Bioanalytics – Biomolecular
End-to-End Hot Topic
Cell therapy is an emerging treatment option with great therapeutic potential. With the demonstrated success in the clinic of CAR-T for cancer treatment, this approach to cell therapy has become a rapidly growing modality for oncology treatment. Unlike conventional small molecules or monoclonal antibody based therapies, cells are dynamic products. They can migrate, proliferate, differentiate, and respond to their environment in vivo. Monitoring and characterizing cell products for use in clinical study are challenging tasks. This talk discusses these challenges and considerations in the context of clinical bioanalysis including bioanalytical strategy, assay development and validation.