PM – 1:45 PM
(805.8) Inhibition of Wnt/β-catenin Signaling Pathway on Melanogenesis- Insights from Zebrafish (Danio rerio)
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12:30 PM – 1:45 PM
(805.9) Impact of Redox Modification on MAPK Global Substrate Selection
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12:30 PM – 1:45 PM
(806.1) Alternative GTPase-deficient mutants of Gα12/13 show differences in signaling potency and effector binding
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12:30 PM – 1:45 PM
(806.2) Role of the Gβ5/R7-RGS complex in the regulation of pain transmission in sensory ganglia
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12:30 PM – 1:45 PM
(806.3) New Insights into the Structure-Function Relationships of G Proteins Containing Disease-Associated Mutations
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12:30 PM – 1:45 PM
(806.4) Characterization of molecular basis of anti-platelet effect of daphnetin
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12:30 PM – 1:45 PM
(806.5) Giα and β Proteins Associate in a Complex with Cannabinoid Receptor Interacting Protein 1a (CRIP1a)
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12:30 PM – 1:45 PM
(806.6) Rho5 regulates lysophosphatidic acid induced macropinocytosis in Entamoeba histolytica
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12:30 PM – 1:45 PM
(806.7) A Role for Gβγ in Regulating Golgi fragmentation
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12:30 PM – 1:45 PM
(806.8) Understanding the Role of Gβγ in the Cellular Regulation of Mutationally Activated Gαq/11
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12:30 PM – 1:45 PM
(806.9) Activation of Gαq sequesters specific transcripts into Ago2 particles
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12:30 PM – 1:45 PM
(807.1) The Plastoglobule-localized AtABC1K6 is a Mn2+-dependent Protein Kinase Necessary for Timely Transition to Reproductive Growth
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12:30 PM – 1:45 PM
(807.2) TLK1-MK5 Axis Modulates Actin Filaments and Focal Adhesion Components to Promote PCa Cell Migration and Invasion
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12:30 PM – 1:45 PM
(807.3) Non-canonical Recruitment of PKA Catalytic Subunits to RIα-driven Biomolecular Condensates
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12:30 PM – 1:45 PM
(807.4) Identification of a Pseudosubstrate Stimulatory Motif Uncovers Novel Roles of Cdc14 Phosphatase in Fungal Cell Wall Integrity
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12:30 PM – 1:45 PM
(807.5) A mechanism of ACK1 activation in cancer via C-terminal UBA domain truncation
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12:30 PM – 1:45 PM
(807.6) TLK1 Phosphorylates RAD54 To Promote Homology Driven DSB Repair
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12:30 PM – 1:45 PM
(807.7) Molecular Dynamics Investigation of Oncogenic BRAF Mutations
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12:30 PM – 1:45 PM
(807.8) Investigation of Disease-Causing Point Variants of Vaccinia-Related Kinase 1 (VRK1)
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12:30 PM – 1:45 PM
(807.9) Localization of Cdc14 Isoforms to Ciliary Structures in Tetrahymena thermophila
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12:30 PM – 1:45 PM
(808.1) 5-Fluorouracil and Gemcitabine Alter Nuclear Transport
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12:30 PM – 1:45 PM
(808.2) Potential Synergistic Effects of the Bioflavonoid Quercetin with the Apoptosis-Inducer, TRAIL
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12:30 PM – 1:45 PM
(808.3) A Novel Cell Death Mechanism Involving the Sphingosine-to-Glycerophospholipid Pathway
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12:30 PM – 1:45 PM
(808.4) Ferroptosis Regulation by the NGLY1/NFE2L1 Pathway
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12:30 PM – 1:45 PM
(808.5) Effects of stimulants and HIV Proteins on Pyroptosis and Apoptosis Pathways in Human Brain Microvascular Endothelial (hBMVEC)
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12:30 PM – 1:45 PM
(808.6) Prenylated Stilbenoids as Potential Adjuvants for Paclitaxel in the Treatment of Triple-Negative Breast Cancer
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12:30 PM – 1:45 PM
(808.7) Hypoxia Re-Oxygenation Modelling Using Cancer Cells Expressing Cell Cycle and Cell Death Probes to Understand the Dynamics of Resistance Mechanisms
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12:30 PM – 1:45 PM
(808.8) An endogenous polyunsaturated fatty acid, dihomo-gamma-linoleic acid, induces neurodegeneration in C. elegans via ferroptosis
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12:30 PM – 1:45 PM
(809.1) A Review of MutSα and its Absence in Mismatch Repair Related Ovarian Carcinomas
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12:30 PM – 1:45 PM
(809.2) Molecular Mechanism by which Coumestrol Exerts its Anticancer Activity in Triple-Negative Inflammatory Breast Cancer
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12:30 PM – 1:45 PM
(809.3) NUT Carcinoma: Investigating Drug Synergy and the Production of Drug Resistance
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12:30 PM – 1:45 PM
(809.4) Upregulation of GCLC is Responsible for SFN-induced Tumor Cell Proliferation
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12:30 PM – 1:45 PM
(809.5) cMET inhibition potentiates the tumor-selective damaging effects of NQO1-bioactivatable agents by compromising DNA repair
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12:30 PM – 1:45 PM
(809.6) Small Molecule Anticancer Compound Modulates Cell Cycle DNA Damage Response Pathway and Inhibit Tumorigenesis in Triple Negative Breast Cancer
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12:30 PM – 1:45 PM
(809.7) Investigation of Synergistic Combinations of Chemotherapy Drugs for the Treatment of Oral Cancer
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12:30 PM – 1:45 PM
(809.8) Investigating the chromatin-modulated transcriptional response of cancer cells to drug treatment
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12:30 PM – 1:45 PM
(809.9) Anti-cancer Effects of Coumestrol in Triple-Negative Inflammatory Breast Cancer 3D Models: Opportunities for In Vivo Studies
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12:30 PM – 1:45 PM
(810.1) Normalization of Oxygen-Induced Retinopathy in the Mouse Supplementation with Myo/Nog Cells
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12:30 PM – 1:45 PM
(810.2) CRY-BAR: A versatile light-gated tool for the remodeling of membrane architectures
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12:30 PM – 1:45 PM
(810.3) A Novel Role for Glucocerebrosidase 1 (GBA1) in Parkinson’s Disease
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12:30 PM – 1:45 PM
(810.4) Elucidating the Role of the Electron Transport Chain in Retinal Progenitor Cells and Neuro- regeneration
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12:30 PM – 1:45 PM
(810.5) Regulatory Modulations and Dendritic Arborization in the Mouse Hippocampus Following Gulf War Toxicant Exposure
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12:30 PM – 1:45 PM
(810.6) Sex-specific cholinergic regulation of dopamine release mechanisms through nicotinic receptors in the nucleus accumbens
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12:30 PM – 1:45 PM
(810.7) The Effects of Mild Traumatic Brain Injury (mTBI) on Serotonergic Gene Expression
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12:30 PM – 1:45 PM
(810.8) Does estrogen show neuroprotective effects on hypothalamic cells when induced by beta amyloid?
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12:30 PM – 1:45 PM
(810.9) The primary astrocytic mitochondrial transplantation ameliorates ischemic stroke
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12:30 PM – 1:45 PM
(811.1) Nuclear Entry of DNA Tumor Viruses: Finding the LINC in Nuclear Transport
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12:30 PM – 1:45 PM
(811.2) Trypanosoma cruzi dysregulates expression of piRNA that can regulate IL-6 signaling in human cardiac fibroblasts during the early phase of infection
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12:30 PM – 1:45 PM
(811.3) Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota is Associated with Visceral Hypersensitivity
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12:30 PM – 1:45 PM
(811.4) Comparative Genomics of Bdellovibrionota: Connecting Genotypes with Predation Phenotypes
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12:30 PM – 1:45 PM
(811.5) An Application of Mycobacteriophage Genome Engineering using Bacteriophage Recombineering with Electroporated DNA (BRED) and CRISPR Cas-9 Systems
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12:30 PM – 1:45 PM
(811.6) Bacteriophage Isolation, Characterization and Bioinformatic Genetic Analyses against Actinomycetes Gordonia rubripertincta and Nocardia asteroides
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12:30 PM – 1:45 PM
(811.7) The Analysis and Experimentation of Aspergillus flavus Colonizing Corn in West Tennessee
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12:30 PM – 1:45 PM
(811.8) Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture
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12:30 PM – 1:45 PM
(811.9) Clostridioides difficile surface layer protein triggered inflammasome activation is mediated by membrane lipid raft
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12:30 PM – 1:45 PM
(812.1) How Acinetobacter baumannii Controls Antibiotic Resistance through Phosphorylation of the BfmR Global Regulator
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12:30 PM – 1:45 PM
(812.2) Prevalence of Tuberculosis, Rifampicin Resistant Tuberculosis and Associated Risk Factors in Presumptive Tuberculosis Patients Attending Some Hospitals in Kaduna, Nigeria
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12:30 PM – 1:45 PM
(812.3) Tobramycin Adaptation Alters the Antibiotic Susceptibility of Pseudomonas aeruginosa Quorum Sensing-Null Mutants
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12:30 PM – 1:45 PM
(812.4) Effect of Ciprofloxacin on Planktonic Pseudomonas aeruginosa
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12:30 PM – 1:45 PM
(812.5) Understanding the regulatory effects of a biofilm regulator (BifR) and the implication of its interactions in Burkholderia thailandensis
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12:30 PM – 1:45 PM
(812.6) Outer Membrane Regulation in Acinetobacter: Controlling the Shield against Antibiotics
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12:30 PM – 1:45 PM
(812.7) Providencia alcalifaciens is a Highly Antimicrobial Resistant Bacteria Found in a Suburban Creek
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12:30 PM – 1:45 PM
(812.8) Characterization of Putative Transcriptional Regulator Orf90
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12:30 PM – 1:45 PM
(812.9) Colistin Action Against Planktonic Pseudomonas aeruginosa
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12:30 PM – 1:45 PM
(813.1) Metabolomic characterization of Pseudomonas protegens secretions for identification of biopesticides against Bacterial Panicle Blight of rice
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12:30 PM – 1:45 PM
(813.2) Applying Virtual Screening for Discovery of Novel Inhibitors of Wolbachia Endosymbiont of Brugia malayi Enoyl-Acyl Carrier Protein Reductase (FabI)
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12:30 PM – 1:45 PM
(813.3) Alcohol-based Hand Sanitizer: Comparing Formulations to Aggressively withstand Bacteria
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12:30 PM – 1:45 PM
(813.4) Investigating Potential Therapeutic Activity of Designed Histone Derived Antimicrobial Peptides through Hybridization and Antibiotic Cocktails
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12:30 PM – 1:45 PM
(813.5) Optimization of expression and purification of SUMO-tagged LL-37 peptides
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12:30 PM – 1:45 PM
(813.6) Measuring Cytotoxicity of the Designed Antimicrobial Peptides DesHDAP1 and DesHDAP1-C on Human Embryonic Kidney Cells
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12:30 PM – 1:45 PM
(813.7) Lacritin Bactericidal Peptide N-104 Targeting of Inner Membrane Transporters FeoB and PotH (SpuG) Individually Absent in N-104 Resistant Strains of Human Opportunistic Pathogen, P. aeruginosa PA14
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12:30 PM – 1:45 PM
(813.8) Inhibition of Escherichia coli ATP synthase by dietary pomegranate phenolics
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12:30 PM – 1:45 PM
(814.1) Lysine acetylation during oxidative stress response in the halophilic archaeon Haloferax volcanii
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12:30 PM – 1:45 PM
(814.2) Effect of Sulindac in an in vitro AD Model Under hypoxic conditions.
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12:30 PM – 1:45 PM
(814.3) Role of Stress Granules in the Pathogenesis of Pulmonary Hypertension Kosmas Kosmas 1,2, Fotios Spyropoulos1,2 ,Helen Christou 1,2 1 Department of Pediatric Newborn Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA 2 Harvard Medical School, Boston, MA 02215, USA
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12:30 PM – 1:45 PM
(814.4) Demystifying Cardiac Iron Deficiency in End-stage Heart Failure
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12:30 PM – 1:45 PM
(814.5) Effect of Short-Term and Long-Term Exposure to Sucrose on Protein Expression and Oxidative Modification of Glutathione-S-Transferase Mu 1 (GSTM1) in Liver of Wild Type Mice
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12:30 PM – 1:45 PM
(814.6) Thermal Stress and Antioxidant Activity in Sea Anemones, Exaiptasia pallida
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12:30 PM – 1:45 PM
(814.7) Internal Melanin and Oxidative Stress: An Investigation of Lizard Livers
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12:30 PM – 1:45 PM
(814.8) Antioxidant Effects of Pyrazoles in Ischemia/Reperfusion Injury in Cardiomyocytes
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12:30 PM – 1:45 PM
(815.1) Differential Regulation of Retinoic Acid Signaling in Fanconi Anemia
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12:30 PM – 1:45 PM
(815.2) Increased Fatty Acid Synthesis and Catabolism Supports Metastatic Breast Cancer Cell Migration
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12:30 PM – 1:45 PM
(815.3) High-fat/high-carbohydrate diet increases glycogen accumulation in lung tissue in vivo
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12:30 PM – 1:45 PM
(815.4) Investigating the Conditionally Essential Role of Human METAP1
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12:30 PM – 1:45 PM
(815.5) Can Lactate Dehydrogenase Inhibition be Increased Efficiency of 1,25(OH)2D3 Vitamin in Prostate Cancer Animal Model?
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12:30 PM – 1:45 PM
(815.6) Characterizing Metabolic Changes in Cancer Cells after Treatment with an Extract Created from Walnuts
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12:30 PM – 1:45 PM
(815.7) Mass Spectrometry Imaging Reveals Distinct Differences in Glycogen Accumulation in Lung Tumors from Appalachian Patients
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12:30 PM – 1:45 PM
(815.8) A novel NSC small molecule inhibitor inhibits proliferation of triple-negative breast cancer cells through metabolic reprograming
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12:30 PM – 1:45 PM
(815.9) The Role of Annexin A6 in Triple-negative breast cancer metabolism and disease progression
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12:30 PM – 1:45 PM
(816.1) Real Time Measurement of Hepatic β-oxidation with Deuterium Magnetic Resonance in Murine Models on a High Fat Diet
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12:30 PM – 1:45 PM
(816.2) Brazilian Green Propolis Modulates Cholesterol Homeostasis in a Preclinical Guinea Pig Model
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12:30 PM – 1:45 PM
(816.3) Effect of Transporter Genotype on the Rate of Caffeine Absorption
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12:30 PM – 1:45 PM
(816.4) Characterizing the Drosophila Orthologs of Phosphoglycolate Phosphatase and Pyridoxal Phosphate Phosphatase
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12:30 PM – 1:45 PM
(816.5) Regulation of Energy Metabolism by Dietary pH and Protein Source in Diet-induced Obese Mice and Female Mice
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12:30 PM – 1:45 PM
(816.6) Essential oil metabolites can regulate adrenal androgen production by inhibition of CYP17A1 activities
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12:30 PM – 1:45 PM
(816.7) Effects of Salvia Hispanica on Metabolic Syndrome and Bone in Mouse Osteoblastic Cells – a miRNA analysis
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12:30 PM – 1:45 PM
(816.8) The Horizontally Transferred Arginine Kinase in Myxococcus Xanthus Has Evolved Roles in Multiple Physiological Processes
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12:30 PM – 1:45 PM
(816.9) The Magnitude of Hidden Hunger and Cognitive Deficits of Children Living in Some Selected Orphanages in Kumasi, Ghana During the COVID Pandemic
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12:30 PM – 1:45 PM
(817.1) Generation of an Adeno-Associated Viral Model of Murine Obesity
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12:30 PM – 1:45 PM
(817.3) Elevated Glucose Negatively Regulates Nkx6.1 Protein Level in the Pancreatic Beta Cell
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12:30 PM – 1:45 PM
(817.4) Type 1 Diabetes: A Promising Dialogue between Promiscuous T Cell Receptor and H-2Db Peptide Complex
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12:30 PM – 1:45 PM
(817.5) Hepatic Stearoyl-CoA desaturase deficiency-mediated induction of the insulin-like growth factor-binding protein 1 requires FGF21
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12:30 PM – 1:45 PM
(817.6) The Effects of Metformin on Skeletal Muscle Differentiation and Satellite Cell Function in C2C12 Myocytes and Juvenile Lean and Obese Mice
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12:30 PM – 1:45 PM
(817.7) Association of Pre-Living Kidney Donation Body Mass Index with Post-Donation Estimated Glomerular Filtration Rate Decline
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12:30 PM – 1:45 PM
(817.8) Anti-obesity effect of Premature Citrus Extract in high-fat diet induced obesity mice
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12:30 PM – 1:45 PM
(817.9) Evaluation of the antioxidant activity of the ethyl acetate extract of Potentilla indica on kidneys of streptozotocin-induced diabetic rats
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12:30 PM – 1:45 PM
(818.1) Role of cannabinoids and vitamin E analogues in macrophages foam cells formation
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12:30 PM – 1:45 PM
(818.2) LC-MS based urine metabolomic profiling indicate altered gut microbiome and host lipid metabolites in Parkinson’s disease
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12:30 PM – 1:45 PM
(818.3) Probing the Central Role of Phosphatidylinositol Synthesis in Lipid Metabolism of Eukaryotic Cells
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12:30 PM – 1:45 PM
(818.4) The Yeast Glycogen Synthase Kinase Homolog Rim11 Phosphorylates the Phosphatidic Acid Phosphatase Pah1 to Inhibit its Catalytic Activity
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12:30 PM – 1:45 PM
(818.5) Response of Trypanosoma brucei to Exogenous Fatty Acids in Low Lipid Conditions
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12:30 PM – 1:45 PM
(818.6) Role of Intestinal Stearoyl-CoA Desaturase 1 in Whole-Body Lipid Metabolism and Metabolic Health
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12:30 PM – 1:45 PM
(818.7) Yeast Pah1 PA phosphatase contains a novel domain within its N-terminal intrinsically disordered region
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12:30 PM – 1:45 PM
(818.8) Citric acid cycle metabolites regulate phosphatidate phosphatase activity from the oleaginous yeast Yarrowia lipolytica
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12:30 PM – 1:45 PM
(818.9) Amino Acid Metabolism Controls Fatty Acid Structure in Staphylococcus aureus
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12:30 PM – 1:45 PM
(819.1) Investigating the Role of CRAC in FSH Receptor Function and Structure
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12:30 PM – 1:45 PM
(819.2) CTP:phosphocholine cytidylyltransferase alpha regulates nLD biogenesis in Caco2 cells
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12:30 PM – 1:45 PM
(819.3) Mutations in Caveolin Binding Motif Alter Human Follicle Stimulating Hormone Receptor Signaling
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12:30 PM – 1:45 PM
(819.4) The rate-limiting enzyme in the CDP-choline pathway is regulated by phosphorylation-domain charge density
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12:30 PM – 1:45 PM
(819.5) Altered Lipid Raft Composition Correlates with Oncogenic Potential
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12:30 PM – 1:45 PM
(819.6) Synthetic Assembly of Bacterial Divisome Machinery in Vitro
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12:30 PM – 1:45 PM
(819.7) Lipid Raft Disruption Alters Human Follicle Stimulating Hormone Receptor Signaling
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12:30 PM – 1:45 PM
(819.8) Membrane Phosphoinositides Stabilize GPCR-arrestin Complexes and Provide Temporal Control of Complex Assembly and Dynamics
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12:30 PM – 1:45 PM
(819.9) Structure and Dynamics of Human Perilipin 3 Membrane Association
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12:30 PM – 1:45 PM
(820.1) Selection of GDP-fucose by active site residues in Arabidopsis thaliana SPY
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12:30 PM – 1:45 PM
(820.2) Control of glycosyltransferase activity by nucleotide-binding active site residues in SECRET AGENT
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12:30 PM – 1:45 PM
(820.3) Mechanistic study of nucleotide-sugar binding and catalysis in SECRET AGENT O-GlcNAc Transferase
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12:30 PM – 1:45 PM
(820.4) A Metabolomics-Based Screening System for UDP-Dependent Glycosyltransferases Involved in Wallflower Specialized Metabolism
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12:30 PM – 1:45 PM
(820.5) Exploring new bacterial-fungal interactions: the role of mannan degradation in Streptococci growth
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12:30 PM – 1:45 PM
(820.6) Selective Enrichment of Cell Surface Proteins Using ProMTag to Detect O-glycosylation-Dependent Changes
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12:30 PM – 1:45 PM
(821.1) Serial crystallography and kinetics reveal how the FimH bacterial lectin tweaks between mono- and multivalent binding of high-mannose N-glycans
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12:30 PM – 1:45 PM
(822.1) The bare bones of bifurcation: small flavoproteins as artificial electron bifurcases
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12:30 PM – 1:45 PM
(822.2) Unique structural and dynamic properties of the HNH nuclease in mesophilic and thermophilic Cas9 revealed by NMR
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12:30 PM – 1:45 PM
(822.3) Oxygen Tolerance in the [FeFe] Hydrogenase Cb HydA1
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12:30 PM – 1:45 PM
(822.4) Application of Activity-Based Probe, MV151, in the Mammalian Nervous System Reveals New Insights into Proteasome Changes in Human Alzheimers Disease Brain
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12:30 PM – 1:45 PM
(822.5) Utilization of glucan phosphatase Starch Excess4 to enhance in-vitro starch degradation
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12:30 PM – 1:45 PM
(822.6) PEARL mediated biosynthesis: a novel pathway to aromatic amines
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12:30 PM – 1:45 PM
(822.7) Structure and Mechanism of Mammalian Stearoyl-CoA Desaturase-1 and its Redox Partners
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12:30 PM – 1:45 PM
(822.8) Purification and functional analysis of the ferrous iron transport protein B (FeoB) incorporated into SMA-copolymer nanodiscs
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12:30 PM – 1:45 PM
(822.9) The N-terminal Domain of Twinkle, the Replicative Helicase in Human Mitochondria, Binds DNA and is Essential in Supporting Processive DNA Synthesis by the Mitochondrial DNA Polymerase
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12:30 PM – 1:45 PM
(823.1) ARGs Prevalence Among Hospitalized COVID-19 Patients with Bacterial Infections and Resistome abundance
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12:30 PM – 1:45 PM
(823.2) Role of EnvZ/OmpR Two-component System in Antibiotic Resistance in Salmonella enterica Serovar Enteritidis
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12:30 PM – 1:45 PM
(823.3) Characterization of CarR-CarS Two-Component System Involved in Polymyxin B Resistance of Vibrio vulnificus
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12:30 PM – 1:45 PM
(823.4) Ferric Uptake Regulator (Fur) Regulates Intracellular Iron Homeostasis via reversible binding of a [2Fe-2S] cluster in Escherichia coli
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12:30 PM – 1:45 PM
(823.5) The Role of a Regulatory Protein in the Differing Biofilms of Wild Isolates
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12:30 PM – 1:45 PM
(823.6) Anti-oxidants reverse DNA damage caused by fluconazole in the pathogenic fungus Cryptococcus neoformans
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12:30 PM – 1:45 PM
(823.7) Characterizing the structure and function of phosphatidylinositol-3-phosphate-binding L. pneumophila effectors
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12:30 PM – 1:45 PM
(823.8) Analysis of epidemiology and novel mutation of Helicobacter pylori antibiotic resistance in South Korea
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12:30 PM – 1:45 PM
(823.9) Inhibition of Hsp90 regulates fluconazole resistance in the pathogenic fungus Cryptococcus neoformans
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12:30 PM – 1:45 PM
(824.1) Dissecting the Mechanisms Whereby Tryptophan Metabolites Alter Myocardial Function
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12:30 PM – 1:45 PM
(824.2) Characterizing the transcriptional signature regulated by the AHR ligands TCDD and kynurenine in colon cancer cells
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12:30 PM – 1:45 PM
(824.3) PHB Improves Metabolic Homeostasis in Obese C57BL6 Male Mice Fed a High Fat Diet
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12:30 PM – 1:45 PM
(824.4) Overexpression of human OGG1 improves skeletal muscle endurance in mice
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12:30 PM – 1:45 PM
(824.5) Virus-induced Hepatic Expression of an Oxidized Phospholipid-binding Antibody Fragment Prevents Initiation of Hepatic Steatosis and Progression to Fibrosis
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12:30 PM – 1:45 PM
(824.6) Transcriptome and Mass-Spectrometry-Based Lipidome Reveal a Role of PRMT5 in Membrane Transport and Cholesterol Synthesis in White Adipocytes
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12:30 PM – 1:45 PM
(824.7) Host Regulation of Ebola Virus Egress and Spread: Role of Cytoskeletal Filamin Proteins
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12:30 PM – 1:45 PM
(824.8) Solubilization and purification of phosphatidylserine synthase from Candida albicans
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12:30 PM – 1:45 PM
(824.9) The ERAD system is controlled by ceramides in the endoplasmic reticulum membrane
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12:30 PM – 1:45 PM
(785.10) Investigating the structure of UHRF2 TTD-PHD with H3K9me3
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12:30 PM – 1:45 PM
(785.11) Role of the SWIRM Domain in Regulating the HAT Module of the SAGA Complex
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12:30 PM – 1:45 PM
(785.12) NCLX expression regulation by mild stress conditions
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12:30 PM – 1:45 PM
(785.13) Purification of the human cone-rod homeobox protein
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12:30 PM – 1:45 PM
(785.14) Enhancer regulation by H3K4me1 methyltransferases MLL3/MLL4
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12:30 PM – 1:45 PM
(785.15) Regional and Single Nucleotide Correction of Sequence Bias in Chromatin Accessibility Data
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12:30 PM – 1:45 PM
(785.16) Structure of Saccharomyces cerevisiae Mediator-RNA polymerase II pre-initiation complex for divergent transcription
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12:30 PM – 1:45 PM
(786.10) Simplified, open-source analysis of DNA-binding proteins
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12:30 PM – 1:45 PM
(787.10) Optimization of RNA Display Using GC-Clamp Modifications to Improve Genetic Detection of RNA-Protein Interactions
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12:30 PM – 1:45 PM
(787.11) In Vitro Selection of RNAs That Can Detect Hypoxanthine: A Surprising Technical Issue
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12:30 PM – 1:45 PM
(787.12) Identification of A-B, a Novel Chimeric RNA in Colorectal Cancer
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12:30 PM – 1:45 PM
(787.13) Cellular Localization of Dbp2 and Identification of its Interaction Partners
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12:30 PM – 1:45 PM
(787.14) Micro RNA Expression Profile Analysis in A549 Cancer Cells Treated with Methylsulfonylmethane
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12:30 PM – 1:45 PM
(787.15) 3’ Terminal end-labeling of structured RNA by Klenow DNA polymerase
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12:30 PM – 1:45 PM
(787.16) Interferon Inducible Pseudouridine Modification in Human Transcriptome by Quantitative Nanopore Sequencing
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12:30 PM – 1:45 PM
(790.10) Analysis of the interactions between the HIV-1 Spike and the F7-22 “cooperating” antibody
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12:30 PM – 1:45 PM
(790.11) Exploring ATAD2 bromodomain function in the dynamic epigenetic landscape
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12:30 PM – 1:45 PM
(790.13) A Truncated Mutant – The Most Common Sucrase-Isomaltase Deficiency in the Inuit Population: Cellular and Biochemical Characterization
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12:30 PM – 1:45 PM
(790.14) The Effect of Glycosylation Modulators on the Trafficking and Interaction of Spike Protein S1 Subunit and Angiotensin-Converting Enzyme 2
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12:30 PM – 1:45 PM
(790.15) Design of variants of human fibroblast growth factor 1 with enhanced stability and cell proliferation activity
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12:30 PM – 1:45 PM
(790.16) Biomarkers Indicative of Late Stage Alzheimer’s Disease Found in the Brain and Retina
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12:30 PM – 1:45 PM
(790.17) Monomeric CCTδ Interacts with Dynactin Associated Protein (dynAP)
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12:30 PM – 1:45 PM
(790.18) Crystal Structures of an E1-E2-ubiquitin Thioester Mimetic Reveal Molecular Mechanisms of Transthioesterification
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12:30 PM – 1:45 PM
(790.19) Molecular Mechanism of Vibrio cholerae biofilm adhesion
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12:30 PM – 1:45 PM
(790.20) Reserve-adaptive potential of sperm plasma in stallions of different ages
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12:30 PM – 1:45 PM
(790.21) Applying Crystallography and 19F NMR to investigate dynamics and partner protein interactions in a long chain Flavodoxin
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12:30 PM – 1:45 PM
(790.22) Characterizing BfpU, an Essential Protein in the Type IV Pilus of Enteropathogenic Escherichia coli
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12:30 PM – 1:45 PM
(790.23) Structural basis for environmental sensing in Pseudomonas fluorescens
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12:30 PM – 1:45 PM
(790.24) Heterologous expression of methyl-coenzyme M reductase reveals the importance of organism-specific accessory proteins for proper assembly
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12:30 PM – 1:45 PM
(790.25) Molecular insights into regulation of PI3Kα
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12:30 PM – 1:45 PM
(791.10) Cross-talk between Histone Modifications Modulate Chromatin Reader Activity of the ATAD2B Bromodomain
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12:30 PM – 1:45 PM
(791.11) Identifying Substrates of KDAC6
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12:30 PM – 1:45 PM
(791.12) Elucidation of Bacterial Peptidoglycan Signaling and Recognition in the Human Commensal Candida. albicans through the LRR domain of the peripheral Membrane Protein Cyr1p
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12:30 PM – 1:45 PM
(791.13) A New Method to Self-Associate Proteins Using a Cooperative DNA-binding Protein
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12:30 PM – 1:45 PM
(791.14) The DNA Binding Diversity of the SIX Homeodomain Transcription Factor Family
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12:30 PM – 1:45 PM
(791.15) Structural basis for interactions between RPTPζ/PTPRZ and the perineuronal net component tenascin-R
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12:30 PM – 1:45 PM
(791.16) Cartdridged Food Materials for 3D Printing of Alternative Meat: Regarding Modified Texture of 3D Printed Food according to the Ionic State of Particle Surface exposed on Protein Powder
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12:30 PM – 1:45 PM
(791.17) Understanding the role of RTL8 proteins in Ubiquilin-2 biology
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12:30 PM – 1:45 PM
(791.18) Quantitative Analysis of HPV E2 Binding to DNA Binding Sites and Sequence Variants
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12:30 PM – 1:45 PM
(791.19) Homologues Phospholipases A2 isolated from Naja naja atra snake venom exhibit different activity against intact human erythrocytes
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12:30 PM – 1:45 PM
(792.10) KSHV Manipulation of Antigen Presentation via the Ubiquitin Proteasome System
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12:30 PM – 1:45 PM
(792.11) SIKE’s Phosphorylation Sites Alter Quaternary Structure
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12:30 PM – 1:45 PM
(792.12) Structural Changes Induced in Hsp90 by Nitration lead to a Pathological Gain-of-function
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12:30 PM – 1:45 PM
(792.13) Molecular basis of sequence-dependent differential prenylation inhibition and statin sensitivity of G proteins
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12:30 PM – 1:45 PM
(792.14) Insights into the role of N-linked glycosylation in directing plasma membrane localization of GPCRs expressed in Saccharomyces cerevisiae
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12:30 PM – 1:45 PM
(793.10) Insights into the Binding of the Dengue Virus Nonstructural 5 (NS5) Protein to Stem Loop A (SLA)
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12:30 PM – 1:45 PM
(793.11) Structural studies reveal unique features of nsp16 from SARS-CoV-2, a protein essential for immune system evasion and a possible drug target
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12:30 PM – 1:45 PM
(793.12) Effects of Modulating Multivalent Ligand Binding Accessibility & Affinity on Liquid-Liquid Phase Separation
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12:30 PM – 1:45 PM
(793.13) Functional Extraction and Spectroscopic Investigation of Structural Dynamics in E. coli ATP Synthase
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12:30 PM – 1:45 PM
(793.14) Bioinformatics and 3D Structural Analysis of the Coronavirus Main Protease Active Site Diversity
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12:30 PM – 1:45 PM
(793.15) Structural and regulatory elements of post-translational arginylation
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12:30 PM – 1:45 PM
(793.16) Structural Studies of Copper-Binding Proteins Encoded by the ycn Operon from Bacillus subtilis
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12:30 PM – 1:45 PM
(793.17) Structural investigations of arginyltransferases
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12:30 PM – 1:45 PM
(793.18) Structural Basis for Nanomolar-Affinity Inhibition of Neutrophil Serine Protease Activity by the S. aureus EAP Domain Protein, Eap1
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12:30 PM – 1:45 PM
(795.10) Characterization of the Nickel-inserting Cyclometallase LarC from Moorella thermoacetica and Identification of a CMPylated Reaction Intermediate
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12:30 PM – 1:45 PM
(795.11) Differential expression T4-5’-deiodinase activity in corpulent rats following cold exposure
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12:30 PM – 1:45 PM
(795.12) Mushroom Tyrosinase Assay is used to Teach Enzyme Kinetics and Inhibition Studies in an Undergraduate Biochemistry Course
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12:30 PM – 1:45 PM
(795.13) Kinetic and stability study on the immobilized enzymatic step of one-pot dimerization of 2-[2-(dimethylamino)ethoxy]ethanol
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12:30 PM – 1:45 PM
(796.10) Zinc-Chelating BET Bromodomain Inhibitors Selectively Accumulate and Affect Gene Expression in Pancreatic β-Cells
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12:30 PM – 1:45 PM
(796.11) Allosteric Probes for Modulating Essential Bacterial Chaperone-Cofactor Interactions
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12:30 PM – 1:45 PM
(796.12) Fluorescent detection of RNA using a base excision reporter
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12:30 PM – 1:45 PM
(796.13) High-Performance Computational Molecular Docking for Potential Inhibitors of an Essential Enzyme of Burkholderia pseudomallei
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12:30 PM – 1:45 PM
(796.14) In silico evaluation of inhibitors of Plasmodium falciparum AP2-I transcription factor
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12:30 PM – 1:45 PM
(796.15) Synthesis and Characterization of a nano-bead sunscreen & testing its efficacy
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12:30 PM – 1:45 PM
(796.16) Inhibition of human ERα-positive breast carcinoma cell by baicalein via cell cycle arrest and apoptosis
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12:30 PM – 1:45 PM
(796.17) Comparison of Efficacy and Specificity in Cancer-Targeting Prodrug Conjugates
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12:30 PM – 1:45 PM
(796.18) Targeting Pantothenate Kinase as an Effective Strategy for Antifungal Drug Development
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12:30 PM – 1:45 PM
(798.10) Efficacy of a Patented Menthol-Fortified Phytochemical Formulation in the Alleviation of Joint Pain and Inflammation in Human Subjects: A Clinical Investigation of HerboJoint
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12:30 PM – 1:45 PM
(798.11) Virtual Circular Genome Model for Prebiotically Plausible Nonenzymatic RNA Replication
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12:30 PM – 1:45 PM
(801.10) Investigating the transcriptomic responses in rice roots during interactions with plant growth-promoting bacteria, Burkholderia unamae
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12:30 PM – 1:45 PM
(801.11) Metabolic and Transcriptomic Effects of Mediator Kinase Inhibition on the Interferon Response in Down Syndrome
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12:30 PM – 1:45 PM
(801.12) Search and investigation of potential peptide agents of interaction between human organism and its microbiome
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12:30 PM – 1:45 PM
(801.13) Genome-wide Association Study of Oxidative Phosphorylation in Cocks Semen after Freezing
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12:30 PM – 1:45 PM
(801.14) Computational models elucidate dynamics in the intergenerational inheritance of mtDNA mutations
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12:30 PM – 1:45 PM
(801.15) Genomic characterization of two Salmonella enterica subsp. enterica var. Issatschenko strains possessing selective rodenticidal properties
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12:30 PM – 1:45 PM
(801.16) The diagnostic and prognostic value of COL5A2 high expression and hypomethylation in recurrent low-grade glioma
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12:30 PM – 1:45 PM
(801.17) Contribution of stress granules and spliceosomal components to the formation of chemoresistance in ovarian cancer cells
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12:30 PM – 1:45 PM
(801.18) Analysis of the lake trout heart, blood, liver, and brain proteome using evolutionary proteomics
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12:30 PM – 1:45 PM
(801.19) Label free DIA and DDA nano-LC/MS/MS improved quantitative profiling of redox stress mediated proteomic changes in mouse dendritic cells
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12:30 PM – 1:45 PM
(802.10) Examining Rates of Evolution Within the Drosophila Insulin Signaling Pathway
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12:30 PM – 1:45 PM
(805.10) Carbon Nanoparticles Induce Changes in ER-Stress Gene Expression Levels and Organelle Morphology
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12:30 PM – 1:45 PM
(805.11) The Hsp90 Chaperone Regulates p38 Activation During ER Stress
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12:30 PM – 1:45 PM
(805.12) Effect of Protease Activated Receptor-2 antagonist in the transition from endometrium to endometriosis and ovarian cancer
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12:30 PM – 1:45 PM
(805.13) Protease Activated Receptor-2 (PAR-2) Antagonist potentially ameliorates the SARS-CoV-2 virus-induced Inflammatory Storm
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12:30 PM – 1:45 PM
(805.14) Novel GPR87/SDC-1 Complex Modulates Lacritin Rescue of Homeostasis
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12:30 PM – 1:45 PM
(805.15) Transient modification of macrophages for activation their pro-inflammatory functions
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12:30 PM – 1:45 PM
(805.16) The Role of TLR4 in Pentachlorophenol Stimulation of IL-1β Production in Human Immune Cells
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12:30 PM – 1:45 PM
(805.17) Progranulin as a Context Dependent Signaling Molecule
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12:30 PM – 1:45 PM
(805.18) Bio-Imaging quorum sensing signal molecules in a soil-mimic gel
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12:30 PM – 1:45 PM
(805.19) Cyclin Cs Role in Myoblast Differentiation-Induced Mitochondrial Fragmentation
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12:30 PM – 1:45 PM
(805.20) Role of the Dimerization Domain of Filamin in Dictyostelium discoideum Response to Shear Flow
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12:30 PM – 1:45 PM
(805.21) Role of PTP1B in the Regulation of Cholesterol Homeostasis
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12:30 PM – 1:45 PM
(805.22) Irisin Improves Differentiation through Preserved Mitochondrial Function in Mouse C2C12 Skeletal Muscle Cells
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12:30 PM – 1:45 PM
(805.23) Transmembrane Protein 184A and Syndecan-4 function in the same pathway to promote angiogenesis
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12:30 PM – 1:45 PM
(805.24) Structural Basis of Agonist Capture by Regulatory C1 Domain of PKC
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12:30 PM – 1:45 PM
(805.25) Kinase Responsive to Stress B negatively regulates Rap1 in Dictyostelium discoideum
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12:30 PM – 1:45 PM
(805.26) Investigation of the Adhesion-Modulating Properties of Bovine Serum Albumin (BSA) in Dictyostelium discoideum
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12:30 PM – 1:45 PM
(805.27) MKP-2 Deficiency Improves Insulin Sensitivity and Protects Against Fatty Liver Disease
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12:30 PM – 1:45 PM
(805.28) Regulation of the Age-Dependent Activity of the FOXO Transcription Factor DAF-16 in Adult Caenorhabditis elegans Roundworms
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12:30 PM – 1:45 PM
(805.29) A Cellular & Network Level Investigation of Thalamocortical Neuron Oscillations & the Role of the Transcription Factor, Shox2
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12:30 PM – 1:45 PM
(805.30) Uncovering the mechanistic basis of MAGEA5/A10 driven resistance to chemotherapeutic drugs
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12:30 PM – 1:45 PM
(805.31) Understanding the Structural Basis of Epha1 and Epha2 Homo-Dimerization, Membrane Proximal Domain Interactions and its Implications for Cancer
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12:30 PM – 1:45 PM
(806.10) The Structural Role of the Beta-2 Adrenergic Receptor Function for the Pharmacological Treatment of Cardiopulmonary Diseases
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12:30 PM – 1:45 PM
(807.10) Assembly and Disassembly of PKA is Allosterically Controlled by Nucleotides and Metal Ions
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12:30 PM – 1:45 PM
(807.11) Novel PKC signaling in Alzheimer’s Disease
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12:30 PM – 1:45 PM
(807.12) Human Cdc14 Phosphatase Stimulation by an Intramolecular Pseudosubstrate Motif
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12:30 PM – 1:45 PM
(807.13) PP1cβ dephosphorylates cardiac myosin by MYPT-dependent and independent mechanisms
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12:30 PM – 1:45 PM
(807.14) Untangling the Web of Protein Kinase C Mediated Regulation of Naïve Vs Primed State of Pluripotency
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12:30 PM – 1:45 PM
(808.10) Myo/Nog Cells Migrate to Areas of Cell Death and are Phagocytic in a Murine Model of Retinitis Pigmentosa
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12:30 PM – 1:45 PM
(808.11) Fractionated Lichen Parmelia vagans Extract Exhibits Two distinct Antiproliferative Activities Against Human Cancer Cells
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12:30 PM – 1:45 PM
(808.12) The Role of Monounsaturated Fatty Acids in Ferroptosis
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12:30 PM – 1:45 PM
(809.10) B-Raf: How One Mutation Leads to Melanoma
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12:30 PM – 1:45 PM
(809.11) Anticancer and chemosensitization effects of Wee-1 kinase inhibitor Adavosertib (MK-1775; AZD-1775) in breast cancer cell lines
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12:30 PM – 1:45 PM
(809.12) Pyridoxine and cobalamin supplementation effect regarding cell death in a human glioblastoma cell line
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12:30 PM – 1:45 PM
(809.13) Differential Response of MED12 Downregulated Breast Cancer to Targeted Therapy
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12:30 PM – 1:45 PM
(809.14) Profiling Oncogenic Ras Mutant Drugs with Homogeneous Bioluminescent Immunoassays
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12:30 PM – 1:45 PM
(809.15) A novel cell-based Screening System Identifies Adefovir-dipivoxil as Suppressor of RET expression in medullary thyroid carcinoma
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12:30 PM – 1:45 PM
(809.16) The role of NMDA receptors subunits in the progression of inflammatory breast cancer (IBC).
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12:30 PM – 1:45 PM
(809.17) Natural Compounds as a Promising Therapeutic Agent for SPOP Downregulated Breast Cancer
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12:30 PM – 1:45 PM
(810.10) Manipulation of Igf-1 Expression in the Placenta and Impact on the Fetal Brain
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12:30 PM – 1:45 PM
(811.10) A Ternary Antimicrobial System Assaying Bacteriophage Against Human Pathogens using C. elegans Nematodes
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12:30 PM – 1:45 PM
(812.10) Treatment of Multidrug-Resistant Bacterial Infections Using Quantum Dots
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12:30 PM – 1:45 PM
(812.11) Genesis of Antibiotic Resistance (AR) LXXVI: Turbulence Modeling of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701(ERP-EGDT): Mechanism(s) Time-dependent Fluid Volume Overload Elicit Adverse Pressure Gradient (APG) in metarteriole
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12:30 PM – 1:45 PM
(812.12) Genesis of Antibiotic Resistance (AR) LXXVIII: Turbulence Modeling of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701(ERP-EGDT): Correlation of time (& fluid bolus) dependent pressure drop in boundary layer separation with adverse pressure gradient (APG) in tandem with exacerbated in-hospital mortality (ihm)
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12:30 PM – 1:45 PM
(812.13) Genesis of Antibiotic Resistance (AR) LXXIX: Turbulence Modeling of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701: Linear Correlation of CPPopt, GCS 3-8 and in hospital mortality (ihm)
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12:30 PM – 1:45 PM
(812.14) Genesis of Antibiotic Resistance (AR) LXXX: Turbulence Modeling(TM) of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701: Temporal Correlation of Fluid Bolus, CPPopt(PRx), “Zone of Obstruction”, Comatose (GCS 3), and In-Hospital Mortality (ihm)
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12:30 PM – 1:45 PM
(812.15) Genesis of Antibiotic Resistance (AR) LXXXII: Turbulence Modeling(TM) of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701: The “Von Kármán Vortex Street” (Vasospasm probability index(VPI)) Fillip Zone of Obstruction Consequent Comatose to ihm
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12:30 PM – 1:45 PM
(812.16) Genesis of Antibiotic Resistance (AR) LXXVII: Turbulence Modeling of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701: Fluid Volume Dependent Velocity Profile Spur Adverse Pressure Gradient(APG) in BLS.
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12:30 PM – 1:45 PM
(812.17) Genesis of Antibiotic Resistance (AR) LXXXIII: Turbulence Modeling(TM) of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701: Mechanism(S) of Von Kármán Vortex Street Induced Aberrant Velocity Pattern (Dean Number) Spur In Hospital Mortality (ihm)
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12:30 PM – 1:45 PM
(812.18) Genesis of Antibiotic Resistance (AR) LXXXIV: Turbulence Modeling(TM) of Hemodynamics in Simplified Severe Sepsis Protocol-2 (SSSP-2)-NCT01663701: ISP Afloat Transient APG Thrust VKVS to Hypoxia Rouse Erythropoiesis penultimate to GCS 3, and IHM
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12:30 PM – 1:45 PM
(815.10) A selenium-iron axis dictates cancer cell sensitivity to pharmacologic ascorbate
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12:30 PM – 1:45 PM
(815.11) Effects of cinnamon extract on sirtuin activity: potential for metabolic regulation blood glucose control
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12:30 PM – 1:45 PM
(816.10) Dietary Cholesterol-Induced Gut Microbes Drive Nonalcoholic Fatty Liver Disease Pathogenesis in a Murine Model
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12:30 PM – 1:45 PM
(817.10) Evaluation of the antioxidant effects of green synthesis silver nanoparticles on brain from rats with experimental diabetes
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12:30 PM – 1:45 PM
(817.11) An organism-wide atlas of tissue crosstalk in physical activity
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12:30 PM – 1:45 PM
(817.12) The Bile Acid Receptor Tgr5 and High Fat, High Sugar-Induced Liver Injury
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12:30 PM – 1:45 PM
(817.13) Antioxidant and anti-inflammatory effects of Eryngium carline inflorescences on rat liver diabetic rats
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12:30 PM – 1:45 PM
(818.10) Inhibition of Cardiac Glucose Transport Corrects Diabetic Cardiomyopathy Even Without Alleviation of Hyperglycemia
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12:30 PM – 1:45 PM
(818.11) Loss of ATAD3A contributes to NAFLD through the accumulation of lipids and damaged mitochondria
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12:30 PM – 1:45 PM
(822.10) Mechanistic insight into the initiation step of Methionine-Tyrosine-Tryptophan (MYW) adduct in Mycobacterium tuberculosis KatG
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12:30 PM – 1:45 PM
(822.11) Tunnel Shape of Aldehyde Deformylating Oxygenase Determines Length of Alkane Products
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12:30 PM – 1:45 PM
(822.12) Resonance Raman of the nitrite reductase action of heme-copper oxidoreductases
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12:30 PM – 1:45 PM
(824.10) PIP2 and cholesterol interplay in inflammation and atherosclerosis
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12:30 PM – 1:45 PM
(824.11) Extended-Synaptotagmins Modulate Diacylglycerol Dynamics at the Immunological Synapse in Human T Lymphocytes
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12:30 PM – 1:45 PM
(824.12) Elucidating the role of NUDT19 in renal lipid metabolism
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12:30 PM – 1:45 PM
(824.13) Molecular Basis for Membrane Binding and Lipolysis Activation by ABHD5
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12:30 PM – 1:45 PM
(824.14) Structural basis for Rab6 GTPase activation by the Ric1-Rgp1 complex
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12:30 PM – 1:45 PM
(824.15) Multiple Conserved Cysteine Residues Are Required for Delta-12 Fatty Acid Desaturase Function in Arabidopsis thaliana
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12:30 PM – 1:45 PM
(824.16) Generation and characterization of Elovl4b knockout zebrafish as a model for Juvenile-Onset Macular Degeneration
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12:30 PM – 1:45 PM
(824.17) Structural basis for the activation of Arf1 at the Golgi complex by its GEF Gea2
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