Susanne Schnell, PhD University of Greifswald Northwestern University
Organizing and Scientific Committee
Teodora Chitiboi, PhD, Siemens Princeton, USA Albert Hsiao, MD-PhD, San Diego, USA Daniel Messroghli, MD, Berlin, Germany Claudia Prieto, PhD, London, GB Julio Sotelo, PhD, Valparaíso, Chile Jadranka Stojanovca, MD, Michigan, USA Daniel Ennis, PhD, Stanford, California, USA
Overview
Advanced CMR of Cardiac Mechanics and Hemodynamics: Towards Comprehensive and Individualized Evaluation of Heart Disease One of the main strengths of CMR is its versatility in evaluation (i.e. “one-stop-shop”). CMR techniques for cardiac hemodynamics and mechanics have made significant advancements over the last 30+ years, resulting in state-of-the-art 4D flow MRI, real-time phase-contrast MRI, DENSE MRI, and tissue phase mapping, to name a few. Historically, the two (flow and mechanics) camps have evolved independently, even holding separate focus group sessions at ISMRM. From cardiac physiology’s perspective, contractile function and blood flow are intimately linked, with one influencing the other in both direct and indirect pathways. Thus, a CMR examination investigating both aspects has the potential to yield a more complete assessment of cardiac pathophysiology than otherwise. One major barrier to integrating cardiac mechanics and flow scans into a CMR protocol is scan time. Another barrier is the complex image analyses that often require a considerable amount of manual labor. With recent advancements in acceleration methods and automated analysis tools such as artificial intelligence, we are well-positioned to acquire blood flow and mechanics of the heart during the same CMR session and to process both simultaneously to achieve precision medicine for individualized treatment of patients.
This workshop will review and discuss major sequence, protocol, analysis, software and application developments for the evaluation of cardiac mechanics and hemodynamics. Possible topics of the sessions (subject to changes) could be:
Clinical perspectives on cardiac mechanics and hemodynamics
Engineering perspectives on cardiac mechanics and hemodynamics
Fundamentals of image acquisition and analysis methods for flow
Fundamentals of image acquisition and analysis methods for cardiac mechanics
Advanced acceleration techniques for flow and cardiac functional imaging that are necessary for clinical translation
Automated image analysis – including artificial intelligence- techniques for flow and cardiac function that are necessary for clinical translation.
Current clinical applications for CMR of flow and cardiac function
Possible additional items in the program include:
Advanced principles of cardiac mechanics and hemodynamics
Rapid imaging of cardiovascular flow and mechanics
Advanced principles of cardiac image analysis
Expectations: what is needed to make 4D flow CMR practical? (debate)
Is strain CMR ready for clinical routine (debate)
Is commercial software ready for clinical routine (debate)
Current clinical needs: are our radiology, cardiology and surgical colleagues getting what they need?
