Clinica Universidad de Navarra
Dr. Marta M Alonso, Phd; Associate Professor in Pediatrics and coDirector of the NeuroOncology Area at the University Clinic of Navarra, and CoDirector of the Laboratory “Advanced Therapies for Pediatric Tumors”, at the Solid Tumor Program (CIMA, Center for Applied Medical Research). (https://cima.unav.edu/investigacion/programas-verticales/tumores-solidos-biomarcadores/terapias-avanzadas-para-tumores-solidos-pediatricos/equipo).
The overreaching goal of our lab is to improve the prognosis of patients with high-risk pediatric brain tumors. To this end, we integrate clinical and lab-based research to develop tumor-targeted oncolytic adenoviruses with the capacity to elicit a therapeutic immune response in those tumors. Our research uses novel and relevant models to accomplish the experimental aims. We have published extensively and has received continuos funding from prestigious institutions such as the European Research Council or the Department of Defense. Of clinical importance, our research has help to leverage a clinical trial phase I with the oncolytic adenovirus DNX2401 for naïve DIPG tumors.