Formulation and Quality – Chemical
A medication that isn't taken cannot benefit the patient. This is particularly important for orally inhaled drug products (OIDPs) which rely heavily on patient coordination, breathing, and regimen compliance. As pharmaceutical scientists, we tend to focus on how device/formulation interactions affect performance, however, increased attention is being paid to insuring proper interaction between the device and the patient. After years of being plagued by poor patient compliance (as low as 70% noncompliant in some), researchers and developers are now applying technological advances to make these drug products more intuitive for patients, while providing medical professionals the data they need to monitor and adjust therapy. Key areas of improvement have come from new mechanisms of aerosolization, synchronization of aerosol production with breathing patterns and development of data-capturing devices. This presentation will provide a state-of-the-art review of these new technologies used in OIDPs.