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Monday Poster Session
Category: Colon
Jordan J. Karlitz, MD, FACG
Denver Health Medical Center and University of Colorado School of Medicine
Denver, CO, United States
COL: colonoscopy; CRC: colorectal cancer; CX: complication; FIT: fecal immunochemical test; LYG: life years gained; mt-sDNA: multi-target stool DNA; a Per 1,000 patients b Lifetime costs include colonoscopy costs, screening costs (stool-based screening costs and follow-up / symptom / surveillance colonoscopies, as relevant), cost of complications, cost of program and cost of CRC). | ||||||||
Analysis | Screening strategy | Number of screening testsa | Total number of COLsa | LYGa | Total costsb | Total QALYs | Incidence reduction | Mortality reduction |
100% adherence screening test 100% follow-up colonoscopy | None | 0 | 80 | 0.00 | $3,091 | 15.100 | 0% | 0% |
mt-sDNA | 3,904 | 1,032 | 228.1 | $4,111 | 15.174 | 46.2% | 51.0% | |
Outreach + FIT | 10,594 | 1,107 | 251.1 | $2,991 | 15.182 | 51.9% | 57.0% | |
Outreach alone | 10,594 | 1,107 | 251.1 | $2,440 | 15.182 | 51.9% | 57.0% | |
Real-world adherence screening test 100% follow-up colonoscopy | None | 0 | 80 | 0.00 | $3,093 | 15.100 | 0% | 0% |
mt-sDNA | 3,205 | 894 | 203.5 | $3,837 | 15.166 | 41.5% | 45.8% | |
Outreach + FIT | 2,755 | 425 | 112.5 | $2,872 | 15.136 | 21.1% | 24.6% | |
Outreach alone | 1,660 | 290 | 73.2 | $2,862 | 15.123 | 13.3% | 15.7% | |
Real-world adherence screening test Real-world follow-up colonoscopy | None | 0 | 80 | 0.00 | $3,097 | 15.100 | 0% | 0% |
mt-sDNA | 3,163 | 611 | 132.8 | $4,030 | 15.143 | 27.3% | 30.0% | |
Outreach + FIT | 2,772 | 301 | 76.3 | $3,013 | 15.123 | 13.9% | 16.5% | |
Outreach alone | 1,653 | 215 | 48.4 | $2,951 | 15.115 | 8.8% | 10.2% |