B0219 - Burden of Eosinophilic Esophagitis 2016-2019: NIS-Based Retrospective Analysis

Amna Shaukat, MBBS¹, Uchit Thapa, MBBS¹, Parikshya Giri Rijal, MBBS¹, Harshith Thyagaturu, MD¹, Lintha Shah, MBBS¹, Samir Jha, MD², Navalok Sharma Ghimire, MBBS¹, Anish Paudel, MD³, Hira Hanif, MD⁴, Prakash Poudel Jaishi, MBBS⁵, Suravi Khanal, MBBS⁶, Aashish K. Singh, MBBS⁷, Jasmine Shrestha, MBBS⁸, Asis Shrestha, MD^9
1Bassett Medical Center, Cooperstown, NY; ²Beth Israel Deaconess Medical Center, Boston, MA; ³Reading Hospital Tower Health, West Reading, PA; ⁴Reading Tower Health, West Reading, PA; ⁵Al Kamil Health Center, Al Kamil, Janub ash Sharqiyah, Oman; ⁶Manipal College of Medical Sciences, Pokhara, Gandaki, Nepal; ⁷APPL, Nongpoh, Meghalaya, India; ⁸Mercy Fort Smith, Fort Smith, AR; ⁹Rochester General Hospital, Rochester, NY

Introduction: Eosinophilic esophagitis (EoE) is a chronic and progressive type 2 inflammatory condition causing significant dysphagia and impaired quality of life. In this review, we aim to study the contemporary prevalence of EoE with gender, racial disparities as well as other baseline characteristics over the course of four years.

Methods: We used the NIS database 2016-2019 to identify patients with eosinophilic esophagitis using the appropriate ICD-10 code (K20.0) which was analyzed using STATA 17.0 software. We evaluated the prevalence, baseline characteristics including gender and racial factors, disease distribution in accordance with regions, length of hospital stay, hospital type, healthcare cost, and associated co-morbidities.

Results: A total of 16,733 adult admissions of EoE were identified between 2016-2019 which accounted for 0.01% of total US hospitalizations. EoE displayed a white race predominance of 81.8% with a mean age of presentation being 47.4 years averaged over the study period. A higher prevalence was seen in males compared to females except in 2016. The average length of hospital stay was 4.5 days which remained stable between 2016-2019 corresponding to an average cost of stay of 55,026 USD with females requiring a slightly longer length of stay. Majority of cases presented to urban teaching hospitals in the southern regions of the United States and required large-sized beds. Rural hospitals also demonstrated a modest increase of 2% EoE cases. Among the EoE patients, 37% were found to be hypertensive, 14.7% were obese and 26.5% were smokers.

Discussion: The prevalence of eosinophilic esophagitis has been increasing for the past two decades which is thought to be due to increased disease recognition by physicians, higher endoscopy volume with biopsies, or both. Our study reported a stable prevalence with a 0.01% proportion of total US hospitalizations with the majority of cases reported in urban teaching hospitals. Interestingly, the cost and length of hospital stay remained relatively stable over the course of four years. It was also observed that the disease is more prevalent in white middle-aged males and in the southern region of the United States which is similar to previous studies. In patients with EoE, nearly 37% were hypertensive and 26% were reported as smokers. Another important observation was the prevalence of obesity in 14.7% of the patient population. Further studies are needed to explore the rise in prevalence of the disease as well as associated co-morbidities.



Disclosures:


Amna Shaukat, MBBS¹, Uchit Thapa, MBBS¹, Parikshya Giri Rijal, MBBS¹, Harshith Thyagaturu, MD¹, Lintha Shah, MBBS¹, Samir Jha, MD², Navalok Sharma Ghimire, MBBS¹, Anish Paudel, MD³, Hira Hanif, MD⁴, Prakash Poudel Jaishi, MBBS⁵, Suravi Khanal, MBBS⁶, Aashish K. Singh, MBBS⁷, Jasmine Shrestha, MBBS⁸, Asis Shrestha, MD⁹. B0219 - Burden of Eosinophilic Esophagitis 2016-2019: NIS-Based Retrospective Analysis, ACG 2022 Annual Scientific Meeting Abstracts. Charlotte, NC: American College of Gastroenterology.