Formulation and Quality – Chemical
2018 PharmSci 360
This prologue is an overview of the challenges in formulation, for example over 50% of drugs in development are poorly water soluble. The latest approaches to overcome these challenges will be briefly introduced to set the stage for the proceeding symposium. These will be covered in three broad areas of API, material and technology/processes. There are physicochemical properties, including thermodynamic and structural behaviors of API that are relevant to industry applications of amorphous formulation development. Material and excipient selection criteria based on their functionalities for enabling formulations. The technologies that can be used for enabling formulations, with case studies of recent approved products will be discussed. Upon completion, pharmaceutical scientists will get ideas and information to follow up in detail with the symposium talks.