Specialized Pro-Resolving Mediators (SPMs) and Their Role in Actively Resolve Inflammation: Physiological Mechanisms and Immune-Nutrition Solutions for the Increasing Challenge of Inflammatory Health Conditions (Sponsored Satellite Program)

Thursday, June 10, 2021

12:00 PM – 1:30 PM EDT

Sponsored By: Azur Global Nutrition

Chair(s)

SS

Saame Shaikh, PhD

Associate Professor
UNC Chapel Hill
Chapel Hill, North Carolina, United States

Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Speaker(s)

Xavier de la Rosa, PhD

Instructor
CETRI
Boston, Massachusetts, United States

Disclosure: Solutex: Consultant/Advisory Board, I am under Sponsor Research Staff agreement between Solutex and HMS/BWH.
HA

Hildur Arnardottir, PhD

Assistant Professor
Karolinska Instutet
Huddinge, Sweden

Disclosure: Disclosure information not submitted.
Julio Boza Puerta, PhD

CEO
Azur Global Nutrition
Winston-Salem, North Carolina, United States

Disclosure: Azur Global Nutrition: Employee

Learning Objectives:

Describe the active role of SPMs in resolving inflammation
Discuss how an impaired resolution can lead to chronic inflammation
Recognize the difference between SPMs and EPA and DHA (omega-3s)

Access to this session’s recordings are available on ASN on Demand as open access.

Inflammation, specifically unresolved or uncontrolled inflammation, is widely recognized as a critical component of 75% of human chronic diseases, including CVD, atherosclerosis, metabolic syndrome, cancer, osteoarticular health or infection, like the one we are witnessing because of SARS-CoV-2.

Recent research has led to a greater understanding of the acute inflammatory response and the essential role of “specialized pro-resolving mediators” (SPMs) in actively resolving inflammation. SPMs are the active metabolites from EPA and DHA biosynthesized endogenously and are involved in the body’s normal physiological pathways of inflammation, restoring the tissue environment to its normal condition after immune activation and positively influencing infection, pain and tissue and organ protection.

During the session we will review the physiological mechanisms that determine the active termination or resolution of the inflammatory response together with the role of SPMs, and we will discuss the latest knowledge on Covid-19 infectious inflammation as well as the recent data published in humans after SPM supplementation.

Presentations:

12:00 PM – 12:03 PM EDT

Introduction - Specialized Pro-Resolving Mediators (SPMs) and Their Role in Actively Resolve Inflammation: Physiological Mechanisms and Immune-Nutrition Solutions for the Increasing Challenge of Inflammatory Health Conditions (Sponsored Satellite Program)
Speaker: Xavier de la Rosa, PhD – CETRI
12:03 PM – 12:25 PM EDT

Resolution of Inflammation: Key Principles and Role of SPMs (Sponsored Satellite Program)
Speaker: Xavier de la Rosa, PhD – CETRI
12:25 PM – 12:47 PM EDT

Infectious Inflammation – Inflammation and Its Resolution in COVID-19 Syndrome (Sponsored Satellite Program)
Speaker: Hildur Arnardottir, PhD – Karolinska Instutet
12:47 PM – 1:09 PM EDT

Results After SPM Supplementation in Human Patients – A New Immune-Nutrition Therapeutic Approach (Sponsored Satellite Program)
Speaker: Julio Boza Puerta, PhD – Azur Global Nutrition
1:09 PM – 1:30 PM EDT

Panel Discussion - Specialized Pro-Resolving Mediators (SPMs) and Their Role in Actively Resolve Inflammation (Sponsored Satellite Program)
Chair: Saame R. Shaikh, PhD – UNC Chapel Hill
Speaker: Xavier de la Rosa, PhD – CETRI
Speaker: Hildur Arnardottir, PhD – Karolinska Instutet
Speaker: Julio Boza Puerta, PhD – Azur Global Nutrition