Hackensack University Medical Center Bergen, NJ, United States
Simcha Weissman, DO1, Muhammad Aziz, MD2, Hannha K. Systrom, MD3, Daniel Elias, BA4, Sameh Elias, MD5, Joesph Feuerstein, MD6 1Hackensack University Medical Center, Bergen, NJ; 2University of Toledo Medical Center, Toledo, OH; 3Beth Israel Deaconess Medical Center, Boston, MA; 4NJMS Medical School, Newark, NJ; 5Palisades Medical Center, Hackensack, NJ; 6Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
Introduction: Preventative care plays an important role in maintaining health in patients with inflammatory bowel disease (IBD). We aimed to assess the overall quality, strength, and transparency of conflicts amongst guidelines on preventative care in IBD.
Methods: A systematic literature search was performed in multiple databases to identify all guidelines pertaining to preventative care in IBD in April 2021. All guidelines were reviewed for transparency of conflicts of interest (COI) and funding, recommendation quality and strength, external guideline review, patient voice inclusion, and plan for update—as per as per Institute of Medicine (IOM) standards. In addition, recommendations and their quality were compared between societies.
Results: 15 distinct societies and a total of 89 recommendations were included. Not all guidelines provided recommendations on key aspects of preventative care in IBD—such as vaccinations, cancer prevention, stress reduction, diet/exercise. 67% of guidelines reported on COI, 20% underwent external review, and 27% included patient representation. 6.7%, 21.3%, and 71.9% of recommendations were based on high, moderate, and low-quality evidence, respectively. 27%, 23.6%, and 49.4% of recommendations were strong, weak/conditional, and did not provide a strength, respectively (Figure 1). The proportion of high-quality evidence (p=0.28) and strong recommendations (p=0.41) did not significantly differ across societies.
Discussion: Many guidelines do not provide recommendations on key aspects of preventative care in IBD. As over 70% of recommendations are based on low-quality evidence, further studies on preventative care in IBD are warranted to improve the overall quality of evidence.
Figure: Figure 1. Scientific level of evidence cited for guideline recommendations on preventative care in Inflammatory bowel disease (IBD) per society, n [%].
Simcha Weissman indicated no relevant financial relationships.
Muhammad Aziz indicated no relevant financial relationships.
Hannha Systrom indicated no relevant financial relationships.
Daniel Elias indicated no relevant financial relationships.
Sameh Elias indicated no relevant financial relationships.
Joesph Feuerstein indicated no relevant financial relationships.
Simcha Weissman, DO1, Muhammad Aziz, MD2, Hannha K. Systrom, MD3, Daniel Elias, BA4, Sameh Elias, MD5, Joesph Feuerstein, MD6. P1645 - Health Maintenance and Preventative Care in Inflammatory Bowel Disease: A Systematic Review of the Overall Quality of Societal Recommendations, ACG 2021 Annual Scientific Meeting Abstracts. Las Vegas, Nevada: American College of Gastroenterology.