University of South Carolina School of Medicine Columbia, SC, United States
Philip J. Riddle, MD1, Farzin Rashti, MD2, Hubert Fenton, MD3 1University of South Carolina School of Medicine, Columbia, SC; 2Gastro Center of Maryland, Columbia, MD; 3PrismaHealth, Greenville, SC
Introduction: Schwann cell hamartomas are rare, benign lesions that have been identified throughout the gastrointestinal (GI) tract. They are usually found incidentally in the stomach or colon, but rarely in the esophagus. Herein, we present a case of a Schwann cell hamartoma identified in the esophagus.
Case Description/Methods: A 59 year old male with a history of gastroesophageal reflux disease (GERD) and hiatal hernia status post Nissen fundoplication presented to the gastroenterology office due to recurrence of reflux symptoms despite diet modification and pharmacotherapy. The decision was made to proceed with esophagogastroduodenoscopy (EGD) to better assess the patient’s anatomy given his procedural history. An esophageal sessile polyp (Figure 1, panel A) was identified during EGD and biopsied. A sliding hiatal hernia and multiple gastric polyps were also identified and biopsied. The pathology specimen of the esophageal polyp revealed benign spindle cell proliferation with a neuroid pattern within the lamina propria (Figure 1, panels B and C) consistent with a mucosal Schwann cell hamartoma.
Discussion: A limited number of case reports exist describing mucosal Schwann cell hamartomas elsewhere in the GI tract, but this is the first case we are aware of in the literature identifying a lesion in the esophagus.
Figure: Figure 1. Panel A shows the lesion during EGD. Panel B shows a hematoxylin and eosin stain of the lesion demonstrating Schwann cells in the lamina propria. Panel C shows the lesion stained with S100 demonstrating Schwann cells in the lamina propria.
Philip Riddle indicated no relevant financial relationships.
Farzin Rashti indicated no relevant financial relationships.
Hubert Fenton indicated no relevant financial relationships.
Philip J. Riddle, MD1, Farzin Rashti, MD2, Hubert Fenton, MD3. P0350 - Mucosal Schwann Cell Hamartoma: A Rare Finding in the Esophagus, ACG 2021 Annual Scientific Meeting Abstracts. Las Vegas, Nevada: American College of Gastroenterology.