This session will be a review of regulatory requirements in the form of a game. Categories include 2018 Common Rule, vulnerable subjects, informed consent, investigational drugs, and investigational devices. Attendees will be divided into teams. After a team provides the question to the answer given, the host will provide an explanation for the answer. This session experience will help attendees understand the fundamentals, as well as serve as a refresher for people with advanced knowledge. In addition, attendees will build teamwork skills while developing an answer to questions about human subject research. This session will be hosted in Zoom and attendees are encouraged use the video and audio features to actively participate in the dialogue.