Endodontist Harvard School of Dental Medicine Boston, Massachusetts
Participants should be aware of the following financial/non-financial relationships:
Elisabetta Cotti, D.D.S., M.S.: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Apical periodontitis should be resolved with a correct root canal treatment which takes care of the infection and promotes healing. Nevertheless the 31-36% of persistent AP has be reported. Many clinical and procedural factors have been correlated to the outcome of endodontic therapy. Furthermore systemic health of the patient, and genetic predisposition of the host may also play a role in healing of apical periodontitis. Some chronic systemic conditions affecting the patients, and new categories of medications (like biologic drugs) offer an interesting insight on unknown aspects of the patient response to endodontic treatment. At the same time the research is bringing to our attention how future protocols may enhance healing of AP (following a state of the art root canal treatment ) by complementing endodontic treatment with both systemic and local immuno-modulatory therapies. Most of this research has been already conducted in the periodontal field. Future direction in the overal treatment of AP will be discussed.
Define the state-of-the-art treatment outcome for apical periodontitis.
Describe the importance of genetic predisposition of the patient and host immune-response on the natural history and response to treatment of apical periodontitis.
Discuss the treatment options provided by new immune-modulatory drugs that boost the host response to apical periodontitis.