PHARMACOLOGY

Cancer and Therapy

Molecular Pharmacology

Neuroscience

3015 - Protein Kinases in Tune

Session Chair(s)

• 

  Alexandra Newton

  University of California, San Diego

This symposium, chaired by the 2019 ASPET Axelrod Awardee, Dr. Alexandra C. Newton, will celebrate the exquisite regulation of protein kinases, one of the largest gene families in humans. The >500 members in this family are instruments nature uses to relay information throughout the cell. Every instrument not only has a precise and finely controlled role in the symphony that controls cell function, but is itself finely tuned for perfect pitch. When these instruments are not in tune, the ensuing cacophony is causal in disease. The symposium will cover protein kinases from structure to biology. The canceled 2020 Axelrod Lecture will be incorporated in this symposium.

Presentations:

• 12:00 PM – 12:18 PM EDT

  Protein Kinase C Out of Tune: Deregulation in Disease
  

  Speaker: Alexandra Newton – University of California, San Diego
• 12:18 PM – 12:36 PM EDT

  Mining the Unexplored Kinome for Novel Oncogenic Kinases
  

  Speaker: John Brognard, PhD – National Cancer Institute (NCI), NIH
• 12:36 PM – 12:54 PM EDT

  New PKA Frontiers from the Dark Kinome
  

  Speaker: Susan Taylor – University of California, San Diego
• 12:54 PM – 1:12 PM EDT

  Environmental Sensing by mTORC1
  

  Speaker: Jenna Jewell – University of Texas Southwestern Medical Center
• 1:12 PM – 1:30 PM EDT

  WNK Signaling through Interaction Motifs
  

  Speaker: Melanie Cobb, PhD – University of Texas Southwestern Medical Center (UTSW)