Student The Royal Veterinary College Potters Bar, United Kingdom
Increasing frequencies of multidrug-resistant infections have been noted in human and veterinary ICU patient populations, emphasizing the importance of appropriate and effective treatment protocols for these patients. Critically ill patients possess a vast array of pathophysiologic changes that can complicate antibiotic dosing, such as increases in the volume of distribution and increased drug clearance. Dosing regimens must adhere to pharmacodynamic principles while also taking into consideration the pharmacokinetics for each patient. Previous studies have shown clinical cure superiority and better efficacy with continuous infusions of antimicrobials as they possess a higher likelihood of attaining pharmacodynamic/pharmacokinetic targets.
Veterinarians will learn about the increasing incidence of multi-drug resistant infections in clinical practice and the practices that can contribute to the incidence of these infections
Veterinarians will learn about the pathophysiologic sequelae of critical illness that can effect the ability to adequately treat with antimicrobials
Veterinarians will be presented with the justification of antimicrobial continuous infusions and how this approach can improve the ability to achieve therapeutic levels of antimicrobials in critically ill patients