PD56: Kidney Cancer: Localized: Surgical Therapy IV
PD56-11: Comparison of Intermediate Outcomes of Single Port and Multiport Robotic Assisted Partial Nephrectomy
Monday, May 16, 2022
11:10 AM – 11:20 AM
Location: Room 255
Janmejay Hingu, Hackensack, NJ, Tanner Corse, Jay Zaifman*, Nutley, NJ, Ruth Sanchez De La Rosa, Bilal Ahmed Khan, Kevin Alter, Fahad Sheckley, Suzannah Sorin, Gregory Lovallo, Hackensack, NJ, Ravi Munver, Mutahar Ahmed, Michael Stifelman, Nutley, NJ
Introduction: This study aims to compare intermediate surgical outcomes in patients following single port (SP) and multiport (MP) robotic assisted partial nephrectomy (RAPN).
Methods: This is a prospective, single-center study involving 267 patients who underwent SP or MP RAPN between 2017 and 2021 with at least 3 months since surgery and two documented follow up visits. Continuous data was analyzed using the Wilcoxon Rank Sum test. Categorical data was analyzed using Chi-Squared and Fisher's Exact Tests where appropriate. To assess intermediate outcomes, we utilized data from patient visits closest to 6 months following surgery with a median 28 (IQR: 16, 30) and 27 weeks (IQR: 17, 29) for SP and MP, respectively. Disease Free Survival was compared using the Logrank-test and the Kaplan Meier estimator model.
Results: 22 patients (8.23%) underwent SP RAPN and 245 (91.76%) underwent MP RAPN (Table 1) with a median follow up of 35 and 47 weeks, respectively. At time of presentation, there was no significant difference in age, sex, race, chronic kidney disease stage, diabetes status, hypertensive status, or nephrometry score between SP and MP except patients who underwent SP were significantly more likely to have a lower body mass index (26.2 vs 28.7 kg/m2, p=0.027).
In terms of intermediate outcomes, there was no significant difference in changes from baseline preoperative creatinine (+0.21 vs +0.09 mg/dL, p=0.160) and eGFR (-29.7 vs -11.8 mL/min/1.73 m², p=0.520) at the time of 6 month follow up. There was no significant difference in disease recurrence (0.0% vs 4.07%, p=1.0) or disease-free survival (p=0.510) between the two approaches (Figure 1).
Conclusions: Single port robotic assisted partial nephrectomy appears to be an effective treatment modality with equivalent intermediate outcomes to the multiport approach. Further studies are needed to validate long term outcomes.