West Virginia University, School of Medicine Morgantown, West Virginia
Ridwaan Albeiruti, MD, Fahad Chaudhary, MD; West Virginia University, School of Medicine, Morgantown, WV
Introduction: As the management of acute pancreatitis continues to improve over the past 2 decades, we sought to evaluate the impact of gender on in-hospital outcomes for patients with pancreatitis using contemporary inpatient data. Methods: The Nationwide Inpatient Sample (2016) was used to identify adult patients who required hospitalization with a primary diagnosis of acute and chronic pancreatitis. Primary outcomes studied included mortality, acute renal failure, acute respiratory failure and septic shock as well as secondary outcomes including length of stay and hospital cost. These were analyzed using univariate and multivariate comparisons. Results: In 2016, the national estimate for inpatient acute and chronic pancreatitis hospitalizations was 519,035. Of these, 247,505 (48%) patients were female. When comparing baseline characteristics such as mean age at time of hospitalization, mean income, and distribution of ethnicity were similar among the male and female groups. Females were less likely to have alcohol as a cause of pancreatitis (13.2% vs 27.8%, p< 0.001). In regards to clinical outcomes, female patients with pancreatitis had a lower mortality (1.8% vs 2.2%, p< 0.001), respiratory failure (6.5% vs 8.0%, p< 0.001), GI Bleeding (3.6% vs 5.2%, p< 0.001) and septic shock (2.6% vs 3.0%, p< 0.001) while need for endoscopy, length of stay and hospitalization cost were similar. Discussion: Female gender generally tends to fare better when studying in-hospital outcomes in patients with acute pancreatitis. More research is needed into the causes of this gender gap, especially in patients with GI bleeding.
Disclosures: Ridwaan Albeiruti indicated no relevant financial relationships. Fahad Chaudhary indicated no relevant financial relationships.