Resident Physician Allegheny Health Network Pittsburgh, Pennsylvania
Shifa Umar, MD, Aslam Syed, MD, Talal Seoud, MD, Shyam Thakkar, MD; Allegheny Health Network, Pittsburgh, PA
Introduction: Sexual dysfunction (SD) is common among individuals with chronic illnesses and is associated with distress and reduced quality of life. Currently there are no studies examining sexual dysfunction in patients with chronic pancreatitis (CP). The aim of this study is to describe the prevalence and risk of developing SD in patients with CP. Methods: A population-based study was conducted using a cloud-based, HIPAA compliant web platform Explorys to query aggregated de-identified data from 1999-2020. SNOMED clinical terms were utilized to identify male and female patients with chronic pancreatitis who developed sexual dysfunction by using a temporal relationship. Descriptive statistics for demographics and clinical findings were reported for male and female chronic pancreatitis patients who were diagnosed with sexual dysfunction. Standard 2 by 2 tables were used to calculate the odds ratios (OR) for with standard error and 95% confidence intervals (CI), and P < 0.05 was considered statistically significant Results: Explorys identified 67,680 patients with CP. The overall prevalence of SD was 5% in CP and significantly higher vs. the patients without CP (P < 0.0001). Males (OR 2.47) and females (OR 1.6) with CP have a higher risk of SD vs. patients without CP (P< 0.0001) and more common at age < 65 years old. Prevalence and risk of SD in CP patients with substance use and mental health disorders is described in table 1 and 2. Discussion: SD is an important determinant of quality of life and CP increases risk of SD. Substance abuse and psychiatric comorbid are frequently reported in patients with CP and have been shown to be significant associated factors for SD in our data for CP patients (P < 0.0001). Recognition of mental health issues and sexual dysfunction is essential for providers caring for patients with CP. Recommendations from national society guidelines on behavior and sexual health in CP can improve awareness and appropriate referral for select patients.
Disclosures: Shifa Umar indicated no relevant financial relationships. Aslam Syed indicated no relevant financial relationships. Talal Seoud indicated no relevant financial relationships. Shyam Thakkar indicated no relevant financial relationships.