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Tuesday Poster Session
Category: Colon
Austin R. Thomas, DO, MA
University of Texas MD Anderson Cancer Center
Hoston, TX, United States
Patient A | Patient B | Patient C | |
Age at diagnosis of fistula / abscess | 74 | 62 | 57 |
Gender | Female | Male | Male |
Primary cancer | Squamous cell carcinoma of tongue | Melanoma of upper back | Melanoma of nose |
ICI | Pembrolizumab | Ipilimumab, nivolumab | Ipilimumab, nivolumab |
Symptoms | Diarrhea | Abdominal pain, fever, pneumaturia | Abdominal pain, diarrhea |
Time to symptom onset after ICI | 13 months | 8 months | 1 month |
Diverticulitis complications | Colovaginal fistula | Colovesical fistula | Diverticular abscess |
Pertinent CT findings | Fistulous tract between sigmoid colon and vaginal cuff, containing small air foci and fluid | Acute diverticulitis, diverticulum with channel to bladder, large amount of gas in bladder | Sigmoid colon diverticulitis with contained abscess, distal small bowel and colonic mucosal enhancement |
Colonoscopy | Diverticulosis, congested and erythematous mucosa from rectum to sigmoid, granularity in distal rectum | Diverticulosis | Diverticulosis, 3 diverticuli with erythema |
Treatment of diverticulitis complications | Antibiotics | Antibiotics | Antibiotics, abscess drainage by IR |
Treatment of GI irAEs | Corticosteroids, vedolizumab, ustekinumab | None | Corticosteroids, vedolizumab |
Cancer status at last follow up | Stable | Stable | Stable |
Vital status | Living | Living | Living |