WVC 91st Annual Conference
There are many causes of chronic diarrhea in dogs and cats. Over the last decade a lot of research has been done to define the normal intestinal microbiome and compare it to that in patients with chronic diarrhea. Until recently, a diagnosis of small intestinal dysbiosis rested on an increased serum folate concentration in combination with a decreased serum cobalamin concentration and response to antimicrobial therapy. However, a newly developed dysbiosis index can be helpful in making that diagnosis. Current treatment of small intestinal dysbiosis includes the use of prebiotics, probiotics, synbiotics, antibiotics, or fecal transplantation.