Lincoln Park High School Chicago, Illinois, United States
Joaquin Berry (Lincoln Park High School)| Jaydon Beaver (Lincoln Park High School)
Lispro is a rapid acting insulin that has been used for keeping blood pressure under control . A rapid acting insulin allows for your body to maintain a balance. This form of insulin is used to treat people with Type 1 and 2 diabetes and keeps your glucose levels from getting too high.
Lispro formerly known as Lyspro is made from the chemical nomenclature and it has a faster subcutaneous absorption rate than other insulins such as Humulin R, Novolin R. Lispro has a reaction time of 15 minutes and peak time of 30 to 90 minutes while Humulin R, Novolin R has a reaction time of 30 to 45 minutes and peak time of 2 to 4 hours. The effects of insulin lispro work well due to the reversal of the two beta chain amino acids proline B-29 and Lysine B-29. Meaning it breaks down into a dimer in less time and then proceeds to a monomer and allows for easy absorption. While this does not change the amount of glucose that has been lowered in the body the insulin peak is earlier as well as higher lessening the chances of hypoglycemia. With the new advances in the pharmaceutical industry for the production of lispro there are still more advancements to be made such as more genetic changes to lispro structure. Lispro is being compared to ASP and insulin pumps (CSII) and in a study done by the American Diabetes association there were favorable effects and transmission of Lispro.