I explore novel interventions to improve extremity use in patients with stroke as well as mechanisms of cortical reorganization and inter-joint coordination associated with such changes. Within the past 23 years I have led several NIH funded clinical trials governing this concept. More recently, our lab has been emphasizing clinical measures of neural plasticity for interventions designed to improve posture in older adults or stroke survivors as well as to improve limb function in the latter group through the addition of electrophysiological (including TMS) and imaging studies. Our newest studies involve use of robotics and mixed reality, both of which have telerehabilitation capabilities and are directed toward home-based treatment post-stroke We also study changes in upper extremity movement following stroke using home base robotic and telerehabilitation interfaces that complement our mixed reality studies. While our studies with stroke survivors have addressed primarily efforts to improve motoric function within the upper extremity, we have also done extensive work in monitoring lower extremity muscle activity to determine the extent to which selective feedback can enhance ambulation amongst stroke survivors. In January 2014 I was asked to serve as co-chairman of the Recovery and Rehabilitation Working Group of the newly NINDS funded Stroke Network in which we are one of 25 sites. This honor provides further opportunity to facilitate recruitment and retention strategies for clinical trials. Most recently we have been funded to participate in a multisite NIH trial on use of telerehabilitation to facilitate upper extremity functional return within 90 days after stroke. This study, led by Steven Cramer, MD, is the first rehabilitation and recovery project funded through the Stroke Network. This work is compatible with our experiences in a successful, home-based robotics study recently completed in collaboration with colleagues at the Cleveland Clinic that targeted chronic stroke survivors. The collective experience in undertaking continuous work in stroke rehabilitation for over 35 years and working with stroke specialists who address motor difficulties faced by these patients, positions me to be of assistance to motor control scientists as well as to partake in oversight of stroke based clinical trials.
Saturday, October 24, 2020
8:30 AM – 9:45 AM EST