427 - Steven-Johnson Syndrome: A Case Report

Steven-Johnson Syndrome (SJS) is an extremely rare mucocutaneous vesiculobullous reaction that affects approximately 2 to 7 individuals per million people per year.  Caused by immune system activation initiated by a response to medication, SJS may be life-threatening.  There is approximately a 90% incidence of oral mucosal lesions associated with cases, resulting in sequelae such as acute respiratory distress.  This case report follows a 13 year old female patient, who was seen at the Geisinger Medical Center emergency department with SJS. Pediatric dentistry was consulted for “inability to speak and odor associated from oral mucosa”, clinical examination revealed erythematous crusted lesions and grayish-white eroded membranes.  This case report details the remaining clinical findings associated with SJS, the differential diagnoses, and the comprehensive dental treatment rendered to the patient.