172 - A Randomized Controlled Trial Comparing Two Triple Oral Conscious Sedation Regimens.

Purpose: The goal of this study was to assess the success rate of these two oral conscious sedation regimens as well as evaluate other factors that could influence the sedation experience such as age, gender, pre-treatment behavior, behavior during administration of sedation drugs and degree of dental treatment.

Methods: A double-blind randomized controlled trial was performed on a group of thirty patients from 4 to 7 years of age to evaluate the success rate of two oral conscious sedation regimens. The participants were randomly assigned to be sedated using either a combination of midazolam, meperidine and hydroxyzine (midazolam triple regimen) or a combination of chloral hydrate, meperidine and hydroxyzine (chloral hrydrate triple regimen). The evaluation of the child’s behavior was assessed every 10 minutes for a period of 40 minutes using a behavior scale.
Results and

Conclusion: The success rate of chloral hydrate was 80% and midazolam 73.3% and there was no statistically significant difference between the two drug regimens. Demographic factors, pre-treatment behavior, behavior during the administration of the medication, and the amount of dental work that needed to be completed did not influence the success of sedations in either regimen groups.