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Research Coordinator
Kessler Foundation
West Orange, New Jersey
BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
Emma Kaplan POSITION TITLE
Research Coordinator
eRA COMMONS USER NAME : ekaplan
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION DEGREE
(if applicable) MM/YY FIELD OF STUDY
University of York, United Kingdom B Sc. 5/1989 Biology
Clinical Research Academy of America, Edison, NJ 5/2012 Clinical Research Associate Certification
Clinical Research Academy of America, Edison, NJ 5/2012 Oracle Clinical Certification
Clinical Research Academy of America, Edison, NJ 5/2012 Clinical Data Management Certification
A. Personal Statement
As a Research Coordinator for the Stroke Rehabilitation Research program, I have the necessary training, and experience to lead and manage stroke rehabilitation research studies. I am trained in clinical research methods and good clinical practices which I have used to participate in various federal and industry-sponsored grants awarded to Kessler Foundation. I bring over 30 years of diverse research experience, and more than 6 years of clinical trial-related work, which includes oversight of database design and maintenance, documentation of patient recruitment and enrollment, data completeness, quality control, and in addition, the generation of files for reporting to the Principal Investigator. In addition, I have participated in a FDA audit with no findings. I have human research experience that includes FDA regulated clinical trials in stroke-rehabilitation Research and federal sponsor grants involving arm rehabilitation after stroke.
My current responsibilities at Kessler Foundation are to oversee adherence to Institutional Review Board protocols as well as participant recruitment, screening, and randomization as well as the day to day activities of a multisite study.
B. Positions and Honors
1989 – 2002 Research Scientist III, II, B, & A - Metabolic and Cardiovascular Diseases.
NOVARTIS PHARMACEUTICALS, East Hanover, NJ
2002 – 2005 Research Scientist - Investigative Product Optimization.
AVENTIS PHARMACEUTICALS, Bridgewater, NJ
2005 – 2012 Research Investigator - Drug Safety Animal Research (DSAR)
SANOFI, Bridgewater, NJ
2013-present Research Assistant, Senior Research Assistant, Research Coordinator; Department of Stroke, Kessler Foundation
Honors and Awards
2019 Best Paper Award, International Conference on Virtual Rehabilitation, Tel Aviv, Israel
C. Peer-reviewed Publications
1. Grigore C. Burdea, Namrata Grampurohit, Nam Kim, Kevin Polistico, Ashwin Kadaru, Simcha Pollack, Mooyeon Oh-Park, A.M. Barrett, Emma Kaplan, Jenny Masmela & Phalgun Nori (2019) Feasibility of integrative games and novel therapeutic game controller for telerehabilitation of individuals chronic post-stroke living in the community, Topics in Stroke Rehabilitation, DOI:
2. Burdea G, K Polistico, N Kim, A Kadaru, D Roll, N Grampurohit, AM Barrett, M Oh-Park, J Masmela, E Kaplan, P Nori and S Pollack. Novel Therapeutic Game Controller for Telerehabilitation of Spastic Hands: Two Case Studies. Proc. Int. Conf. Virtual Rehabilitation 2019, Tel-Aviv Israel.
3. Bebernitz GR, Aicher TD, Stanton JL, Gao J, Shetty SS, Knorr DC, Strohschein RJ, Tan J, Brand LJ, Liu C, Wang WH, Vinluan CC, Kaplan EL, Dragland CJ, DelGrande D, Islam A, Lozito RJ, Liu X, Maniara WM, Mann WR. “Anilides of (R)-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.” J Med Chem. 2000 Jun 1;43(11):2248-57
4. Aicher TD, Anderson RC, Gao J, Shetty SS, Coppola GM, Stanton JL, Knorr DC, Sperbeck DM, Brand LJ, Vinluan CC, Kaplan EL, Dragland CJ, Tomaselli HC, Islam A, Lozito RJ, Liu X, Maniara WM, Fillers WS, DelGrande D, Walter RE, Mann WR. “Secondary amides of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.”
J Med Chem. 2000 Jan 27;43(2):236-49
5. Aicher TD, Damon RE, Koletar J, Vinluan CC, Brand LJ, Gao J, Shetty SS, Kaplan EL, Mann WR “Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK)” Bioorg Med Chem Lett. 1999 Aug 2;9(15):2223-8.
6. Aicher TD, Anderson RC, Bebernitz GR, Coppola GM, Jewell CF, Knorr DC, Liu C, Sperbeck DM, Brand LJ, Strohschein RJ, Gao J, Vinluan CC, Shetty SS, Dragland C, Kaplan EL, DelGrande D, Islam A, Liu X, Lozito RJ, Maniara WM, Walter RE, Mann WR. “(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvte dehydrogenase kinase” J Med Chem. 1999 Jul 29;42(15):2741-6
7. Evans JL, Honer CM, Womelsdorf BE, Kaplan EL, Bell PA. “The effects of Wortmannin, a potent inhibitor of phosphatidyl-inositol 3-kinase, on insulin-stimulated glucose transport, glut4 translocation, antilipolysis, and dna synthesis.” Cell Signal. 1995 May;7(4):365-76.
8. Lögdberg L, Kaplan E, Drelich M, Harfeldt E, Gunn H, Ehrlich P, Dottavio D, Lake P, Ostberg L.. “Primate antibodies to components of the human immune system” J Med Primatol. 1994 Jul;23(5):285-97
D. Research Support
Ongoing Research Support
R01HD058301-05 Adamovich, Meriens, Nolan (PI’s) 7/1/2017-6/30/2022
National Institutes of Health/National Center for Medical Rehabilitation Research
“Optimizing hand rehabilitation post-stroke using interactive virtual environments.”
This project examines intensive, progressive upper extremity training using haptic robots integrated with gaming and virtual reality. We compare behavioral, kinematic and neurophysiological outcomes with early inpatient rehabilitation application of hand training, versus training during transition to the community.
Role: research coordinator
No grant number Peii Chen (PI) 2/1/2017-12/31-2020
Wallerstein Foundation for Geriatric Improvement
“A national research network for spatial neglect.”
By launching a national, practice-based research network partnering twelve inpatient rehabilitation facilities, this project will support full implementation of evidence-based processes to identify and treat one of the most disabling neurological conditions in early recovery of stroke and brain injury, spatial neglect. We will scale the care model by training treatment teams and we will partner to track outcomes of interest to patient, organization and government stakeholders. We expect our group effort will strongly support spatial neglect treatment as cost-effective to enhance independence and function.
Role: research coordinator
CBIR16IRG041 A. M. Barrett (PI) 06/01/2016 – 10/31/2019
New Jersey Commission for Brain Injury Research
“Improving medication self-administration and health after brain injury”
Role: senior research assistant
CBIR16IRG041 Peii Chen (PI) 11/1/2019 – 12/31/2020
New Jersey Commission for Brain Injury Research
“Improving medication self-administration and health after brain injury”
Role: research coordinator
Recently completed
[no grant number] Barrett (site PI) 3/15/2013-6/14/2016
SPR Therapeutics, Inc.
“A randomized, double-blinded, placebo controlled multi-site pivotal study of the SMARTPATCH ™ peripheral nerve stimulation (PNS) system for the treatment of chronic post-stroke shoulder pain.”
This study examines efficacy of a nerve stimulation device to reduce chronic post-stroke shoulder pain.
Role: Research Assistant / Study Coordinator
CBIR14PIL013 A.M. Barrett (PI) 5/31/14-5/30/17
New Jersey Commission on Brain Injury Research
“Medication Self Management after TBI “
Pilot grant proposal to identify/ predict neuropsychological medication self-administration (MSA) errors.
Role: Research Assistant
[no grant number] A.M Barrett (site PI) 9/23/2015-2/8/2018
Dart NeuroScience, LLC
“A Phase 2a, Randomized, Double-Blind, Placebo-Controlled 21-Day Treatment Study, Including an fMRI Sub-Study to Evaluate the Effects of HT-3951 on Upper Extremity Motor Function Following Ischemic Stroke”
Role: Senior Research Assistant/ Study Coordinator
2R44AG044639-04 A.M Barrett (site PI) 10/1/2016-2018
National 1Institute on Aging (NIA)
“Arm Motor Rehabilitation, Entertainment, and Cognition System for the Elderly “
Goal: To investigate the effect of robotic device based virtual reality game on motor recovery of upper limb and cognitive function.
Role: Research Coordinator
1R43AG052290-01 PI: A.M Barrett (site PI) 09/30/2015–08/31/2016
National Institute of Health/NIA
“Remote bimanual virtual rehabilitation for elderly with cerebral vascular disease”
The goal of this project is to demonstrate the feasibility of the proposed BrightBrainer G system for use in home tele-rehabilitation of CVD survivors.
Role: Senior Research Assistant/Study Coordinator
Thursday, October 22, 2020
11:00 AM – 12:15 PM EST