Director Rehabilitation Sciences Institute Toronto, Ontario
Research Objectives: To understand how health status preceding traumatic brain injury (TBI) affects relative functional gain after inpatient rehabilitation.
Design: Population-based, sex-stratified, retrospective cohort study using health administrative data.
Setting: Inpatient rehabilitation in Ontario, Canada.
Participants: Patients 14 years or older (N=5,802; 63.4% males) admitted to inpatient rehabilitation within one year of a TBI-related acute care discharge between April 1, 2008, and March 31, 2015.
Main Outcome Measures: Relative functional gain (RFG) in percentage. Health status prior to TBI was identified and internally validated using a data mining approach that categorized all International Classification of Diseases, 10th revision, codes for each patient into 43 factors.
Results: The average RFG was 52.8% +/- 27.6% among male patients and 51.6% +/- 27.1% among female patients. Sex-specific Bonferroni adjusted multivariable linear regressions identified 10 factors of pre-injury health status related to neurology, emergency medicine, cardiology, psychiatry, geriatrics, and gastroenterology that were significantly associated with reduced RFG for male patients. Only one pre-injury health status category, geriatrics, was significantly associated with RFG in female patients.
Conclusions: Pre-existing health conditions present up to five years preceding the TBI event were significantly associated with RFG. These findings should be considered when planning and executing interventions to maximize functional gain and to support an interdisciplinary approach.
Author(s) Disclosures: None.
Identify pre-injury health status significantly associated with functional outcome after inpatient rehabilitation among individuals with traumatic brain injury
Describe the use of data mining approaches in rehabilitation research
Identify sex differences and similarities in pre-injury health status associated with functional outcome among individuals with traumatic brain injury